A majority of m6A residues are in the last exons, allowing the potential for 3′ UTR regulation S Ke, EA Alemu, C Mertens, EC Gantman, JJ Fak, A Mele, B Haripal, ... Genes & development 29 (19), 2037-2053, 2015 | 768 | 2015 |
m6A mRNA modifications are deposited in nascent pre-mRNA and are not required for splicing but do specify cytoplasmic turnover S Ke, A Pandya-Jones, Y Saito, JJ Fak, CB Vågbø, S Geula, JH Hanna, ... Genes & development 31 (10), 990-1006, 2017 | 519 | 2017 |
Activated Expression of an Arabidopsis HD-START Protein Confers Drought Tolerance with Improved Root System and Reduced Stomatal Density H Yu, X Chen, YY Hong, Y Wang, P Xu, SD Ke, HY Liu, JK Zhu, DJ Oliver, ... The Plant Cell 20 (4), 1134-1151, 2008 | 408 | 2008 |
Quantitative evaluation of all hexamers as exonic splicing elements S Ke, S Shang, SM Kalachikov, I Morozova, L Yu, JJ Russo, J Ju, ... Genome research 21 (8), 1360-1374, 2011 | 228 | 2011 |
Pre-mRNA processing includes N6 methylation of adenosine residues that are retained in mRNA exons and the fallacy of “RNA epigenetics” RB Darnell, S Ke, JE Darnell Rna 24 (3), 262-267, 2018 | 87 | 2018 |
Positive selection acting on splicing motifs reflects compensatory evolution S Ke, XHF Zhang, LA Chasin Genome Research 18 (4), 533-543, 2008 | 61 | 2008 |
Saturation mutagenesis reveals manifold determinants of exon definition S Ke, V Anquetil, JR Zamalloa, A Maity, A Yang, MA Arias, S Kalachikov, ... Genome research 28 (1), 11-24, 2018 | 60 | 2018 |
Splicing of designer exons reveals unexpected complexity in pre-mRNA splicing XHF Zhang, MA Arias, S Ke, LA Chasin Rna 15 (3), 367-376, 2009 | 60 | 2009 |
Intronic motif pairs cooperate across exons to promote pre-mRNA splicing S Ke, LA Chasin Genome Biology 11, 1-18, 2010 | 33 | 2010 |
Context-dependent splicing regulation: exon definition, co-occurring motif pairs and tissue specificity S Ke, LA Chasin RNA biology 8 (3), 384-388, 2011 | 29 | 2011 |
Deep learning modeling m6A deposition reveals the importance of downstream cis-element sequences Z Luo, J Zhang, J Fei, S Ke Nature communications 13 (1), 2720, 2022 | 19 | 2022 |
Exon-intron boundary inhibits m6A deposition, enabling m6A distribution hallmark, longer mRNA half-life and flexible protein coding Z Luo, Q Ma, S Sun, N Li, H Wang, Z Ying, S Ke Nature Communications 14 (1), 4172, 2023 | 10 | 2023 |
Splicing by cell type MA Arias, S Ke, LA Chasin Nature biotechnology 28 (7), 686-687, 2010 | 6 | 2010 |
Quantitative Total Definition of Biologically Active Sequence Elements and Positions LA Chasin, S Ke US Patent App. 13/776,696, 2013 | 3 | 2013 |
Quantitative Total Definition of Biologically Active Sequence Elements LA Chasin, S Ke US Patent App. 13/818,777, 2013 | 1 | 2013 |
Pre-mRNA splicing inhibits m6A deposition, allowing longer mRNA half-life and flexible protein coding Z Luo, Q Ma, S Sun, N Li, H Wang, Z Ying, S Ke bioRxiv, 2022.12. 26.521933, 2022 | | 2022 |
Saturation mutagenesis of a human exon S Ke, LA Chasin Intergrative RNA Biology Special Interest Group Meeting, 11, 2014 | | 2014 |
Human pseudo exons,~ 92000 LA Chasin, S Ke, A Wang | | 2007 |