The arginine methyltransferase PRMT7 promotes extravasation of monocytes resulting in tissue injury in COPD G Günes Günsel, TM Conlon, A Jeridi, R Kim, Z Ertüz, NJ Lang, M Ansari, ... Nature communications 13 (1), 1303, 2022 | 61 | 2022 |
IL‐37 regulates allergic inflammation by counterbalancing pro‐inflammatory IL‐1 and IL‐33 A Schröder, LP Lunding, UM Zissler, C Vock, S Webering, JC Ehlers, ... Allergy 77 (3), 856-869, 2022 | 39 | 2022 |
Single-cell RNA sequencing reveals ex vivo signatures of SARS-CoV-2-reactive T cells through ‘reverse phenotyping’ DS Fischer, M Ansari, KI Wagner, S Jarosch, Y Huang, CH Mayr, M Strunz, ... Nature communications 12 (1), 4515, 2021 | 33 | 2021 |
Sfrp1 inhibits lung fibroblast invasion during transition to injury-induced myofibroblasts CH Mayr, A Sengupta, S Asgharpour, M Ansari, JC Pestoni, P Ogar, ... European Respiratory Journal 63 (2), 2024 | 28 | 2024 |
Ex vivo tissue perturbations coupled to single-cell RNA-seq reveal multilineage cell circuit dynamics in human lung fibrogenesis NJ Lang, J Gote-Schniering, D Porras-Gonzalez, L Yang, LJ De Sadeleer, ... Science translational medicine 15 (725), eadh0908, 2023 | 25 | 2023 |
Ferroptosis, induced by macrophages drives COPD pathogenesis A Jeridi, GG Günsel, M Novikava, S Doll, NJ Lang, SE Verleden, ... ERJ Open Research 8 (suppl 8), 2022 | 4 | 2022 |
An open-source framework for end-to-end analysis of electronic health record data L Heumos, P Ehmele, T Treis, J Upmeier zu Belzen, E Roellin, L May, ... Nature Medicine, 1-12, 2024 | 1 | 2024 |
Spatiotemporal analysis of inflammaging and senescence programs in lung fibrosis using time-resolved single-cell transcriptomics and multiplexed immunofluorescence J Gote-Schniering, M Lehmann, M Ansari, K Wiedemann, ... European Respiratory Journal 62 (suppl 67), 2023 | 1 | 2023 |
Ex vivo modelling of human lung fibrogenesis and drug mode of action screens using single-cell RNA-seq in precision-cut lung slices N Lang, M Ansari, D Porras-Gonzalez, A Agami, BH Kashani, S Zhou, ... ERJ Open Research 8 (suppl 8), 2022 | 1 | 2022 |
Identification of Antifibrotic N23Ps' Mode of Action (MoA) by Advanced 3D Human Fibrosis Models DL Porras-Gonzalez, NJ Lang, K Merchant, X Wei, A Agami, HL Ma, ... A71. CUTTING EDGE TECHNOLOGIES FOR LUNG DISCOVERY, A2536-A2536, 2024 | | 2024 |
Emerging Volumetric Imaging Coupled to Multi-omics: Probing Cellular Dynamics and Tissue Niches of Human Lungs in Health and Disease L Yang, A Agami, L De Sadeleer, Y Chen, TH Phuong Vo, J Schniering, ... A71. CUTTING EDGE TECHNOLOGIES FOR LUNG DISCOVERY, A2551-A2551, 2024 | | 2024 |
Late Breaking Abstract-Evolution of epithelial-mesenchymal cell circuits in the progression of pulmonary fibrosis L De Sadeleer, Y Chen, C Jentzsch, Z Wang, N Qazi, N Lang, P Albanese, ... European Respiratory Journal 62 (suppl 67), 2023 | | 2023 |
Resolving Age-dependent Cellular Senescence Programs in Lung Fibrosis Using Longitudinal Single Cell Transcriptomics M Lehmann, J Schniering, M Ansari, MC Melo-Narváez, C Steinchen, ... A16. INTERROGATING GENOMIC, TRANSCRIPTIONAL, AND EPIGENETIC MECHANISMS IN …, 2023 | | 2023 |
COPD pathogenesis is dependent on ferroptotic death of AT2 cells driven by pro-inflammatory Macrophages A Jeridi, TM Conlon, GG Günsel, M Novikova, S Doll, NJ Lang, ... European Respiratory Journal 60 (suppl 66), 2022 | | 2022 |
Monocyte migration epigenetically regulated by PRMT7 driving COPD pathogenesis T Conlon, A Jeridi, GG Günsel, NJ Lang, M Ansari, HP Van Eeckhoutte, ... European Respiratory Journal 60 (suppl 66), 2022 | | 2022 |
Resolving the Cellular Programs of Lung Aging in Pulmonary Fibrosis at Single-Cell Resolution J Schniering, M Lehmann, M Ansari, MC Melo Narvaez, CH Mayr, Y Chen, ... C109. PULMONARY FIBROSIS: MOVING FORWARD WITH GENETICS AND SEQUENCING, A5791 …, 2022 | | 2022 |
N23Ps as a Novel Highly Potent Antifibrotic Therapeutic Compound Class and Discovery of Its Mode of Action in a Human Ex Vivo Fibrosis Model X Wei, M Gerckens, D Porras-Gonzalez, NJ Lang, C Mayr, B Ballester, ... C17. NOVEL THERAPEUTICS AND BIOMARKERS FOR IDIOPATHIC PULMONARY FIBROSIS …, 2022 | | 2022 |
Macrophage Induced Ferroptotic Cell Death of Epithelial Cells Drives COPD Pathogenesis A Jeridi, G Günes Günsel, M Novikova, S Doll, NJ Lang, M Ansari, ... A17. COPD: SINGLE CELL RNA SEQUENCING, EPIGENETICS, MODELS, AND MACROPHAGES …, 2022 | | 2022 |
PRMT7 Epigenetically Regulates Monocyte Migration and COPD Pathogenesis TM Conlon, A Jeridi, G Günes Günsel, NJ Lang, G Burgstaller, ... A17. COPD: SINGLE CELL RNA SEQUENCING, EPIGENETICS, MODELS, AND MACROPHAGES …, 2022 | | 2022 |
Resolving aging-related cellular phenotypes in pulmonary fibrosis by longitudinal single-cell transcriptomics J Schniering, M Lehmann, M Ansari, MCM Narvaez, CH Mayr, Y Chen, ... ERJ Open Research 8 (suppl 8), 2022 | | 2022 |