Principles of asymmetric synthesis RE Gawley, J Aubé Elsevier, 2012 | 474 | 2012 |
MAIT cells are imprinted by the microbiota in early life and promote tissue repair MG Constantinides, VM Link, S Tamoutounour, AC Wong, ... Science 366 (6464), eaax6624, 2019 | 421 | 2019 |
The internal quaternary ammonium receptor site of Shaker potassium channels KL Choi, C Mossman, J Aubé, G Yellen Neuron 10 (3), 533-541, 1993 | 332 | 1993 |
Improvement of oral peptide bioavailability: Peptidomimetics and prodrug strategies GM Pauletti, S Gangwar, TJ Siahaan, J Aubé, RT Borchardt Advanced drug delivery reviews 27 (2-3), 235-256, 1997 | 307 | 1997 |
Intramolecular Schmidt reaction of alkyl azides J Aube, GL Milligan Journal of the American Chemical Society 113 (23), 8965-8966, 1991 | 285 | 1991 |
Chemistry of bridged lactams and related heterocycles M Szostak, J Aube Chemical reviews 113 (8), 5701-5765, 2013 | 247 | 2013 |
Intramolecular Schmidt reactions of alkyl azides with ketones: scope and stereochemical studies GL Milligan, CJ Mossman, J Aube Journal of the American Chemical Society 117 (42), 10449-10459, 1995 | 219 | 1995 |
Biased agonists of the kappa opioid receptor suppress pain and itch without causing sedation or dysphoria TF Brust, J Morgenweck, SA Kim, JH Rose, JL Locke, CL Schmid, L Zhou, ... Science signaling 9 (456), ra117-ra117, 2016 | 211 | 2016 |
HFIP in organic synthesis HF Motiwala, AM Armaly, JG Cacioppo, TC Coombs, KRK Koehn, ... Chemical Reviews 122 (15), 12544-12747, 2022 | 203 | 2022 |
Characterization of a Cdc42 protein inhibitor and its use as a molecular probe L Hong, SR Kenney, GK Phillips, D Simpson, CE Schroeder, J Nöth, ... Journal of Biological Chemistry 288 (12), 8531-8543, 2013 | 185 | 2013 |
Tumor suppressor TET2 promotes cancer immunity and immunotherapy efficacy Y Xu, L Lv, Y Liu, MD Smith, WC Li, X Tan, M Cheng, Z Li, M Bovino, ... The Journal of clinical investigation 129 (10), 4316-4331, 2019 | 169 | 2019 |
First asymmetric total synthesis of (+)-sparteine BT Smith, JA Wendt, J Aubé Organic Letters 4 (15), 2577-2579, 2002 | 169 | 2002 |
Advancing biological understanding and therapeutics discovery with small-molecule probes SL Schreiber, JD Kotz, M Li, J Aubé, CP Austin, JC Reed, H Rosen, ... Cell 161 (6), 1252-1265, 2015 | 164 | 2015 |
Intramolecular Friedel–Crafts acylation reaction promoted by 1, 1, 1, 3, 3, 3-hexafluoro-2-propanol HF Motiwala, RH Vekariya, J Aube Organic letters 17 (21), 5484-5487, 2015 | 158 | 2015 |
Syntheses of the Stemona Alkaloids (±)-Stenine, (±)-Neostenine, and (±)-13-Epineostenine Using a Stereodivergent Diels–Alder/Azido-Schmidt Reaction KJ Frankowski, JE Golden, Y Zeng, Y Lei, J Aubé Journal of the American Chemical Society 130 (18), 6018-6024, 2008 | 158 | 2008 |
Development of functionally selective, small molecule agonists at kappa opioid receptors L Zhou, KM Lovell, KJ Frankowski, SR Slauson, AM Phillips, JM Streicher, ... Journal of Biological Chemistry 288 (51), 36703-36716, 2013 | 154 | 2013 |
Identification and validation of novel small molecule disruptors of HuR-mRNA interaction X Wu, L Lan, DM Wilson, RT Marquez, W Tsao, P Gao, A Roy, BA Turner, ... ACS chemical biology 10 (6), 1476-1484, 2015 | 150 | 2015 |
A potent and selective inhibitor of Cdc42 GTPase Z Surviladze, A Waller, JJ Strouse, C Bologa, O Ursu, V Salas, ... Probe Reports from the NIH Molecular Libraries Program [Internet], 2010 | 148 | 2010 |
Reactions of alkyl azides and ketones as mediated by Lewis acids: Schmidt and Mannich reactions using azide precursors P Desai, K Schildknegt, KA Agrios, C Mossman, GL Milligan, J Aubé Journal of the American Chemical Society 122 (30), 7226-7232, 2000 | 147 | 2000 |
One-Step Conversion of Aldehydes to Oxazolines and 5,6-Dihydro-4H-1,3-oxazines Using 1,2- and 1,3-Azido Alcohols JG Badiang, J Aubé The Journal of Organic Chemistry 61 (7), 2484-2487, 1996 | 142 | 1996 |