A key role for E-cadherin in intestinal homeostasis and Paneth cell maturation MR Schneider, M Dahlhoff, D Horst, B Hirschi, K Trülzsch, J Müller-Höcker, ... PloS one 5 (12), e14325, 2010 | 222 | 2010 |
Implementing tumor mutational burden (TMB) analysis in routine diagnostics—a primer for molecular pathologists and clinicians M Allgäuer, J Budczies, P Christopoulos, V Endris, A Lier, E Rempel, ... Translational lung cancer research 7 (6), 703, 2018 | 180 | 2018 |
Mitochondrial function controls intestinal epithelial stemness and proliferation E Berger, E Rath, D Yuan, N Waldschmitt, S Khaloian, M Allgäuer, ... Nature Communications 7, 2016 | 171 | 2016 |
Comprehensive genomic and transcriptomic analysis for guiding therapeutic decisions in patients with rare cancers P Horak, C Heining, S Kreutzfeldt, B Hutter, A Mock, J Hüllein, M Fröhlich, ... Cancer discovery 11 (11), 2780-2795, 2021 | 170 | 2021 |
Size matters: Dissecting key parameters for panel‐based tumor mutational burden analysis I Buchhalter, E Rempel, V Endris, M Allgäuer, O Neumann, AL Volckmar, ... International journal of cancer 144 (4), 848-858, 2019 | 163 | 2019 |
Optimizing panel-based tumor mutational burden (TMB) measurement J Budczies, M Allgäuer, K Litchfield, E Rempel, P Christopoulos, D Kazdal, ... Annals of Oncology 30 (9), 1496-1506, 2019 | 143 | 2019 |
Measurement of tumor mutational burden (TMB) in routine molecular diagnostics: in silico and real‐life analysis of three larger gene panels V Endris, I Buchhalter, M Allgäuer, E Rempel, A Lier, AL Volckmar, ... International journal of cancer 144 (9), 2303-2312, 2019 | 109 | 2019 |
Combined targeted DNA and RNA sequencing of advanced NSCLC in routine molecular diagnostics: Analysis of the first 3,000 Heidelberg cases AL Volckmar, J Leichsenring, M Kirchner, P Christopoulos, O Neumann, ... International journal of cancer 145 (3), 649-661, 2019 | 101 | 2019 |
Variant classification in precision oncology J Leichsenring, P Horak, S Kreutzfeldt, C Heining, P Christopoulos, ... International journal of cancer 145 (11), 2996-3010, 2019 | 100 | 2019 |
Intraductal tubulopapillary neoplasms of the bile ducts: clinicopathologic, immunohistochemical, and molecular analysis of 20 cases AM Schlitter, KT Jang, G Klöppel, B Saka, SM Hong, H Choi, GJ Offerhaus, ... Modern Pathology 28 (9), 1249-1264, 2015 | 100 | 2015 |
Spatial and Temporal Heterogeneity of Panel-Based Tumor Mutational Burden in Pulmonary Adenocarcinoma: Separating Biology From Technical Artifacts D Kazdal, V Endris, M Allgäuer, M Kriegsmann, J Leichsenring, ... Journal of thoracic oncology 14 (11), 1935-1947, 2019 | 92 | 2019 |
The E3 ligase RNF43 inhibits Wnt signaling downstream of mutated β-catenin by sequestering TCF4 to the nuclear membrane A Loregger, M Grandl, R Mejías-Luque, M Allgäuer, K Degenhart, ... Science Signaling, 2015 | 84 | 2015 |
Lymphocyte-driven regional immunopathology in pneumonitis caused by impaired central immune tolerance EMN Ferré, TJ Break, PD Burbelo, M Allgäuer, DE Kleiner, D Jin, Z Xu, ... Science translational medicine 11 (495), eaav5597, 2019 | 73 | 2019 |
Artificial intelligence and pathology: From principles to practice and future applications in histomorphology and molecular profiling A Stenzinger, M Alber, M Allgäuer, P Jurmeister, M Bockmayr, J Budczies, ... Seminars in cancer biology 84, 129-143, 2022 | 65 | 2022 |
A case of severe hyperaldosteronism caused by a de novo mutation affecting a critical salt bridge Kir3. 4 residue S Monticone, S Bandulik, J Stindl, M Zilbermint, I Dedov, P Mulatero, ... The Journal of Clinical Endocrinology & Metabolism 100 (1), E114-E118, 2015 | 54 | 2015 |
A gene expression signature associated with B cells predicts benefit from immune checkpoint blockade in lung adenocarcinoma J Budczies, M Kirchner, K Kluck, D Kazdal, J Glade, M Allgäuer, ... OncoImmunology 10 (1), 1860586, 2021 | 48 | 2021 |
RNA-Based Detection of Gene Fusions in Formalin-Fixed and Paraffin-Embedded Solid Cancer Samples M Kirchner, O Neumann, AL Volckmar, F Stögbauer, M Allgäuer, D Kazdal, ... Cancers 11 (9), 1309, 2019 | 48 | 2019 |
Antisense targeting of CD47 enhances human cytotoxic T-cell activity and increases survival of mice bearing B16 melanoma when combined with anti-CTLA4 and tumor irradiation AL Schwartz, PR Nath, M Allgauer, EC Lessey-Morillon, JM Sipes, ... Cancer Immunology, Immunotherapy 68, 1805-1817, 2019 | 46 | 2019 |
Detection of TP53 Mutations in Tissue or Liquid Rebiopsies at Progression Identifies ALK+ Lung Cancer Patients with Poor Survival P Christopoulos, S Dietz, M Kirchner, AL Volckmar, V Endris, O Neumann, ... Cancers 11 (1), 124, 2019 | 46 | 2019 |
Loss of endogenous RNF43 function enhances proliferation and tumour growth of intestinal and gastric cells V Neumeyer, M Grandl, A Dietl, A Brutau-Abia, M Allgäuer, B Kalali, ... Carcinogenesis 40 (4), 551-559, 2019 | 38 | 2019 |