Mapping the human genetic architecture of COVID-19 MEK Niemi, J Karjalainen, RG Liao, BM Neale, M Daly, A Ganna, ... Nature 600, 472-477, 2021 | 756* | 2021 |
Aptamers chemistry: Chemical modifications and conjugation strategies F Odeh, H Nsairat, W Alshaer, MA Ismail, E Esawi, B Qaqish, AA Bawab, ... Molecules 25 (1), 3, 2019 | 300 | 2019 |
Global Biobank Meta-analysis Initiative: Powering genetic discovery across human disease W Zhou, M Kanai, KHH Wu, H Rasheed, K Tsuo, JB Hirbo, Y Wang, ... Cell Genomics 2 (10), 2022 | 215 | 2022 |
Thymoquinone in liposomes: a study of loading efficiency and biological activity towards breast cancer F Odeh, SI Ismail, R Abu-Dahab, IS Mahmoud, A Al Bawab Drug delivery 19 (8), 371-377, 2012 | 212 | 2012 |
Functionalizing liposomes with anti-CD44 aptamer for selective targeting of cancer cells W Alshaer, H Hillaireau, J Vergnaud, S Ismail, E Fattal Bioconjugate chemistry 26 (7), 1307-1313, 2015 | 188 | 2015 |
Aptamer-guided siRNA-loaded nanomedicines for systemic gene silencing in CD-44 expressing murine triple-negative breast cancer model W Alshaer, H Hillaireau, J Vergnaud, S Mura, C Deloménie, F Sauvage, ... Journal of controlled release 271, 98-106, 2018 | 119 | 2018 |
Transcriptional networks and cellular senescence in human mammary fibroblasts K Hardy, L Mansfield, A Mackay, S Benvenuti, S Ismail, P Arora, ... Molecular biology of the cell 16 (2), 943-953, 2005 | 105 | 2005 |
SARS-CoV-2 entry in host cells-multiple targets for treatment and prevention IS Mahmoud, YB Jarrar, W Alshaer, S Ismail Biochimie 175, 93-98, 2020 | 99 | 2020 |
In Vitro Selection of Modified RNA Aptamers Against CD44 Cancer Stem Cell Marker N Ababneh, W Alshaer, O Al-Louzi, A Mahafzah, M El-Khateeb, ... Nucleic acid therapeutics 23 (6), 401-407, 2013 | 84 | 2013 |
One year of SARS-CoV-2: genomic characterization of COVID-19 outbreak in Qatar FM Benslimane, HA Al Khatib, O Al-Jamal, D Albatesh, S Boughattas, ... Frontiers in cellular and infection microbiology 11, 768883, 2021 | 70 | 2021 |
Rare loss-of-function variants in type I IFN immunity genes are not associated with severe COVID-19 G Povysil, G Butler-Laporte, N Shang, C Wang, A Khan, M Alaamery, ... The Journal of clinical investigation 131 (14), 2021 | 69 | 2021 |
Allele and genotype frequencies of the polymorphic cytochrome P450 genes (CYP1A1, CYP3A4, CYP3A5, CYP2C9 and CYP2C19) in the Jordanian population AM Yousef, NR Bulatova, W Newman, N Hakooz, S Ismail, H Qusa, ... Molecular biology reports 39, 9423-9433, 2012 | 67 | 2012 |
Incidence of bcr-abl fusion transcripts in healthy individuals SI Ismail, RG Naffa, AMF Yousef, MT Ghanim Molecular Medicine Reports 9 (4), 1271-1276, 2014 | 64 | 2014 |
Cancer incidence in Jordan from 1996 to 2009-a comprehensive study SI Ismail, M Soubani, JM Nimri, AH Al-Zeer Asian Pacific Journal of Cancer Prevention 14 (6), 3527-3534, 2013 | 62 | 2013 |
Meta-analysis fine-mapping is often miscalibrated at single-variant resolution M Kanai, R Elzur, W Zhou, KHH Wu, H Rasheed, K Tsuo, JB Hirbo, ... Cell genomics 2 (12), 2022 | 54 | 2022 |
Protective Role of a TMPRSS2 Variant on Severe COVID-19 Outcome in Young Males and Elderly Women M Monticelli, B Hay Mele, E Benetti, C Fallerini, M Baldassarri, S Furini, ... Genes 12 (4), 596, 2021 | 50 | 2021 |
Qatar Genome: insights on genomics from the Middle East H Mbarek, GD Gandhi, S Selvaraj, W Al-Muftah, R Badji, Y Al-Sarraj, ... medRxiv, 2021 | 50 | 2021 |
Therapeutic aptamers in discovery, preclinical and clinical stages SI Ismail, W Alshaer Advanced drug delivery reviews 134, 51-64, 2018 | 49 | 2018 |
Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk N Shrine, AG Izquierdo, J Chen, R Packer, RJ Hall, AL Guyatt, C Batini, ... Nature genetics 55 (3), 410-422, 2023 | 46 | 2023 |
Remote loading of curcumin-in-modified β-cyclodextrins into liposomes using a transmembrane pH gradient F Odeh, H Nsairat, W Alshaer, S Alsotari, R Buqaien, S Ismail, A Awidi, ... RSC advances 9 (64), 37148-37161, 2019 | 45 | 2019 |