Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing BW Kunkle, B Grenier-Boley, R Sims, JC Bis, V Damotte, AC Naj, ... Nature genetics 51 (3), 414-430, 2019 | 2293 | 2019 |
New insights into the genetic etiology of Alzheimer’s disease and related dementias C Bellenguez, F Küçükali, IE Jansen, L Kleineidam, S Moreno-Grau, ... Nature genetics 54 (4), 412-436, 2022 | 1049 | 2022 |
Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease R Sims, SJ Van Der Lee, AC Naj, C Bellenguez, N Badarinarayan, ... Nature genetics 49 (9), 1373-1384, 2017 | 926 | 2017 |
Altered Bile Acid Profile Associates with Cognitive Impairment in Alzheimer's Disease: An Emerging Role for Gut Microbiome S Mahmoudiandehkordi, M Arnold, K Nho, S Ahmad, W Jia, G Xia, ... Alzheimer's & Dementia, 2019, 281956, 2018 | 498 | 2018 |
Altered Bile Acid Profile in Mild Cognitive Impairment and Alzheimer's Disease: Relationship to Neuroimaging and CSF Biomarkers K Nho, A Kueider-Paisley, S MahmoudianDehkord, M Arnold, ... Alzheimer's & Dementia, 2019, 284141, 2018 | 248 | 2018 |
Whole exome sequencing study identifies novel rare and common Alzheimer’s-Associated variants involved in immune response and transcriptional regulation JC Bis, X Jian, BW Kunkle, Y Chen, KL Hamilton-Nelson, WS Bush, ... Molecular psychiatry 25 (8), 1859-1875, 2020 | 244 | 2020 |
Association of altered liver enzymes with Alzheimer disease diagnosis, cognition, neuroimaging measures, and cerebrospinal fluid biomarkers K Nho, A Kueider-Paisley, S Ahmad, S MahmoudianDehkordi, M Arnold, ... JAMA network open 2 (7), e197978-e197978, 2019 | 177 | 2019 |
Genetic predisposition, modifiable-risk-factor profile and long-term dementia risk in the general population S Licher, S Ahmad, H Karamujić-Čomić, T Voortman, MJG Leening, ... Nature medicine 25 (9), 1364-1369, 2019 | 174 | 2019 |
Increased high-density lipoprotein levels associated with age-related macular degeneration: evidence from the EYE-RISK and European Eye Epidemiology Consortia JM Colijn, AI den Hollander, A Demirkan, A Cougnard-Grégoire, ... Ophthalmology 126 (3), 393-406, 2019 | 112 | 2019 |
Genetic correlations and genome-wide associations of cortical structure in general population samples of 22,824 adults E Hofer, GV Roshchupkin, HHH Adams, MJ Knol, H Lin, S Li, H Zare, ... Nature communications 11 (1), 4796, 2020 | 84 | 2020 |
Exome sequencing identifies rare damaging variants in ATP8B4 and ABCA1 as risk factors for Alzheimer’s disease H Holstege, M Hulsman, C Charbonnier, B Grenier-Boley, O Quenez, ... Nature genetics 54 (12), 1786-1794, 2022 | 82 | 2022 |
Alzheimer Disease Genetics Consortium (ADGC); European Alzheimer’s Disease Initiative (EADI); Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium (CHARGE … BW Kunkle, B Grenier-Boley, R Sims, JC Bis, V Damotte, AC Naj, ... Nat Genet 51 (3), 414-430, 2019 | 79 | 2019 |
New insights on the genetic etiology of Alzheimer’s and related dementia C Bellenguez, F Küçükali, I Jansen, V Andrade, S Moreno-Grau, N Amin, ... MedRxiv, 2020.10. 01.20200659, 2020 | 73 | 2020 |
Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume D Vojinovic, HH Adams, X Jian, Q Yang, AV Smith, JC Bis, A Teumer, ... Nature communications 9 (1), 3945, 2018 | 43 | 2018 |
Disentangling the biological pathways involved in early features of Alzheimer's disease in the Rotterdam Study S Ahmad, C Bannister, SJ van der Lee, D Vojinovic, HHH Adams, ... Alzheimer's & Dementia 14 (7), 848-857, 2018 | 40 | 2018 |
Exome sequencing identifies rare damaging variants in the ATB8B4 and ABCA1 genes as novel risk factors for Alzheimer’s disease H Holstege, M Hulsman, C Charbonnier, B Grenier‐Boley, O Quenez, ... Alzheimer's & Dementia 17, e055982, 2021 | 25 | 2021 |
Multiomics integrative analysis identifies APOE allele-specific blood biomarkers associated to Alzheimer’s disease etiopathogenesis L Madrid, S Moreno-Grau, S Ahmad, A González-Pérez, I de Rojas, R Xia, ... Aging (Albany NY) 13 (7), 9277, 2021 | 22 | 2021 |
Matrix metalloproteinase 10 is linked to the risk of progression to dementia of the Alzheimer’s type PV Martino Adami, A Orellana, P García, L Kleineidam, E Alarcón-Martín, ... Brain 145 (7), 2507-2517, 2022 | 21 | 2022 |
Genetic determinants of cortical structure (thickness, surface area and volumes) among disease free adults in the CHARGE Consortium E Hofer, GV Roshchupkin, HHH Adams, MJ Knol, H Lin, S Li, H Zare, ... BioRxiv, 409649, 2018 | 21 | 2018 |
Circulating metabolome and white matter hyperintensities in women and men E Sliz, J Shin, S Ahmad, DM Williams, S Frenzel, F Gauß, SE Harris, ... Circulation 145 (14), 1040-1052, 2022 | 20 | 2022 |