Downregulation of delayed rectifier K+ currents in dogs with chronic complete atrioventricular block and acquired torsades de pointes PGA Volders, KR Sipido, MA Vos, RL Spätjens, JDM Leunissen, ... Circulation 100 (24), 2455-2461, 1999 | 311 | 1999 |
Probing the contribution of IKs to canine ventricular repolarization: key role for β-adrenergic receptor stimulation PGA Volders, M Stengl, JM van Opstal, U Gerlach, RL Spätjens, ... Circulation 107 (21), 2753-2760, 2003 | 295 | 2003 |
Repolarizing K+ currents ITO1 and IKs are larger in right than left canine ventricular midmyocardium PGA Volders, KR Sipido, E Carmeliet, RL Spätjens, HJJ Wellens, MA Vos Circulation 99 (2), 206-210, 1999 | 290 | 1999 |
Accumulation of slowly activating delayed rectifier potassium current (IKs) in canine ventricular myocytes M Stengl, PGA Volders, MB Thomsen, RL Spätjens, KR Sipido, MA Vos The Journal of Physiology 551 (3), 777-786, 2003 | 121 | 2003 |
Dominant-Negative Control of cAMP-Dependent IKs Upregulation in Human Long-QT Syndrome Type 1 J Heijman, RL Spätjens, SRM Seyen, V Lentink, HJH Kuijpers, IR Boulet, ... Circulation Research 110 (2), 211-219, 2012 | 78 | 2012 |
Dominant-Negative Control of cAMP-Dependent IKs Upregulation in Human Long-QT Syndrome Type 1 J Heijman, RL Spätjens, SR Seyen, V Lentink, HJ Kuijpers, IR Boulet, ... Circulation 124 (Suppl 21), A10189-A10189, 2011 | 78 | 2011 |
Electrophysiological safety of sertindole in dogs with normal and remodeled hearts MB Thomsen, PGA Volders, M Stengl, RL Spätjens, JDM Beekman, ... Journal of Pharmacology and Experimental Therapeutics 307 (2), 776-784, 2003 | 71 | 2003 |
Temporal patterns of electrical remodeling in canine ventricular hypertrophy: Focus on IKs downregulation and blunted β-adrenergic activation M Stengl, C Ramakers, DW Donker, A Nabar, AV Rybin, RL Spätjens, ... Cardiovascular research 72 (1), 90-100, 2006 | 63 | 2006 |
Interventricular Differences in β‐Adrenergic Responses in the Canine Heart: Role of Phosphodiesterases CE Molina, DM Johnson, H Mehel, RL Spätjens, D Mika, V Algalarrondo, ... Journal of the American Heart Association 3 (3), e000858, 2014 | 42 | 2014 |
End–diastolic myofiber stress and ejection strain increase with ventricular volume overload: Serial in–vivo analyses in dogs with complete atrioventricular block DW Donker, PGA Volders, T Arts, BCAM Bekkers, L Hofstra, R Spätjens, ... Basic research in cardiology 100, 372-382, 2005 | 35 | 2005 |
Impact of acute and enduring volume overload on mechanotransduction and cytoskeletal integrity of canine left ventricular myocardium DW Donker, JG Maessen, F Verheyen, FC Ramaekers, RL Spätjens, ... American Journal of Physiology-Heart and Circulatory Physiology 292 (5 …, 2007 | 32 | 2007 |
Mutation location and IKs regulation in the arrhythmic risk of long QT syndrome type 1: the importance of the KCNQ1 S6 region P Schwartz, C Moreno, MC Kotta, M Pedrazzini, L Crotti, F Dagradi, ... European Heart Journal, 2021 | 27 | 2021 |
Molecular and electrical characterization of the canine cardiac ventricular septum C Ramakers, M Stengl, RL Spätjens, AFM Moorman, MA Vos Journal of molecular and cellular cardiology 38 (1), 153-161, 2005 | 25 | 2005 |
Long-QT mutation p. K557E-Kv7. 1: dominant-negative suppression of IKs, but preserved cAMP-dependent up-regulation RL Spätjens, M Bébarová, SRM Seyen, V Lentink, RJ Jongbloed, ... Cardiovascular research 104 (1), 216-225, 2014 | 11 | 2014 |
Repolarization instability and arrhythmia by IKr block in single human-induced pluripotent stem cell-derived cardiomyocytes and 2D monolayers C Altrocchi, T de Korte, J Bernardi, RL Spätjens, SR Braam, J Heijman, ... EP Europace 22 (9), 1431-1441, 2020 | 10 | 2020 |
Measurement of Action Potential Generation in Isolated Canine Left Ventricular Midmyocardial Myocytes DM Johnson, L Hussein, RL Spätjens, JP Valentin, PGA Volders, ... Current Protocols in Pharmacology, 2011 | 5 | 2011 |
Electrophysiological and proarrhythmic parameters in transmural canine left-ventricular needle biopsies SC Verduyn, JGM Jungschleger, M Stengl, RL Spätjens, JDM Beekman, ... Pflügers Archiv 449, 115-122, 2004 | 5 | 2004 |
Serial left-ventricular biopsy sampling using a minimally invasive trans-thoracic approach in adult dogs DW Donker, JG Maessen, RL Spätjens, T van der Nagel, M de Jong, ... Pflügers Archiv-European Journal of Physiology 454 (6), 1043-1051, 2007 | 3 | 2007 |
Accumulation of slow delayed rectifier K+ current (I-Ks) in canine ventricular myocytes M Stengl, MA Vos, R Spatjens, KR Sipido, PGA Volders BIOPHYSICAL JOURNAL 82 (1), 606A-606A, 2002 | 2 | 2002 |
Cardiomyocyte cell cycle activity and function is under the control of miR-125a R Verjans, L Braga, M Rech, S Beijnsberger, P Carai, R Spatjens, ... Cardiovascular Research 114 (suppl_1), S18-S18, 2018 | 1 | 2018 |