Complex oscillatory waves emerging from cortical organoids model early human brain network development CA Trujillo, R Gao, PD Negraes, J Gu, J Buchanan, S Preissl, A Wang, ... Cell stem cell 25 (4), 558-569. e7, 2019 | 649 | 2019 |
Modeling of TREX1-dependent autoimmune disease using human stem cells highlights L1 accumulation as a source of neuroinflammation CA Thomas, L Tejwani, CA Trujillo, PD Negraes, RH Herai, P Mesci, ... Cell stem cell 21 (3), 319-331. e8, 2017 | 291 | 2017 |
Zika virus targets glioblastoma stem cells through a SOX2-integrin αvβ5 axis Z Zhu, P Mesci, JA Bernatchez, RC Gimple, X Wang, ST Schafer, ... Cell stem cell 26 (2), 187-204. e10, 2020 | 144 | 2020 |
Reintroduction of the archaic variant of NOVA1 in cortical organoids alters neurodevelopment CA Trujillo, ES Rice, NK Schaefer, IA Chaim, EC Wheeler, AA Madrigal, ... Science 371 (6530), eaax2537, 2021 | 128 | 2021 |
Cortical organoids model early brain development disrupted by 16p11. 2 copy number variants in autism J Urresti, P Zhang, P Moran-Losada, NK Yu, PD Negraes, CA Trujillo, ... Molecular psychiatry 26 (12), 7560-7580, 2021 | 81 | 2021 |
DNA methylation patterns in bladder cancer and washing cell sediments: a perspective for tumor recurrence detection PD Negraes, FP Favaro, JLV Camargo, MLCS Oliveira, J Goldberg, ... BMC cancer 8, 1-12, 2008 | 70 | 2008 |
Chemical genetic identification of CDKL 5 substrates reveals its role in neuronal microtubule dynamics LL Baltussen, PD Negraes, M Silvestre, S Claxton, M Moeskops, ... The EMBO journal 37 (24), e99763, 2018 | 69 | 2018 |
Pharmacological reversal of synaptic and network pathology in human MECP2‐KO neurons and cortical organoids CA Trujillo, JW Adams, PD Negraes, C Carromeu, L Tejwani, A Acab, ... EMBO Molecular Medicine 13 (1), e12523, 2021 | 64 | 2021 |
Kinin-B2 receptor activity determines the differentiation fate of neural stem cells CA Trujillo, PD Negraes, TT Schwindt, C Lameu, C Carromeu, AR Muotri, ... Journal of Biological Chemistry 287 (53), 44046-44061, 2012 | 57 | 2012 |
Altered network and rescue of human neurons derived from individuals with early-onset genetic epilepsy PD Negraes, CA Trujillo, NK Yu, W Wu, H Yao, N Liang, JD Lautz, E Kwok, ... Molecular psychiatry 26 (11), 7047-7068, 2021 | 49 | 2021 |
Natural intracellular peptides can modulate the interactions of mouse brain proteins and thimet oligopeptidase with 14‐3‐3ε and calmodulin LC Russo, AF Asega, LM Castro, PD Negraes, L Cruz, FC Gozzo, H Ulrich, ... Proteomics 12 (17), 2641-2655, 2012 | 47 | 2012 |
Interactions between the NO-citrulline cycle and brain-derived neurotrophic factor in differentiation of neural stem cells C Lameu, CA Trujillo, TT Schwindt, PD Negraes, MM Pillat, KLP Morais, ... Journal of Biological Chemistry 287 (35), 29690-29701, 2012 | 45 | 2012 |
Directed differentiation of neural progenitors into neurons is accompanied by altered expression of P2X purinergic receptors TT Schwindt, CA Trujillo, PD Negraes, C Lameu, H Ulrich Journal of Molecular Neuroscience 44, 141-146, 2011 | 42 | 2011 |
Retinoic acid-treated pluripotent stem cells undergoing neurogenesis present increased aneuploidy and micronuclei formation RC Sartore, PB Campos, CA Trujillo, BL Ramalho, PD Negraes, ... PloS one 6 (6), e20667, 2011 | 38 | 2011 |
Regulation of neurogenesis and gliogenesis of retinoic acid-induced P19 embryonal carcinoma cells by P2X2 and P2X7 receptors studied by RNA interference KK Yuahasi, MA Demasi, ASK Tamajusuku, G Lenz, MC Sogayar, ... International Journal of Developmental Neuroscience 30 (2), 91-97, 2012 | 35 | 2012 |
Methadone interrupts neural growth and function in human cortical organoids H Yao, W Wu, I Cerf, HW Zhao, J Wang, PD Negraes, AR Muotri, ... Stem Cell Research 49, 102065, 2020 | 32 | 2020 |
Roles of kinins in the nervous system PD Negraes, CA Trujillo, MM Pillat, YD Teng, H Ulrich Cell Transplantation 24 (4), 613-623, 2015 | 32 | 2015 |
Bradykinin promotes neuron-generating division of neural progenitor cells through ERK activation MM Pillat, C Lameu, CA Trujillo, T Glaser, AR Cappellari, PD Negraes, ... Journal of cell science 129 (18), 3437-3448, 2016 | 31 | 2016 |
The snake venom peptide Bj‐PRO‐7a is a M1 muscarinic acetylcholine receptor agonist PD Negraes, C Lameu, MAF Hayashi, RL Melo, ACM Camargo, H Ulrich Cytometry part A 79 (1), 77-83, 2011 | 29 | 2011 |
Evidence of nuclei-encoded spliceosome mediating splicing of mitochondrial RNA RH Herai, PD Negraes, AR Muotri Human molecular genetics 26 (13), 2472-2479, 2017 | 25 | 2017 |