PACS‐2 controls endoplasmic reticulum–mitochondria communication and Bid‐mediated apoptosis T Simmen, JE Aslan, AD Blagoveshchenskaya, L Thomas, L Wan, ... The EMBO journal 24 (4), 717-729, 2005 | 614 | 2005 |
Probing cellular protein complexes using single-molecule pull-down A Jain, R Liu, B Ramani, E Arauz, Y Ishitsuka, K Ragunathan, J Park, ... Nature 473 (7348), 484-488, 2011 | 458 | 2011 |
Sequential binding of agonists to the β2 adrenoceptor: kinetic evidence for intermediate conformational states G Swaminath, Y Xiang, TW Lee, J Steenhuis, C Parnot, BK Kobilka Journal of Biological Chemistry 279 (1), 686-691, 2004 | 447 | 2004 |
β2-Adrenoreceptor is a regulator of the α-synuclein gene driving risk of Parkinson’s disease S Mittal, K Bjørnevik, DS Im, A Flierl, X Dong, JJ Locascio, KM Abo, ... Science 357 (6354), 891-898, 2017 | 441 | 2017 |
PACS-1 defines a novel gene family of cytosolic sorting proteins required for trans-Golgi network localization L Wan, SS Molloy, L Thomas, G Liu, Y Xiang, SL Rybak, G Thomas Cell 94 (2), 205-216, 1998 | 441 | 1998 |
α1-Antitrypsin Portland, a bioengineered serpin highly selective for furin: Application as an antipathogenic agent F Jean, K Stella, L Thomas, G Liu, Y Xiang, AJ Reason, G Thomas Proceedings of the National Academy of Sciences 95 (13), 7293-7298, 1998 | 346 | 1998 |
Receptor number and caveolar co-localization determine receptor coupling efficiency to adenylyl cyclase RS Ostrom, C Gregorian, RM Drenan, Y Xiang, JW Regan, PA Insel Journal of Biological Chemistry 276 (45), 42063-42069, 2001 | 332 | 2001 |
Caveolar localization dictates physiologic signaling of β2-adrenoceptors in neonatal cardiac myocytes Y Xiang, VO Rybin, SF Steinberg, B Kobilka Journal of Biological Chemistry 277 (37), 34280-34286, 2002 | 311 | 2002 |
Myocyte adrenoceptor signaling pathways Y Xiang, BK Kobilka Science 300 (5625), 1530-1532, 2003 | 299 | 2003 |
β-adrenergic receptor subtype-specific signaling in cardiac myocytes from β1 and β2 adrenoceptor knockout mice E Devic, Y Xiang, D Gould, B Kobilka Molecular pharmacology 60 (3), 577-583, 2001 | 262 | 2001 |
MiR-152 and miR-185 co-contribute to ovarian cancer cells cisplatin sensitivity by targeting DNMT1 directly: a novel epigenetic therapy independent of decitabine Y Xiang, N Ma, D Wang, Y Zhang, J Zhou, G Wu, R Zhao, H Huang, ... Oncogene 33 (3), 378-386, 2014 | 248 | 2014 |
PACS-1 binding to adaptors is required for acidic cluster motif-mediated protein traffic CM Crump, Y Xiang, L Thomas, F Gu, C Austin, SA Tooze, G Thomas The EMBO journal 20 (9), 2191-2201, 2001 | 246 | 2001 |
Oleic acid stimulates complete oxidation of fatty acids through protein kinase A-dependent activation of SIRT1-PGC1α complex JH Lim, Z Gerhart-Hines, JE Dominy, Y Lee, S Kim, M Tabata, YK Xiang, ... Journal of Biological Chemistry 288 (10), 7117-7126, 2013 | 241 | 2013 |
Single-molecule pull-down for studying protein interactions A Jain, R Liu, YK Xiang, T Ha Nature protocols 7 (3), 445-452, 2012 | 234 | 2012 |
Epigenetic regulation of phosphodiesterases 2A and 3A underlies compromised β-adrenergic signaling in an iPSC model of dilated cardiomyopathy H Wu, J Lee, LG Vincent, Q Wang, M Gu, F Lan, JM Churko, KI Sallam, ... Cell stem cell 17 (1), 89-100, 2015 | 195 | 2015 |
Cardiotoxic and cardioprotective features of chronic β-adrenergic signaling X Zhang, C Szeto, E Gao, M Tang, J Jin, Q Fu, C Makarewich, X Ai, Y Li, ... Circulation research 112 (3), 498-509, 2013 | 192 | 2013 |
Mechanochemical delivery and dynamic tracking of fluorescent quantum dots in the cytoplasm and nucleus of living cells K Yum, S Na, Y Xiang, N Wang, MF Yu Nano letters 9 (5), 2193-2198, 2009 | 159 | 2009 |
Phosphodiesterase 4D is required for β2 adrenoceptor subtype-specific signaling in cardiac myocytes Y Xiang, F Naro, M Zoudilova, SLC Jin, M Conti, B Kobilka Proceedings of the National Academy of Sciences 102 (3), 909-914, 2005 | 148 | 2005 |
Empagliflozin ameliorates obesity-related cardiac dysfunction by regulating Sestrin2-mediated AMPK-mTOR signaling and redox homeostasis in high-fat diet–induced obese mice X Sun, F Han, Q Lu, X Li, D Ren, J Zhang, Y Han, YK Xiang, J Li Diabetes 69 (6), 1292-1305, 2020 | 142 | 2020 |
The PDZ binding motif of the β1 adrenergic receptor modulates receptor trafficking and signaling in cardiac myocytes Y Xiang, E Devic, B Kobilka Journal of Biological Chemistry 277 (37), 33783-33790, 2002 | 134 | 2002 |