| Targeted insertional mutagenesis libraries for deep domain insertion profiling W Coyote-Maestas, D Nedrud, S Okorafor, Y He, D Schmidt Nucleic acids research 48 (2), e11-e11, 2020 | 38 | 2020 |
| Determinants of trafficking, conduction, and disease within a K+ channel revealed through multiparametric deep mutational scanning W Coyote-Maestas, D Nedrud, Y He, D Schmidt Elife 11, e76903, 2022 | 35 | 2022 |
| DIMPLE: deep insertion, deletion, and missense mutation libraries for exploring protein variation in evolution, disease, and biology CB Macdonald, D Nedrud, PR Grimes, D Trinidad, JS Fraser, ... Genome biology 24 (1), 36, 2023 | 27 | 2023 |
| Uncovering divergent evolution of α/β-hydrolases: a surprising residue substitution needed to convert Hevea brasiliensis hydroxynitrile lyase into an esterase DM Nedrud, H Lin, G Lopez, SK Padhi, GA Legatt, RJ Kazlauskas Chemical science 5 (11), 4265-4277, 2014 | 27 | 2014 |
| Probing ion channel functional architecture and domain recombination compatibility by massively parallel domain insertion profiling W Coyote-Maestas, D Nedrud, A Suma, Y He, KA Matreyek, DM Fowler, ... Nature communications 12 (1), 7114, 2021 | 23 | 2021 |
| Increasing the Reaction Rate of Hydroxynitrile Lyase from Hevea brasiliensis toward Mandelonitrile by Copying Active Site Residues from an Esterase that Accepts … J Von Langermann, DM Nedrud, RJ Kazlauskas ChemBioChem 15 (13), 1931-1938, 2014 | 18 | 2014 |
| A large‐scale survey of pairwise epistasis reveals a mechanism for evolutionary expansion and specialization of PDZ domains D Nedrud, W Coyote‐Maestas, D Schmidt Proteins: Structure, Function, and Bioinformatics 89 (8), 899-914, 2021 | 17 | 2021 |
| Multiparametric domain insertional profiling of adeno-associated virus VP1 MD Hoffmann, AC Zdechlik, Y He, D Nedrud, G Aslanidi, W Gordon, ... Molecular Therapy-Methods & Clinical Development 31, 2023 | 6 | 2023 |
| Deep insertion, deletion, and missense mutation libraries for exploring protein variation in evolution, disease, and biology CB Macdonald, D Nedrud, PR Grimes, D Trinidad, JS Fraser, ... BioRxiv, 2022.07. 26.501589, 2022 | 4 | 2022 |
| DIMPLE library generation and assembly protocol C Macdonald, D Nedrud, PR Grimes, D Trinidad, C Shin, J Fraser, ... | 1 | 2023 |
| The biophysical basis of protein domain compatibility in ion channels W Coyote-Maestas, D Nedrud, A Suma, Y He, KA Matreyek, DM Fowler, ... bioRxiv, 2020.12. 09.418442, 2020 | 1 | 2020 |
| A survey of pairwise epistasis supports an outside-in hierarchy of clade-specifying and function-defining residues in PSD95 PDZ3 D Nedrud, W Coyote-Maestas, D Schmidt bioRxiv, 2020.06. 26.174375, 2020 | 1 | 2020 |
| Deep insertional mutagenesis and multiplex assessment of phenotype reveals biophysical mechanisms of protein domain compatibility D Schmidt, W Coyote-Maestas, D Nedrud, M Hoffmann Biophysical Journal 121 (3), 156a, 2022 | | 2022 |
| Deconvoluting receptor trafficking, regulation, and function using massively parallel assays D Nedrud, Y He, D Schmidt, J Fraser, W Coyote-Maestas Biophysical Journal 121 (3), 2a, 2022 | | 2022 |
| The Biophysical basis of protein domain compatibility D Schmidt, W Coyote-Maestas, D Nedrud, A Suma, Y He, KA Matreyek, ... PROTEIN SCIENCE 30, 73-74, 2021 | | 2021 |
| Comprehensive Domain Insertion Profiling to Study Inward Rectifier K+ Channel Folding Robustness W Coyote-Maestas, D Nedrud, Y He, D Schmidt Biophysical Journal 120 (3), 338a-339a, 2021 | | 2021 |
| Programmed mutagenesis and high-throughput methods to study protein recombination and epistasis D Nedrud University of Minnesota, 2021 | | 2021 |
| Deep Domain Insertion Profiling is a Window into Inward Rectifier K+ Channel Dynamics and Gating W Coyote-Maestas, A Suma, D Nedrud, V Carnevale, D Schmidt Biophysical Journal 118 (3), 320a, 2020 | | 2020 |
| PROFILING LATENT AND ENGINEERABLE ALLOSTERY IN ION CHANNELS THROUGH SYSTEMATIC DOMAIN INSERTION D Schmidt, W Coyote-Maestas, D Nedrud, Y He, C Myers PROTEIN SCIENCE 28, 95-95, 2019 | | 2019 |
| Efficient mesoscale phenotypic screening in cultured primary neuron culture D Nedrud, Y He, D Schmidt bioRxiv, 562298, 2019 | | 2019 |
