Ataxin-2 intermediate-length polyglutamine expansions are associated with increased risk for ALS AC Elden, HJ Kim, MP Hart, AS Chen-Plotkin, BS Johnson, X Fang, ... Nature 466 (7310), 1069-1075, 2010 | 1412 | 2010 |
Molecular determinants and genetic modifiers of aggregation and toxicity for the ALS disease protein FUS/TLS Z Sun, Z Diaz, X Fang, MP Hart, A Chesi, J Shorter, AD Gitler PLoS biology 9 (4), e1000614, 2011 | 516 | 2011 |
A yeast functional screen predicts new candidate ALS disease genes J Couthouis, MP Hart, J Shorter, M DeJesus-Hernandez, R Erion, ... Proceedings of the National Academy of Sciences 108 (52), 20881-20890, 2011 | 447 | 2011 |
Evaluating the role of the FUS/TLS-related gene EWSR1 in amyotrophic lateral sclerosis J Couthouis, MP Hart, R Erion, OD King, Z Diaz, T Nakaya, F Ibrahim, ... Human molecular genetics 21 (13), 2899-2911, 2012 | 304 | 2012 |
Inhibition of monocarboxylate transporter 2 in the retrotrapezoid nucleus in rats: a test of the astrocyte–neuron lactate-shuttle hypothesis JS Erlichman, A Hewitt, TL Damon, M Hart, J Kurascz, A Li, JC Leiter Journal of Neuroscience 28 (19), 4888-4896, 2008 | 133 | 2008 |
ALS-associated ataxin 2 polyQ expansions enhance stress-induced caspase 3 activation and increase TDP-43 pathological modifications MP Hart, AD Gitler Journal of Neuroscience 32 (27), 9133-9142, 2012 | 102 | 2012 |
Fragile X protein mitigates TDP-43 toxicity by remodeling RNA granules and restoring translation AN Coyne, SB Yamada, BB Siddegowda, PS Estes, BL Zaepfel, ... Human molecular genetics 24 (24), 6886-6898, 2015 | 88 | 2015 |
Neurexin controls plasticity of a mature, sexually dimorphic neuron MP Hart, O Hobert Nature 553 (7687), 165-170, 2018 | 76 | 2018 |
Diversification of C. elegans motor neuron identity via selective effector gene repression SY Kerk, P Kratsios, M Hart, R Mourao, O Hobert Neuron 93 (1), 80-98, 2017 | 64 | 2017 |
Evaluating the prevalence of polyglutamine repeat expansions in amyotrophic lateral sclerosis T Lee, YR Li, A Chesi, MP Hart, D Ramos, N Jethava, D Hosangadi, ... Neurology 76 (24), 2062-2065, 2011 | 64 | 2011 |
TDP-43 toxicity in yeast M Armakola, MP Hart, AD Gitler Methods 53 (3), 238-245, 2011 | 57 | 2011 |
Distinct TDP-43 pathology in ALS patients with ataxin 2 intermediate-length polyQ expansions MP Hart, J Brettschneider, VMY Lee, JQ Trojanowski, AD Gitler Acta neuropathologica 124, 221-230, 2012 | 47 | 2012 |
Synaptic dysfunction connects autism spectrum disorder and sleep disturbances: A perspective from studies in model organisms F Doldur-Balli, T Imamura, OJ Veatch, NN Gong, DC Lim, MP Hart, T Abel, ... Sleep medicine reviews 62, 101595, 2022 | 18 | 2022 |
A yeast model for polyalanine-expansion aggregation and toxicity CA Konopka, MN Locke, PS Gallagher, N Pham, MP Hart, CJ Walker, ... Molecular biology of the cell 22 (12), 1971-1984, 2011 | 17 | 2011 |
Stress-Induced Neuron Remodeling Reveals Differential Interplay Between Neurexin and Environmental Factors in Caenorhabditis elegans MP Hart Genetics 213 (4), 1415-1430, 2019 | 14 | 2019 |
Sexual dimorphism: Mystery neurons control sex-specific behavioral plasticity MP Hart, O Hobert Current Biology 25 (24), R1170-R1172, 2015 | 6 | 2015 |
Mice expressing mutant parkin exhibit hallmark features of Parkinson's disease MP Hart, A Xu Journal of Neuroscience 29 (23), 7392-7394, 2009 | 4 | 2009 |
CAJAL enables analysis and integration of single-cell morphological data using metric geometry KW Govek, P Nicodemus, Y Lin, J Crawford, AB Saturnino, H Cui, K Zoga, ... Nature Communications 14 (1), 3672, 2023 | 3 | 2023 |
Distinct neurexin isoforms cooperate to initiate and maintain foraging activity BL Bastien, MH Cowen, MP Hart Translational Psychiatry 13 (1), 367, 2023 | 1 | 2023 |
Neurexin drives C. elegans avoidance behavior independently of its post-synaptic binding partner Neuroligin CS Muirhead, KC Reddy, S Guerra, M Rieger, MP Hart, J Srinivasan, ... G3: Genes, Genomes, Genetics, jkae111, 2024 | | 2024 |