Molecular basis of human hypertension: role of angiotensinogen X Jeunemaitre, F Soubrier, YV Kotelevtsev, RP Lifton, CS Williams, ... Cell 71 (1), 169-180, 1992 | 2589 | 1992 |
11β-hydroxysteroid dehydrogenase type 1 knockout mice show attenuated glucocorticoid-inducible responses and resist hyperglycemia on obesity or stress Y Kotelevtsev, MC Holmes, A Burchell, PM Houston, D Schmoll, ... Proceedings of the National Academy of Sciences 94 (26), 14924-14929, 1997 | 1150 | 1997 |
Cholangiocytes act as facultative liver stem cells during impaired hepatocyte regeneration A Raven, WY Lu, TY Man, S Ferreira-Gonzalez, E O’Duibhir, BJ Dwyer, ... Nature 547 (7663), 350-354, 2017 | 492 | 2017 |
The ontogeny of 11 beta-hydroxysteroid dehydrogenase type 2 and mineralocorticoid receptor gene expression reveal intricate control of glucocorticoid action in development RW Brown, R Diaz, AC Robson, YV Kotelevtsev, JJ Mullins, MH Kaufman, ... Endocrinology 137 (2), 794-797, 1996 | 368 | 1996 |
Hypertension in mice lacking 11β-hydroxysteroid dehydrogenase type 2 Y Kotelevtsev, RW Brown, S Fleming, C Kenyon, CRW Edwards, JR Seckl, ... The Journal of clinical investigation 103 (5), 683-689, 1999 | 327 | 1999 |
Intracellular regeneration of glucocorticoids by 11β-hydroxysteroid dehydrogenase (11β-HSD)-1 plays a key role in regulation of the hypothalamic-pituitary-adrenal axis … HJ Harris, Y Kotelevtsev, JJ Mullins, JR Seckl, MC Holmes Endocrinology 142 (1), 114-120, 2001 | 278 | 2001 |
Collecting duct-specific knockout of the endothelin B receptor causes hypertension and sodium retention Y Ge, A Bagnall, PK Stricklett, K Strait, DJ Webb, Y Kotelevtsev, DE Kohan American Journal of Physiology-Renal Physiology 291 (6), F1274-F1280, 2006 | 256 | 2006 |
Lack of tissue glucocorticoid reactivation in 11β-hydroxysteroid dehydrogenase type 1 knockout mice ameliorates age-related learning impairments JLW Yau, J Noble, CJ Kenyon, C Hibberd, Y Kotelevtsev, JJ Mullins, ... Proceedings of the National Academy of Sciences 98 (8), 4716-4721, 2001 | 255 | 2001 |
Cloning and production of antisera to human placental 11 β-hydroxysteroid dehydrogenase type 2 RW BROWN, KE CHAPMAN, Y KOTELEVTSEV, JLW YAU, RS LINDSAY, ... Biochemical Journal 313 (3), 1007-1017, 1996 | 217 | 1996 |
Angiotensinogen: a candidate gene involved in preeclampsia? R Arngrímsson, S Purandare, M Connor, JJ Walker, S Björnsson, ... Nature Genetics 4 (2), 114-115, 1993 | 204 | 1993 |
Adenoviral gene delivery of elafin and secretory leukocyte protease inhibitor attenuates NF-κB-dependent inflammatory responses of human endothelial cells and macrophages to … PA Henriksen, M Hitt, Z Xing, J Wang, C Haslett, RA Riemersma, ... The Journal of Immunology 172 (7), 4535-4544, 2004 | 189 | 2004 |
Controlled hypertension, a transgenic toggle switch reveals differential mechanisms underlying vascular disease S Kantachuvesiri, S Fleming, J Peters, B Peters, G Brooker, AG Lammie, ... Journal of Biological Chemistry 276 (39), 36727-36733, 2001 | 183 | 2001 |
Lipid nanoparticles for targeted siRNA delivery–going from bench to bedside TS Zatsepin, YV Kotelevtsev, V Koteliansky International journal of nanomedicine, 3077-3086, 2016 | 179 | 2016 |
Human Mineralocorticoid Receptor Genomic Structure and Identification of Expressed Isoforms (∗) MC Zennaro, MC Keightley, Y Kotelevtsev, GS Conway, F Soubrier, ... Journal of Biological Chemistry 270 (36), 21016-21020, 1995 | 176 | 1995 |
Atherosclerosis and Alzheimer-diseases with a common cause? Inflammation, oxysterols, vasculature R Lathe, A Sapronova, Y Kotelevtsev BMC geriatrics 14, 1-30, 2014 | 163 | 2014 |
Genetic determinants of diastolic and pulse pressure map to different loci in Lyon hypertensive rats C Dubay, M Vincent, NJ Samani, P Hilbert, MA Kaiser, JP Beressi, ... Nature genetics 3 (4), 354-357, 1993 | 143 | 1993 |
Deletion of endothelial cell endothelin B receptors does not affect blood pressure or sensitivity to salt AJ Bagnall, NF Kelland, F Gulliver-Sloan, AP Davenport, GA Gray, ... Hypertension 48 (2), 286-293, 2006 | 131 | 2006 |
Direct action of endothelin-1 on podocytes promotes diabetic glomerulosclerosis O Lenoir, M Milon, A Virsolvy, C Hénique, A Schmitt, JM Massé, ... Journal of the American Society of Nephrology 25 (5), 1050-1062, 2014 | 116 | 2014 |
Endothelial cell dysfunction in mice after transgenic knockout of type 2, but not type 1, 11β-hydroxysteroid dehydrogenase PWF Hadoke, C Christy, YV Kotelevtsev, BC Williams, CJ Kenyon, ... Circulation 104 (23), 2832-2837, 2001 | 111 | 2001 |
Combined knockout of collecting duct endothelin A and B receptors causes hypertension and sodium retention Y Ge, A Bagnall, PK Stricklett, D Webb, Y Kotelevtsev, DE Kohan American Journal of Physiology-Renal Physiology 295 (6), F1635-F1640, 2008 | 105 | 2008 |