The Caucasus as an asymmetric semipermeable barrier to ancient human migrations B Yunusbayev, M Metspalu, M Järve, I Kutuev, S Rootsi, E Metspalu, ... Molecular biology and evolution 29 (1), 359-365, 2012 | 253 | 2012 |
miR-1, miR-10b, miR-155, and miR-191 are novel regulators of BDNF K Varendi, A Kumar, MA Härma, JO Andressoo Cellular and molecular life sciences 71, 4443-4456, 2014 | 172 | 2014 |
Distinguishing the co-ancestries of haplogroup G Y-chromosomes in the populations of Europe and the Caucasus S Rootsi, NM Myres, AA Lin, M Järve, RJ King, I Kutuev, VM Cabrera, ... European journal of human genetics 20 (12), 1275-1282, 2012 | 136 | 2012 |
GDNF overexpression from the native locus reveals its role in the nigrostriatal dopaminergic system function A Kumar, J Kopra, K Varendi, LL Porokuokka, A Panhelainen, S Kuure, ... PLoS genetics 11 (12), e1005710, 2015 | 123 | 2015 |
GDNF is not required for catecholaminergic neuron survival in vivo J Kopra, C Vilenius, S Grealish, MA Härma, K Varendi, J Lindholm, ... Nature neuroscience 18 (3), 319-322, 2015 | 72 | 2015 |
Dampened amphetamine-stimulated behavior and altered dopamine transporter function in the absence of brain GDNF JJ Kopra, A Panhelainen, S af Bjerkén, LL Porokuokka, K Varendi, S Olfat, ... Journal of Neuroscience 37 (6), 1581-1590, 2017 | 44 | 2017 |
From microRNA target validation to therapy: lessons learned from studies on BDNF K Varendi, K Mätlik, JO Andressoo Cellular and molecular life sciences 72, 1779-1794, 2015 | 39 | 2015 |
Short-term preoperative dietary restriction is neuroprotective in a rat focal stroke model K Varendi, M Airavaara, J Anttila, S Vose, A Planken, M Saarma, ... PloS one 9 (4), e93911, 2014 | 38 | 2014 |
Two-fold elevation of endogenous GDNF levels in mice improves motor coordination without causing side-effects K Mätlik, V Võikar, C Vilenius, N Kulesskaya, JO Andressoo Scientific Reports 8 (1), 11861, 2018 | 31 | 2018 |
Role of glial-cell-derived neurotrophic factor in salivary gland stem cell response to irradiation X Peng, K Varendi, M Maimets, JO Andressoo, RP Coppes Radiotherapy and Oncology 124 (3), 448-454, 2017 | 20 | 2017 |
Elevated endogenous GDNF induces altered dopamine signalling in mice and correlates with clinical severity in schizophrenia K Mätlik, DR Garton, AR Montaño-Rodríguez, S Olfat, F Eren, L Casserly, ... Molecular Psychiatry 27 (8), 3247-3261, 2022 | 17 | 2022 |
Increased endogenous GDNF in mice protects against age-related decline in neuronal cholinergic markers S Mitra, G Turconi, T Darreh-Shori, K Mätlik, M Aquilino, M Eriksdotter, ... Frontiers in aging neuroscience 13, 714186, 2021 | 12 | 2021 |
Postnatal prolongation of mammalian nephrogenesis by excess fetal GDNF H Li, K Kurtzeborn, J Kupari, Y Gui, E Siefker, B Lu, K Mätlik, S Olfat, ... Development 148 (10), dev197475, 2021 | 11 | 2021 |
Tristetraprolin is a novel regulator of BDNF A Kumar, K Varendi, J Peränen, JO Andressoo SpringerPlus 3, 1-10, 2014 | 11 | 2014 |
Histone bivalency regulates the timing of cerebellar granule cell development K Mätlik, EE Govek, MR Paul, CD Allis, ME Hatten Genes & Development 37 (13-14), 570-589, 2023 | 5 | 2023 |
Increased Physiological GDNF Levels Have No Effect on Dopamine Neuron Protection and Restoration in a Proteasome Inhibition Mouse Model of Parkinson’s Disease S Olfat, K Mätlik, JJ Kopra, DR Garton, VH Iivanainen, D Bhattacharya, ... Eneuro 10 (2), 2023 | 4 | 2023 |
Gene Knock Up via 3’UTR editing to study gene function in vivo K Mätlik, S Olfat, DR Garton, A Montaño-Rodriguez, G Turconi, ... bioRxiv, 775031, 2019 | 4 | 2019 |
Nicotinamide riboside alleviates Parkinson’s disease symptoms but downregulates dopamine metabolism upon lactacystin-induced proteostasis failure G Turconi, F Alam, T SenGupta, S Pirnes-Karhu, S Olfat, MS Schmidt, ... bioRxiv, 2021.03. 12.435062, 2021 | 2 | 2021 |
In vivo modulation of endogenous gene expression via CRISPR/Cas9-mediated 3’UTR editing K Mätlik, S Olfat, MC Cowlishaw, ED Moreno, S Ollila, JO Andressoo Heliyon 9 (3), 2023 | 1 | 2023 |
Correction: GDNF overexpression from the native locus reveals its role in the Nigrostriatal dopaminergic system function A Kumar, J Kopra, K Varendi, LL Porokuokka, A Panhelainen, S Kuure, ... Plos Genetics 12 (1), e1005808, 2016 | 1 | 2016 |