Structural Rearrangements Underlying K+-Channel Activation Gating E Perozo, D Marien, Cortes, LG Cuello Science 285 (5424), 73-78, 1999 | 671 | 1999 |
Structural mechanism of C-type inactivation in K+ channels LG Cuello, V Jogini, DM Cortes, E Perozo Nature 466 (7303), 203-208, 2010 | 541 | 2010 |
Molecular determinants of gating at the potassium-channel selectivity filter JF Cordero-Morales, LG Cuello, Y Zhao, V Jogini, DM Cortes, B Roux, ... Nature structural & molecular biology 13 (4), 311-318, 2006 | 490 | 2006 |
Three-dimensional architecture and gating mechanism of a K+ channel studied by EPR spectroscopy E Perozo, DM Cortes, LG Cuello Nature structural biology 5 (6), 459-469, 1998 | 387 | 1998 |
pH-dependent gating in the Streptomyces lividans K+ channel LG Cuello, JG Romero, DM Cortes, E Perozo Biochemistry 37 (10), 3229-3236, 1998 | 315 | 1998 |
Structural basis for the coupling between activation and inactivation gates in K+ channels LG Cuello, V Jogini, DM Cortes, AC Pan, DG Gagnon, O Dalmas, ... Nature 466 (7303), 272-275, 2010 | 312 | 2010 |
Molecular Architecture of Full-Length KcsA Role of Cytoplasmic Domains in Ion Permeation and Activation Gating DM Cortes, LG Cuello, E Perozo The Journal of general physiology 117 (2), 165-180, 2001 | 289 | 2001 |
Molecular architecture of the KvAP voltage-dependent K+ channel in a lipid bilayer LG Cuello, DM Cortes, E Perozo Science 306 (5695), 491-495, 2004 | 272 | 2004 |
Voltage-dependent gating at the KcsA selectivity filter JF Cordero-Morales, LG Cuello, E Perozo Nature structural & molecular biology 13 (4), 319-322, 2006 | 161 | 2006 |
Detection of the opening of the bundle crossing in KcsA with fluorescence lifetime spectroscopy reveals the existence of two gates for ion conduction R Blunck, JF Cordero-Morales, LG Cuello, E Perozo, F Bezanilla The Journal of general physiology 128 (5), 569-581, 2006 | 131 | 2006 |
Structural dynamics of an isolated voltage-sensor domain in a lipid bilayer S Chakrapani, LG Cuello, DM Cortes, E Perozo Structure 16 (3), 398-409, 2008 | 102 | 2008 |
The gating cycle of a K+ channel at atomic resolution LG Cuello, DM Cortes, E Perozo Elife 6, e28032, 2017 | 99 | 2017 |
A designer ligand specific for Kv1. 3 channels from a scorpion neurotoxin-based library Z Takacs, M Toups, A Kollewe, E Johnson, LG Cuello, G Driessens, ... Proceedings of the National Academy of Sciences 106 (52), 22211-22216, 2009 | 89 | 2009 |
Mechanism of activation gating in the full-length KcsA K+ channel S Uysal, LG Cuello, DM Cortes, S Koide, AA Kossiakoff, E Perozo Proceedings of the National Academy of Sciences 108 (29), 11896-11899, 2011 | 88 | 2011 |
Rapid constriction of the selectivity filter underlies C-type inactivation in the KcsA potassium channel J Li, J Ostmeyer, LG Cuello, E Perozo, B Roux Journal of General Physiology 150 (10), 1408-1420, 2018 | 73 | 2018 |
A molecular mechanism for proton-dependent gating in KcsA LG Cuello, DM Cortes, V Jogini, A Sompornpisut, E Perozo FEBS letters 584 (6), 1126-1132, 2010 | 65 | 2010 |
Thermodynamic coupling between activation and inactivation gating in potassium channels revealed by free energy molecular dynamics simulations AC Pan, LG Cuello, E Perozo, B Roux Journal of General Physiology 138 (6), 571-580, 2011 | 59 | 2011 |
Gating of the proton-gated ion channel from Gloeobacter violaceus at pH 4 as revealed by X-ray crystallography G Gonzalez-Gutierrez, LG Cuello, SK Nair, C Grosman Proceedings of the National Academy of Sciences 110 (46), 18716-18721, 2013 | 53 | 2013 |
A lipid site shapes the agonist response of a pentameric ligand-gated ion channel CM Hénault, C Govaerts, R Spurny, M Brams, A Estrada-Mondragon, ... Nature chemical biology 15 (12), 1156-1164, 2019 | 50 | 2019 |
Thioredoxin reverses age-related hypertension by chronically improving vascular redox and restoring eNOS function RHP Hilgers, V Kundumani-Sridharan, J Subramani, LC Chen, LG Cuello, ... Science translational medicine 9 (376), eaaf6094, 2017 | 50 | 2017 |