Affibody molecules: engineered proteins for therapeutic, diagnostic and biotechnological applications J Löfblom, J Feldwisch, V Tolmachev, J Carlsson, S Ståhl, FY Frejd FEBS letters 584 (12), 2670-2680, 2010 | 764 | 2010 |
Affibody molecules in biotechnological and medical applications S Ståhl, T Gräslund, AE Karlström, FY Frejd, PÅ Nygren, J Löfblom Trends in biotechnology 35 (8), 691-712, 2017 | 347 | 2017 |
Optimizing membrane protein overexpression in the Escherichia coli strain Lemo21 (DE3) S Schlegel, J Löfblom, C Lee, A Hjelm, M Klepsch, M Strous, D Drew, ... Journal of molecular biology 423 (4), 648-659, 2012 | 196 | 2012 |
Optimization of electroporation‐mediated transformation: Staphylococcus carnosus as model organism J Löfblom, N Kronqvist, M Uhlén, S Ståhl, H Wernérus Journal of applied microbiology 102 (3), 736-747, 2007 | 194 | 2007 |
Non-immunoglobulin based protein scaffolds J Löfblom, FY Frejd, S Ståhl Current opinion in biotechnology 22 (6), 843-848, 2011 | 177 | 2011 |
Bacterial display in combinatorial protein engineering J Löfblom Biotechnology journal 6 (9), 1115-1129, 2011 | 140 | 2011 |
Epitope mapping of antibodies using bacterial surface display J Rockberg, J Löfblom, B Hjelm, M Uhlén, S Ståhl Nature methods 5 (12), 1039-1045, 2008 | 131 | 2008 |
A novel affinity protein selection system based on staphylococcal cell surface display and flow cytometry N Kronqvist, J Löfblom, A Jonsson, H Wernérus, S Ståhl Protein Engineering, Design & Selection 21 (4), 247-255, 2008 | 106 | 2008 |
Combining phage and staphylococcal surface display for generation of ErbB3-specific Affibody molecules N Kronqvist, M Malm, L Göstring, E Gunneriusson, M Nilsson, ... Protein Engineering, Design & Selection 24 (4), 385-396, 2011 | 91 | 2011 |
Inhibiting HER3-mediated tumor cell growth with affibody molecules engineered to low picomolar affinity by position-directed error-prone PCR-like diversification M Malm, N Kronqvist, H Lindberg, L Gudmundsdotter, T Bass, FY Frejd, ... Plos one 8 (5), e62791, 2013 | 84 | 2013 |
Surface display of a single-domain antibody library on Gram-positive bacteria F Fleetwood, N Devoogdt, M Pellis, U Wernery, S Muyldermans, S Ståhl, ... Cellular and Molecular Life Sciences 70, 1081-1093, 2013 | 77 | 2013 |
Engineering of bispecific affinity proteins with high affinity for ERBB2 and adaptable binding to albumin J Nilvebrant, M Åstrand, M Georgieva-Kotseva, M Björnmalm, J Löfblom, ... PloS one 9 (8), e103094, 2014 | 73 | 2014 |
Affibody-mediated PET imaging of HER3 expression in malignant tumours M Rosestedt, KG Andersson, B Mitran, V Tolmachev, J Löfblom, A Orlova, ... Scientific reports 5 (1), 15226, 2015 | 70 | 2015 |
Engineering of a bispecific affibody molecule towards HER2 and HER3 by addition of an albumin‐binding domain allows for affinity purification and in vivo half‐life extension M Malm, T Bass, L Gudmundsdotter, M Lord, FY Frejd, S Ståhl, J Löfblom Biotechnology journal 9 (9), 1215-1222, 2014 | 69 | 2014 |
Fine affinity discrimination by normalized fluorescence activated cell sorting in staphylococcal surface display J Löfblom, H Wernérus, S Ståhl FEMS microbiology letters 248 (2), 189-198, 2005 | 69 | 2005 |
Optimal composition and position of histidine-containing tags improves biodistribution of 99mTc-labeled DARPin G3 A Vorobyeva, A Schulga, E Konovalova, R Güler, J Löfblom, M Sandström, ... Scientific Reports 9 (1), 9405, 2019 | 64 | 2019 |
Staphylococcus carnosus: from starter culture to protein engineering platform J Löfblom, R Rosenstein, MT Nguyen, S Ståhl, F Götz Applied microbiology and biotechnology 101, 8293-8307, 2017 | 64 | 2017 |
PET imaging of epidermal growth factor receptor expression in tumours using 89Zr-labelled ZEGFR: 2377 affibody molecules J Garousi, KG Andersson, B Mitran, ML Pichl, S Ståhl, A Orlova, J Löfblom, ... International journal of oncology 48 (4), 1325-1332, 2016 | 59 | 2016 |
Engineering bispecificity into a single albumin-binding domain J Nilvebrant, T Alm, S Hober, J Löfblom PLoS One 6 (10), e25791, 2011 | 58 | 2011 |
An engineered affibody molecule with pH-dependent binding to FcRn mediates extended circulatory half-life of a fusion protein J Seijsing, M Lindborg, I Höidén-Guthenberg, H Bönisch, E Guneriusson, ... Proceedings of the National Academy of Sciences 111 (48), 17110-17115, 2014 | 57 | 2014 |