Synthesis and biological activity of furoxan derivatives against Mycobacterium tuberculosis GF dos Santos Fernandes, PC de Souza, LB Marino, K Chegaev, ... European Journal of Medicinal Chemistry 123, 523-531, 2016 | 88 | 2016 |
Nitric oxide donor doxorubicins accumulate into doxorubicin-resistant human colon cancer cells inducing cytotoxicity K Chegaev, C Riganti, L Lazzarato, B Rolando, S Guglielmo, I Campia, ... ACS medicinal chemistry letters 2 (7), 494-497, 2011 | 80 | 2011 |
Folate-targeted liposomal nitrooxy-doxorubicin: An effective tool against P-glycoprotein-positive and folate receptor-positive tumors E Gazzano, B Rolando, K Chegaev, IC Salaroglio, J Kopecka, I Pedrini, ... Journal of controlled release 270, 37-52, 2018 | 76 | 2018 |
Mitochondrial-targeting nitrooxy-doxorubicin: a new approach to overcome drug resistance C Riganti, B Rolando, J Kopecka, I Campia, K Chegaev, L Lazzarato, ... Molecular pharmaceutics 10 (1), 161-174, 2013 | 73 | 2013 |
NO-donor phenols: a new class of products endowed with antioxidant and vasodilator properties D Boschi, GC Tron, L Lazzarato, K Chegaev, C Cena, A Di Stilo, M Giorgis, ... Journal of medicinal chemistry 49 (10), 2886-2897, 2006 | 72 | 2006 |
NO-donor COX-2 inhibitors. New nitrooxy-substituted 1, 5-diarylimidazoles endowed with COX-2 inhibitory and vasodilator properties K Chegaev, L Lazzarato, P Tosco, C Cena, E Marini, B Rolando, ... Journal of medicinal chemistry 50 (7), 1449-1457, 2007 | 70 | 2007 |
Design, synthesis, and characterization of N-oxide-containing heterocycles with in vivo sterilizing antitubercular activity GF dos Santos Fernandes, PC De Souza, E Moreno-Viguri, ... Journal of Medicinal Chemistry 60 (20), 8647-8660, 2017 | 65 | 2017 |
Phenylsulfonylfuroxans as modulators of multidrug-resistance-associated protein-1 and P-glycoprotein R Fruttero, M Crosetti, K Chegaev, S Guglielmo, A Gasco, F Berardi, ... Journal of medicinal chemistry 53 (15), 5467-5475, 2010 | 65 | 2010 |
H2S-Donating Doxorubicins May Overcome Cardiotoxicity and Multidrug Resistance K Chegaev, B Rolando, D Cortese, E Gazzano, I Buondonno, L Lazzarato, ... Journal of Medicinal Chemistry 59 (10), 4881-4889, 2016 | 59 | 2016 |
Leishmanicidal activities of novel synthetic furoxan and benzofuroxan derivatives LA Dutra, L de Almeida, TG Passalacqua, JS Reis, FAE Torres, I Martinez, ... Antimicrobial Agents and Chemotherapy 58 (8), 4837-4847, 2014 | 59 | 2014 |
Endoplasmic reticulum-targeting doxorubicin: a new tool effective against doxorubicin-resistant osteosarcoma I Buondonno, E Gazzano, E Tavanti, K Chegaev, J Kopecka, M Fanelli, ... Cellular and Molecular Life Sciences 76, 609-625, 2019 | 55 | 2019 |
Hyaluronated liposomes containing H2S-releasing doxorubicin are effective against P-glycoprotein-positive/doxorubicin-resistant osteosarcoma cells and xenografts E Gazzano, I Buondonno, A Marengo, B Rolando, K Chegaev, J Kopecka, ... Cancer Letters 456, 29-39, 2019 | 54 | 2019 |
Light-regulated NO release as a novel strategy to overcome doxorubicin multidrug resistance K Chegaev, A Fraix, E Gazzano, GEF Abd-Ellatef, M Blangetti, B Rolando, ... ACS Medicinal Chemistry Letters 8 (3), 361-365, 2017 | 49 | 2017 |
Edaravone derivatives containing NO-donor functions K Chegaev, C Cena, M Giorgis, B Rolando, P Tosco, M Bertinaria, ... Journal of Medicinal Chemistry 52 (2), 574-578, 2009 | 48 | 2009 |
Doxorubicin-antioxidant co-drugs K Chegaev, C Riganti, B Rolando, L Lazzarato, E Gazzano, S Guglielmo, ... Bioorganic & medicinal chemistry letters 23 (19), 5307-5310, 2013 | 47 | 2013 |
Furazan and furoxan sulfonamides are strong α-carbonic anhydrase inhibitors and potential antiglaucoma agents K Chegaev, L Lazzarato, Y Tamboli, D Boschi, M Blangetti, A Scozzafava, ... Bioorganic & Medicinal Chemistry 22 (15), 3913-3921, 2014 | 41 | 2014 |
New nitric oxide or hydrogen sulfide releasing aspirins L Lazzarato, K Chegaev, E Marini, B Rolando, E Borretto, S Guglielmo, ... Journal of medicinal chemistry 54 (15), 5478-5484, 2011 | 38 | 2011 |
(Nitrooxyacyloxy) methyl esters of aspirin as novel nitric oxide releasing aspirins L Lazzarato, M Donnola, B Rolando, K Chegaev, E Marini, C Cena, ... Journal of medicinal chemistry 52 (16), 5058-5068, 2009 | 38 | 2009 |
Synthesis of 2-monofunctionalized 2, 4, 6, 8-tetraazabicyclo [3.3. 0] octane-3, 7-diones AN Kravchenko, EY Maksareva, PA Belyakov, AS Sigachev, KY Chegaev, ... Russian chemical bulletin 52, 192-197, 2003 | 37 | 2003 |
New functional glycoluril derivatives KY Chegaev, AN Kravchenko, OV Lebedev, YA Strelenko Mendeleev Communications 11 (1), 32-33, 2001 | 37 | 2001 |