Molecular determinants of BK channel functional diversity and functioning R Latorre, K Castillo, W Carrasquel-Ursulaez, RV Sepulveda, ... Physiological reviews 97 (1), 39-87, 2016 | 249 | 2016 |
Molecular determinants of phosphatidylinositol 4, 5-bisphosphate (PI (4, 5) P2) binding to transient receptor potential V1 (TRPV1) channels H Poblete, I Oyarzún, P Olivero, J Comer, M Zuñiga, RV Sepulveda, ... Journal of Biological Chemistry 290 (4), 2086-2098, 2015 | 80 | 2015 |
Structural determinants of 5′, 6′-epoxyeicosatrienoic acid binding to and activation of TRPV4 channel A Berna-Erro, M Izquierdo-Serra, RV Sepúlveda, F Rubio-Moscardo, ... Scientific reports 7 (1), 10522, 2017 | 73 | 2017 |
Pore dimensions and the role of occupancy in unitary conductance of Shaker K channels I Díaz-Franulic, RV Sepúlveda, N Navarro-Quezada, F González-Nilo, ... Journal of General Physiology 146 (2), 133-146, 2015 | 31 | 2015 |
Structure-driven pharmacology of transient receptor potential channel vanilloid 1 I Díaz-Franulic, J Caceres-Molina, RV Sepulveda, F Gonzalez-Nilo, ... Molecular pharmacology 90 (3), 300-308, 2016 | 25 | 2016 |
Interaction between the linker, pre-S1, and TRP domains determines folding, assembly, and trafficking of TRPV channels A Garcia-Elias, A Berna-Erro, F Rubio-Moscardo, C Pardo-Pastor, ... Structure 23 (8), 1404-1413, 2015 | 25 | 2015 |
Hydrophobic interaction between contiguous residues in the S6 transmembrane segment acts as a stimuli integration node in the BK channel W Carrasquel-Ursulaez, GF Contreras, RV Sepúlveda, D Aguayo, ... Journal of General Physiology 145 (1), 61-74, 2015 | 18 | 2015 |
The molecular nature of the 17β-Estradiol binding site in the voltage-and Ca 2+-activated K+(BK) channel β1 subunit ST Granados, K Castillo, F Bravo-Moraga, RV Sepúlveda, ... Scientific Reports 9 (1), 9965, 2019 | 17 | 2019 |
β1-subunit–induced structural rearrangements of the Ca2+-and voltage-activated K+ (BK) channel JP Castillo, JE Sánchez-Rodríguez, HC Hyde, CA Zaelzer, D Aguayo, ... Proceedings of the National Academy of Sciences 113 (23), E3231-E3239, 2016 | 16 | 2016 |
Novel TRPV1 channel agonists with faster and more potent analgesic properties than capsaicin Y Duarte, J Cáceres, RV Sepúlveda, D Arriagada, P Olivares, ... Frontiers in Pharmacology 11, 1040, 2020 | 15 | 2020 |
Increasing the intracellular isoprenoid pool in Saccharomyces cerevisiae by structural fine-tuning of a bifunctional farnesyl diphosphate synthase S Rubat, I Varas, R Sepúlveda, D Almonacid, F González-Nilo, E Agosin FEMS Yeast Research 17 (4), 2017 | 12 | 2017 |
K+ conduction and Mg2+ blockade in a shaker Kv-channel single point mutant with an unusually high conductance C Moscoso, A Vergara-Jaque, V Márquez-Miranda, RV Sepúlveda, ... Biophysical journal 103 (6), 1198-1207, 2012 | 11 | 2012 |
Heterologous expression, purification and characterization of three novel esterases secreted by the lignocellulolytic fungus Penicillium purpurogenum when grown on sugar beet pulp G Oleas, E Callegari, R Sepúlveda, J Eyzaguirre Carbohydrate research 443, 42-48, 2017 | 6 | 2017 |
Unveiling Novel Urease Inhibitors for Helicobacter pylori: A Multi-Methodological Approach from Virtual Screening and ADME to Molecular Dynamics Simulations P Valenzuela-Hormazabal, RV Sepúlveda, M Alegría-Arcos, ... International Journal of Molecular Sciences 25 (4), 1968, 2024 | 2 | 2024 |
The Emergence of New Catalytic Abilities in an Endoxylanase from Family GH10 by Removing an Intrinsically Disordered Region C Gil-Durán, RV Sepúlveda, M Rojas, V Castro-Fernández, V Guixé, ... International Journal of Molecular Sciences 23 (4), 2315, 2022 | 2 | 2022 |
A rationally designed orthogonal synthetase for genetically encoded fluorescent amino acids X Steinberg, J Galpin, G Nasir, RV Sepúlveda, EL de Guevara, ... Heliyon 6 (10), 2020 | 2 | 2020 |
A rationally designed aminoacyl-trna synthetase for genetically encoded fluorescent amino acids X Steinberg, J Galpin, G Nasir, J Sepulveda-Ugarte, RV Sepúlveda, ... bioRxiv, 065227, 2016 | 2 | 2016 |
Properties of Two Novel Esterases Identified from Culture Supernatant of Penicillium purpurogenum Grown on Sugar Beet Pulp G Oleas, E Callegari, R Sepulveda, J Eyzaguirre Insights in enzyme research 1 (1), 2016 | 2 | 2016 |
Insights into Early Steps of Decanoic Acid Self-Assemblies under Prebiotic Temperatures Using Molecular Dynamics Simulations RV Sepulveda, C Sbarbaro, MC Opazo, Y Duarte, F González-Nilo, ... Membranes 13 (5), 469, 2023 | 1 | 2023 |
A method for characterizing the thermal stability and antimicrobial binding to Lipopolysaccharides of Gram-negative isogenic mutant strains B Navarro, M Alarcón, M Osees, F Gómez-Alvear, RV Sepúlveda, ... MethodsX 8, 101474, 2021 | 1 | 2021 |