Engineering the protein dynamics of an ancestral luciferase A Schenkmayerova, GP Pinto, M Toul, M Marek, L Hernychova, ... Nature Communications 12 (1), 3616, 2021 | 67 | 2021 |
Structural biology and protein engineering of thrombolytics J Mican, M Toul, D Bednar, J Damborsky Computational and structural biotechnology journal 17, 917-938, 2019 | 61 | 2019 |
Light-Emitting Dehalogenases: Reconstruction of Multifunctional Biocatalysts R Chaloupkova, V Liskova, M Toul, K Markova, E Sebestova, ... ACS Catalysis 9 (6), 4810-4823, 2019 | 44 | 2019 |
Catalytic mechanism for Renilla-type luciferases A Schenkmayerova, M Toul, D Pluskal, R Baatallah, G Gagnot, GP Pinto, ... Nature Catalysis 6 (1), 23-38, 2023 | 26 | 2023 |
Development and Testing of Thrombolytics in Stroke D Nikitin, S Choi, J Mican, M Toul, WS Ryu, J Damborsky, R Mikulik, ... Journal of Stroke 23 (1), 12-36, 2021 | 24 | 2021 |
Extended mechanism of the plasminogen activator staphylokinase revealed by global kinetic analysis: 1000-fold higher catalytic activity than That of clinically used alteplase M Toul, D Nikitin, M Marek, J Damborsky, Z Prokop ACS Catalysis 12 (7), 3807-3814, 2022 | 8 | 2022 |
Illuminating the mechanism and allosteric behavior of NanoLuc luciferase M Nemergut, D Pluskal, J Horackova, T Sustrova, J Tulis, T Barta, ... Nature Communications 14 (1), 7864, 2023 | 5 | 2023 |
Hidden Potential of Highly Efficient and Widely Accessible Thrombolytic Staphylokinase M Toul, J Mican, V Slonkova, D Nikitin, M Marek, D Bednar, J Damborsky, ... Stroke 53 (10), 3235-3237, 2022 | 5 | 2022 |
Computer-aided engineering of staphylokinase toward enhanced affinity and selectivity for plasmin D Nikitin, J Mican, M Toul, D Bednar, M Peskova, P Kittova, S Thalerova, ... Computational and structural biotechnology journal 20, 1366-1377, 2022 | 5 | 2022 |
Identification, characterization, and engineering of glycosylation in thrombolytics M Toul, V Slonkova, J Mican, A Urminsky, M Tomkova, E Sedlak, ... Biotechnology Advances 66, 108174, 2023 | 3 | 2023 |
ENGINEERING NON-IMMUNOGENIC STAPHYLOKINASE VARIANTS WITH IMPROVED THROMBOLYSIS FOR ACUTE ISCHEMIC STROKE V Slonkova, M Toul, J Mican, A Strunga, L Kasiarova, D Nikitin, ... INTERNATIONAL JOURNAL OF STROKE 18 (3), 351-351, 2023 | | 2023 |
FIBRIN SELECTIVE ALTEPLASE WITH IMPROVED THROMBOLYSIS AND INHIBITION RESISTANCE ENGINEERED BY RATIONAL DESIGN V Slonkova, M Toul, J Mican, M Marek, D Bednar, R Mikulik, J Vitecek, ... INTERNATIONAL JOURNAL OF STROKE 18 (3), 350-351, 2023 | | 2023 |
Catalytic mechanism for Renilla-type luciferases A Smith, M Toul, D Pluskal, R Baatallah, G Gagnot, ... | | 2023 |
Poměr plazminogen/plazmin jako ukazatel bezpečnosti trombolytické léčby E Brhelová, V Slonková, M Toul, D Kovář, S Thalerová, J Hložková, ... | | 2023 |
IMPACT OF ADMINISTRATION METHOD OF THROMBOLYTICS ON THEIR THROMBOLYTIC EFFECTS AD Aksu, J Hložková, P Scheer, E Brhelová, J Mičan, M Toul, ... | | 2022 |
Engineering protein dynamics for the understanding of divergent evolution of the Renilla luciferase M Toul, A Smith, JG Rangel Pamplona Pizarro Pinto, M Marek, ... | | 2021 |
Functional switching based on altered enzyme flexibility via InDel mutagenesis of a reconstructed ancestor A Schenkmayerova, G Pinto, M Marek, M Toul, L Hernychová, V Liskova, ... Journal of Biotechnology 305, S32, 2019 | | 2019 |
Kinetic mechanism of coelenterazine-dependent luciferase reaction M Toul Masaryk University, Faculty of Science, 2018 | | 2018 |
Rational Protein Design Driven by Kinetic Studies M TOUL | | |
Kinetický mechanismus koelenterazin-dependentní luciferasové reakce M Toul | | |