| Whole-genome sequencing reveals host factors underlying critical COVID-19 A Kousathanas, E Pairo-Castineira, K Rawlik, A Stuckey, CA Odhams, ... Nature 607 (7917), 97-103, 2022 | 305 | 2022 |
| The PI3K/AKT/c-MYC axis promotes the acquisition of cancer stem-like features in esophageal squamous cell carcinoma HF Zhang, C Wu, A Alshareef, N Gupta, Q Zhao, XE Xu, JW Jiao, EM Li, ... Stem cells 34 (8), 2040-2051, 2016 | 85 | 2016 |
| Rare loss-of-function variants in type I IFN immunity genes are not associated with severe COVID-19 G Povysil, G Butler-Laporte, N Shang, C Wang, A Khan, M Alaamery, ... The Journal of clinical investigation 131 (14), 2021 | 76 | 2021 |
| The opposing function of STAT3 as an oncoprotein and tumor suppressor is dictated by the expression status of STAT3β in esophageal squamous cell carcinoma HF Zhang, Y Chen, C Wu, ZY Wu, DJ Tweardy, A Alshareef, LD Liao, ... Clinical Cancer Research 22 (3), 691-703, 2016 | 61 | 2016 |
| The use of cellular thermal shift assay (CETSA) to study Crizotinib resistance in ALK-expressing human cancers A Alshareef, HF Zhang, YH Huang, C Wu, JD Zhang, P Wang, ... Scientific reports 6 (1), 33710, 2016 | 54 | 2016 |
| Loss of miR-200b promotes invasion via activating the Kindlin-2/integrin β1/AKT pathway in esophageal squamous cell carcinoma: An E-cadherin-independent mechanism HF Zhang, A Alshareef, C Wu, S Li, JW Jiao, HH Cao, R Lai, LY Xu, EM Li Oncotarget 6 (30), 28949, 2015 | 45 | 2015 |
| SARS-CoV-2 susceptibility and COVID-19 disease severity are associated with genetic variants affecting gene expression in a variety of tissues M D’Antonio, JP Nguyen, TD Arthur, H Matsui, BM Neale, M Daly, ... Cell reports 37 (7), 2021 | 39 | 2021 |
| Hypoxia induces the acquisition of cancer stem-like phenotype via upregulation and activation of signal transducer and activator of transcription-3 (STAT3) in MDA-MB-231, a … H Soleymani Abyaneh, N Gupta, A Alshareef, K Gopal, A Lavasanifar, ... Cancer Microenvironment 11 (2), 141-152, 2018 | 38 | 2018 |
| A positive feedback loop involving the Wnt/β-catenin/MYC/Sox2 axis defines a highly tumorigenic cell subpopulation in ALK-positive anaplastic large cell lymphoma C Wu, HF Zhang, N Gupta, A Alshareef, Q Wang, YH Huang, JT Lewis, ... Journal of hematology & oncology 9, 1-14, 2016 | 38 | 2016 |
| miR-200b induces cell cycle arrest and represses cell growth in esophageal squamous cell carcinoma HF Zhang, A Alshareef, C Wu, JW Jiao, PH Sorensen, R Lai, LY Xu, EM Li Carcinogenesis 37 (9), 858-869, 2016 | 38 | 2016 |
| Oxidative stress induces the acquisition of cancer stem-like phenotype in breast cancer detectable by using a Sox2 regulatory region-2 (SRR2) reporter K Gopal, N Gupta, H Zhang, A Alshareef, H Alqahtani, G Bigras, J Lewis, ... Oncotarget 7 (3), 3111, 2015 | 37 | 2015 |
| DDX17 (P72), a Sox2 binding partner, promotes stem-like features conferred by Sox2 in a small cell population in estrogen receptor-positive breast cancer H Alqahtani, K Gopal, N Gupta, K Jung, A Alshareef, X Ye, F Wu, L Li, ... Cellular signalling 28 (2), 42-50, 2016 | 36 | 2016 |
| High Myc expression and transcription activity underlies intra-tumoral heterogeneity in triple-negative breast cancer N Gupta, K Jung, C Wu, A Alshareef, H Alqahtani, S Damaraju, ... Oncotarget 8 (17), 28101, 2017 | 35 | 2017 |
| STAT1 is phosphorylated and downregulated by the oncogenic tyrosine kinase NPM-ALK in ALK-positive anaplastic large-cell lymphoma C Wu, O Molavi, H Zhang, N Gupta, A Alshareef, KM Bone, K Gopal, F Wu, ... Blood, The Journal of the American Society of Hematology 126 (3), 336-345, 2015 | 30 | 2015 |
| Triple negative breast cancers comprise a highly tumorigenic cell subpopulation detectable by its high responsiveness to a Sox2 regulatory region 2 (SRR2) reporter K Jung, N Gupta, P Wang, JT Lewis, K Gopal, F Wu, X Ye, A Alshareef, ... Oncotarget 6 (12), 10366, 2015 | 29 | 2015 |
| Oxidative stress enhances tumorigenicity and stem-like features via the activation of the Wnt/β-catenin/MYC/Sox2 axis in ALK-positive anaplastic large-cell lymphoma C Wu, N Gupta, YH Huang, HF Zhang, A Alshareef, A Chow, R Lai BMC cancer 18, 1-11, 2018 | 26 | 2018 |
| Constitutive activation of STAT3 in myeloma cells cultured in a three-dimensional, reconstructed bone marrow model YH Huang, O Molavi, A Alshareef, M Haque, Q Wang, MP Chu, ... Cancers 10 (6), 206, 2018 | 26 | 2018 |
| Micellar nano-carriers for the delivery of STAT3 dimerization inhibitors to melanoma AH Soleimani, SM Garg, IM Paiva, MR Vakili, A Alshareef, YH Huang, ... Drug delivery and translational research 7, 571-581, 2017 | 26 | 2017 |
| Profiling gene promoter occupancy of Sox2 in two phenotypically distinct breast cancer cell subsets using chromatin immunoprecipitation and genome-wide promoter microarrays K Jung, P Wang, N Gupta, K Gopal, F Wu, X Ye, A Alshareef, G Bigras, ... Breast Cancer Research 16, 1-13, 2014 | 17 | 2014 |
| Disheveled proteins promote cell growth and tumorigenicity in ALK-positive anaplastic large cell lymphoma SA Hegazy, A Alshareef, P Gelebart, M Anand, H Armanious, RJ Ingham, ... Cellular signalling 25 (1), 295-307, 2013 | 16 | 2013 |
