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Martijn van den Bosch
Martijn van den Bosch
Postdoctoral researcher, Radboud university medical center
在 radboudumc.nl 的电子邮件经过验证 - 首页
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引用次数
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年份
Alarmins S100A8 and S100A9 elicit a catabolic effect in human osteoarthritic chondrocytes that is dependent on Toll‐like receptor 4
RFP Schelbergen, AB Blom, MHJ van den Bosch, A Slöetjes, ...
Arthritis & Rheumatism 64 (5), 1477-1487, 2012
2102012
Osteoarthritis year in review 2020: biology
MHJ van den Bosch
Osteoarthritis and cartilage 29 (2), 143-150, 2021
1662021
Inflammation in osteoarthritis: is it time to dampen the alarm (in) in this debilitating disease?
MHJ Van den Bosch
Clinical & Experimental Immunology 195 (2), 153-166, 2019
1252019
Alarmins S100A8/S100A9 aggravate osteophyte formation in experimental osteoarthritis and predict osteophyte progression in early human symptomatic osteoarthritis
RFP Schelbergen, W de Munter, MHJ Van den Bosch, F Lafeber, ...
Annals of the rheumatic diseases 75 (1), 218-225, 2016
1012016
Identifying effector molecules, cells, and cytokines of innate immunity in OA
MHJ Van den Bosch, P Van Lent, PM Van der Kraan
Osteoarthritis and Cartilage 28 (5), 532-543, 2020
942020
Canonical Wnt signaling skews TGF-β signaling in chondrocytes towards signaling via ALK1 and Smad 1/5/8
MH van den Bosch, AB Blom, PL van Lent, HM van Beuningen, ...
Cellular signalling 26 (5), 951-958, 2014
852014
Prophylactic treatment with S100A9 inhibitor paquinimod reduces pathology in experimental collagenase-induced osteoarthritis
RF Schelbergen, EJ Geven, MHJ Van Den Bosch, H Eriksson, ...
Annals of the rheumatic diseases 74 (12), 2254-2258, 2015
832015
Interleukin-1 is not involved in synovial inflammation and cartilage destruction in collagenase-induced osteoarthritis
SCM Van Dalen, AB Blom, AW Slöetjes, MMA Helsen, J Roth, T Vogl, ...
Osteoarthritis and cartilage 25 (3), 385-396, 2017
762017
Alarmin S100A9 induces proinflammatory and catabolic effects predominantly in the M1 macrophages of human osteoarthritic synovium
MH van den Bosch, AB Blom, RF Schelbergen, MI Koenders, ...
The Journal of rheumatology 43 (10), 1874-1884, 2016
762016
Induction of canonical Wnt signaling by synovial overexpression of selected Wnts leads to protease activity and early osteoarthritis-like cartilage damage
MH van den Bosch, AB Blom, AW Sloetjes, MI Koenders, FA van de Loo, ...
The American journal of pathology 185 (7), 1970-1980, 2015
682015
High LDL levels lead to increased synovial inflammation and accelerated ectopic bone formation during experimental osteoarthritis
W de Munter, MH Van Den Bosch, AW Slöetjes, KJ Croce, T Vogl, J Roth, ...
Osteoarthritis and cartilage 24 (5), 844-855, 2016
662016
WISP1/CCN4 aggravates cartilage degeneration in experimental osteoarthritis
MH Van den Bosch, AB Blom, V Kram, A Maeda, S Sikka, Y Gabet, ...
Osteoarthritis and Cartilage 25 (11), 1900-1911, 2017
452017
Macrophage-derived extracellular vesicles as carriers of alarmins and their potential involvement in bone homeostasis
BCH Pieters, A Cappariello, MHJ Van den Bosch, PLEM Van Lent, A Teti, ...
Frontiers in immunology 10, 1901, 2019
442019
S100A8/A9 increases the mobilization of pro-inflammatory Ly6Chigh monocytes to the synovium during experimental osteoarthritis
NAJ Cremers, MHJ van den Bosch, S van Dalen, I Di Ceglie, G Ascone, ...
Arthritis research & therapy 19, 1-15, 2017
422017
Induction of canonical Wnt signaling by the alarmins S100A8/A9 in murine knee joints: implications for osteoarthritis
MH van den Bosch, AB Blom, RFP Schelbergen, T Vogl, JP Roth, ...
Arthritis & rheumatology 68 (1), 152-163, 2016
372016
Wnts talking with the TGF-β superfamily: WISPers about modulation of osteoarthritis
MH van den Bosch, TA Gleissl, AB Blom, WB van den Berg, PL van Lent, ...
Rheumatology 55 (9), 1536-1547, 2016
322016
S100A8/A9, a potent serum and molecular imaging biomarker for synovial inflammation and joint destruction in seronegative experimental arthritis
EJW Geven, MHJ van den Bosch, I Di Ceglie, G Ascone, ...
Arthritis Research & Therapy 18, 1-12, 2016
282016
Post-traumatic knee osteoarthritis; the role of inflammation and hemarthrosis on disease progression
BJ Evers, MHJ Van Den Bosch, AB Blom, PM van der Kraan, S Koëter, ...
Frontiers in medicine 9, 973870, 2022
262022
Brief report: induction of matrix metalloproteinase expression by synovial Wnt signaling and association with disease progression in early symptomatic osteoarthritis
MH van den Bosch, AB Blom, FA van de Loo, MI Koenders, FP Lafeber, ...
Arthritis & Rheumatology 69 (10), 1978-1983, 2017
262017
Imaging, myeloid precursor immortalization, and genome editing for defining mechanisms of leukocyte recruitment in vivo
S Gran, L Honold, O Fehler, S Zenker, S Eligehausen, MT Kuhlmann, ...
Theranostics 8 (9), 2407, 2018
252018
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