Rare epidermal growth factor receptor (EGFR) mutations in non-small cell lung cancer PT Harrison, S Vyse, PH Huang Seminars in cancer biology 61, 167-179, 2020 | 447 | 2020 |
Targeting EGFR exon 20 insertion mutations in non-small cell lung cancer S Vyse, PH Huang Signal transduction and targeted therapy 4 (1), 5, 2019 | 328 | 2019 |
UBE2L3 polymorphism amplifies NF-κB activation and promotes plasma cell development, linking linear ubiquitination to multiple autoimmune diseases MJ Lewis, S Vyse, AM Shields, S Boeltz, PA Gordon, TD Spector, ... The American Journal of Human Genetics 96 (2), 221-234, 2015 | 98 | 2015 |
Primary cilia mediate diverse kinase inhibitor resistance mechanisms in cancer AD Jenks, S Vyse, JP Wong, E Kostaras, D Keller, T Burgoyne, ... Cell reports 23 (10), 3042-3055, 2018 | 90 | 2018 |
Dual targeting of PDGFRα and FGFR1 displays synergistic efficacy in malignant rhabdoid tumors JP Wong, JR Todd, MA Finetti, F McCarthy, M Broncel, S Vyse, ... Cell reports 17 (5), 1265-1275, 2016 | 52 | 2016 |
De novo mutations implicate novel genes in systemic lupus erythematosus V Pullabhatla, AL Roberts, MJ Lewis, D Mauro, DL Morris, CA Odhams, ... Human molecular genetics 27 (3), 421-429, 2018 | 45 | 2018 |
Three‐dimensional modelling identifies novel genetic dependencies associated with breast cancer progression in the isogenic MCF10 model SL Maguire, B Peck, PT Wai, J Campbell, H Barker, A Gulati, F Daley, ... The Journal of Pathology 240 (3), 315-328, 2016 | 42 | 2016 |
Exploiting receptor tyrosine kinase co-activation for cancer therapy AC Tan, S Vyse, PH Huang Drug discovery today 22 (1), 72-84, 2017 | 40 | 2017 |
Systematic analysis of tumour cell-extracellular matrix adhesion identifies independent prognostic factors in breast cancer JR Todd, KA Ryall, S Vyse, JP Wong, RC Natrajan, Y Yuan, AC Tan, ... Oncotarget 7 (39), 62939, 2016 | 38 | 2016 |
Improved monitoring of clinical response in Systemic Lupus Erythematosus by longitudinal trend in soluble vascular cell adhesion molecule-1 MJ Lewis, S Vyse, AM Shields, L Zou, M Khamashta, PA Gordon, ... Arthritis research & therapy 18, 1-11, 2016 | 37 | 2016 |
Quantitative phosphoproteomic analysis of acquired cancer drug resistance to pazopanib and dasatinib S Vyse, F McCarthy, M Broncel, A Paul, JP Wong, A Bhamra, PH Huang Journal of proteomics 170, 130-140, 2018 | 32 | 2018 |
Amivantamab for the treatment of EGFR exon 20 insertion mutant non-small cell lung cancer S Vyse, PH Huang Expert Review of Anticancer Therapy 22 (1), 3-16, 2022 | 24 | 2022 |
Advances in mass spectrometry based strategies to study receptor tyrosine kinases S Vyse, H Desmond, PH Huang IUCrJ 4 (2), 119-130, 2017 | 21 | 2017 |
Next-generation sequencing for the management of sarcomas with no known driver mutations S Vyse, K Thway, PH Huang, RL Jones Current Opinion in Oncology 33 (4), 315-322, 2021 | 20 | 2021 |
Tackling drug resistance in EGFR exon 20 insertion mutant lung cancer L Pacini, AD Jenks, S Vyse, CP Wilding, A Arthur, PH Huang Pharmacogenomics and personalized medicine, 301-317, 2021 | 20 | 2021 |
Exploiting synthetic lethality and network biology to overcome EGFR inhibitor resistance in lung cancer S Vyse, A Howitt, PH Huang Journal of molecular biology 429 (12), 1767-1786, 2017 | 19 | 2017 |
Effect of UBE2L3 genotype on regulation of the linear ubiquitin chain assembly complex in systemic lupus erythematosus M Lewis, S Vyse, A Shields, S Boeltz, P Gordon, T Spector, P Lehner, ... The Lancet 385, S9, 2015 | 17 | 2015 |
Targeting EGFR exon 20 insertions in non-small cell lung cancer by exploiting a dependency on parallel SRC signalling S Vyse, N Chen, J Oddy, P Harrison, A Le, A Estrada-Bernal, M Hermsen, ... Annals of Oncology 30, vii3, 2019 | | 2019 |
De novo mutations implicate novel genes with burden of rare variants in Systemic Lupus Erythematosus V Pullabhatla, AL Roberts, MJ Lewis, D Mauro, DL Morris, CA Odhams, ... bioRxiv, 139238, 2017 | | 2017 |
OP0232 C1qtnf4 Mutation Identified by Exome Sequencing Is Associated with Systemic Lupus Erythematosus and Dysregulation of Tnf-Induced Apoptosis D Mauro, MJ Lewis, V Pullabhatla, S Vyse, M Simpson, ... Annals of the Rheumatic Diseases 75 (Suppl 2), 145-146, 2016 | | 2016 |