Design of polymeric carriers for cancer-specific gene targeting: utilization of abnormal protein kinase Cα activation in cancer cells JH Kang, D Asai, JH Kim, T Mori, R Toita, T Tomiyama, Y Asami, J Oishi, ... Journal of the American Chemical Society 130 (45), 14906-14907, 2008 | 97 | 2008 |
Protein kinase C (PKC) isozyme-specific substrates and their design JH Kang, R Toita, CW Kim, Y Katayama Biotechnology advances 30 (6), 1662-1672, 2012 | 95 | 2012 |
Anti-obesity and anti-inflammatory effects of macrophage-targeted interleukin-10-conjugated liposomes in obese mice R Toita, T Kawano, M Murata, JH Kang Biomaterials 110, 81-88, 2016 | 73 | 2016 |
Liver cell-targeted delivery of therapeutic molecules JH Kang, R Toita, M Murata Critical reviews in biotechnology 36 (1), 132-143, 2016 | 62 | 2016 |
Phosphorylation of Rho-associated kinase (Rho-kinase/ROCK/ROK) substrates by protein kinases A and C JH Kang, Y Jiang, R Toita, J Oishi, K Kawamura, A Han, T Mori, T Niidome, ... Biochimie 89 (1), 39-47, 2007 | 62 | 2007 |
A nanocarrier based on a genetically engineered protein cage to deliver doxorubicin to human hepatocellular carcinoma cells R Toita, M Murata, K Abe, S Narahara, JS Piao, JH Kang, M Hashizume Chemical Communications 49 (67), 7442-7444, 2013 | 57 | 2013 |
Immobilization of calcium and phosphate ions improves the osteoconductivity of titanium implants R Toita, K Tsuru, K Ishikawa Materials Science and Engineering: C 68, 291-298, 2016 | 55 | 2016 |
Development of human hepatocellular carcinoma cell-targeted protein cages R Toita, M Murata, S Tabata, K Abe, S Narahara, JS Piao, JH Kang, ... Bioconjugate chemistry 23 (7), 1494-1501, 2012 | 55 | 2012 |
A short peptide is a protein kinase C (PKC) α‐specific substrate JH Kang, D Asai, S Yamada, R Toita, J Oishi, T Mori, T Niidome, ... Proteomics 8 (10), 2006-2011, 2008 | 48 | 2008 |
Surface plasma treatment and phosphorylation enhance the biological performance of poly (ether ether ketone) N Fukuda, A Tsuchiya, R Toita, K Tsuru, Y Mori, K Ishikawa Colloids and Surfaces B: Biointerfaces 173, 36-42, 2019 | 43 | 2019 |
A superhydrophilic titanium implant functionalized by ozone gas modulates bone marrow cell and macrophage responses Sunarso, R Toita, K Tsuru, K Ishikawa Journal of Materials Science: Materials in Medicine 27, 1-9, 2016 | 43 | 2016 |
Plasma protein kinase C (PKC) α as a biomarker for the diagnosis of cancers JH Kang, D Asai, R Toita, H Kitazaki, Y Katayama Carcinogenesis 30 (11), 1927-1931, 2009 | 42 | 2009 |
Modulation of the osteoconductive property and immune response of poly (ether ether ketone) by modification with calcium ions R Toita, Sunarso, AN Rashid, K Tsuru, K Ishikawa Journal of Materials Chemistry B 3 (44), 8738-8746, 2015 | 40 | 2015 |
Effect of micro-roughening of poly (ether ether ketone) on bone marrow derived stem cell and macrophage responses, and osseointegration Sunarso, A Tsuchiya, N Fukuda, R Toita, K Tsuru, K Ishikawa Journal of Biomaterials Science, Polymer Edition 29 (12), 1375-1388, 2018 | 39 | 2018 |
Synergistic effect of surface phosphorylation and micro-roughness on enhanced osseointegration ability of poly (ether ether ketone) in the rabbit tibia N Fukuda, M Kanazawa, K Tsuru, A Tsuchiya, Sunarso, R Toita, Y Mori, ... Scientific reports 8 (1), 16887, 2018 | 37 | 2018 |
Biological evaluation of protein nanocapsules containing doxorubicin R Toita, M Murata, K Abe, S Narahara, JS Piao, JH Kang, K Ohuchida, ... International journal of nanomedicine, 1989-1999, 2013 | 37 | 2013 |
A protein kinase assay based on FRET between quantum dots and fluorescently-labeled peptides S Shiosaki, T Nobori, T Mori, R Toita, Y Nakamura, CW Kim, T Yamamoto, ... Chemical Communications 49 (49), 5592-5594, 2013 | 34 | 2013 |
Liver cell specific targeting by the preS1 domain of hepatitis B virus surface antigen displayed on protein nanocages M Murata, S Narahara, K Umezaki, R Toita, S Tabata, JS Piao, K Abe, ... International journal of nanomedicine, 4353-4362, 2012 | 34 | 2012 |
Gene carrier showing all-or-none response to cancer cell signaling R Toita, JH Kang, T Tomiyama, CW Kim, S Shiosaki, T Niidome, T Mori, ... Journal of the American Chemical Society 134 (37), 15410-15417, 2012 | 33 | 2012 |
Bio and nanotechnological strategies for tumor-targeted gene therapy JH Kang, R Toita, Y Katayama Biotechnology advances 28 (6), 757-763, 2010 | 33 | 2010 |