Ca2+ sparks activate K+ and Cl− channels, resulting in spontaneous transient currents in guinea‐pig tracheal myocytes R ZhuGe, SM Sims, RA Tuft, KE Fogarty, JV Walsh Jr The Journal of physiology 513 (3), 711-718, 1998 | 200 | 1998 |
Extraoral bitter taste receptors in health and disease P Lu, CH Zhang, LM Lifshitz, R ZhuGe Journal of General Physiology 149 (2), 181-197, 2017 | 186 | 2017 |
The Influence of Sarcoplasmic Reticulum Ca2+ Concentration on Ca2+ Sparks and Spontaneous Transient Outward Currents in Single Smooth Muscle Cells R ZhuGe, RA Tuft, KE Fogarty, K Bellve, FS Fay, JV Walsh Jr The Journal of general physiology 113 (2), 215-228, 1999 | 161 | 1999 |
The cellular and molecular basis of bitter tastant-induced bronchodilation CH Zhang, LM Lifshitz, KF Uy, M Ikebe, KE Fogarty, R ZhuGe PLoS biology 11 (3), e1001501, 2013 | 148 | 2013 |
Spontaneous transient outward currents arise from microdomains where BK channels are exposed to a mean Ca2+ concentration on the order of 10 μM during a Ca2+ spark R ZhuGe, KE Fogarty, RA Tuft, JV Walsh Jr The Journal of general physiology 120 (1), 15-27, 2002 | 131 | 2002 |
Ca2+ syntillas, miniature Ca2+ release events in terminals of hypothalamic neurons, are increased in frequency by depolarization in the absence of Ca2+ influx V De Crescenzo, R ZhuGe, C Velázquez-Marrero, LM Lifshitz, E Custer, ... Journal of Neuroscience 24 (5), 1226-1235, 2004 | 99 | 2004 |
Dynamics of Signaling between Ca2+ Sparks and Ca2+- Activated K+ Channels Studied with a Novel Image-Based Method for Direct Intracellular Measurement of … R ZhuGe, KE Fogarty, RA Tuft, LM Lifshitz, K Sayar, JV Walsh Jr The Journal of general physiology 116 (6), 845-864, 2000 | 94 | 2000 |
The Transmembrane Protein 16A Ca2+-activated Cl− Channel in Airway Smooth Muscle Contributes to Airway Hyperresponsiveness CH Zhang, Y Li, W Zhao, LM Lifshitz, H Li, BD Harfe, MS Zhu, R ZhuGe American journal of respiratory and critical care medicine 187 (4), 374-381, 2013 | 81 | 2013 |
OR14I1 is a receptor for the human cytomegalovirus pentameric complex and defines viral epithelial cell tropism E Xiaofei, P Meraner, P Lu, JM Perreira, AM Aker, WM McDougall, ... Proceedings of the National Academy of Sciences of the United States of …, 2019 | 78 | 2019 |
A Close Association of RyRs with Highly Dense Clusters of Ca2+-activated Cl− Channels Underlies the Activation of STICs by Ca2+ Sparks in Mouse Airway … R Bao, LM Lifshitz, RA Tuft, K Bellvé, KE Fogarty, R ZhuGe The Journal of general physiology 132 (1), 145-160, 2008 | 67 | 2008 |
Ca2+ sparks act as potent regulators of excitation-contraction coupling in airway smooth muscle R ZhuGe, R Bao, KE Fogarty, LM Lifshitz Journal of Biological Chemistry 285 (3), 2203-2210, 2010 | 54 | 2010 |
Dihydropyridine receptors and type 1 ryanodine receptors constitute the molecular machinery for voltage-induced Ca2+ release in nerve terminals V De Crescenzo, KE Fogarty, R ZhuGe, RA Tuft, LM Lifshitz, J Carmichael, ... Journal of Neuroscience 26 (29), 7565-7574, 2006 | 52 | 2006 |
Activation of BK channels may not be required for bitter tastant–induced bronchodilation CH Zhang, C Chen, LM Lifshitz, KE Fogarty, MS Zhu, R ZhuGe Nature medicine 18 (5), 648-650, 2012 | 51 | 2012 |
Ca2+ spark sites in smooth muscle cells are numerous and differ in number of ryanodine receptors, large-conductance K+ channels, and coupling ratio between … R ZhuGe, KE Fogarty, SP Baker, JG McCarron, RA Tuft, LM Lifshitz, ... American Journal of Physiology-Cell Physiology 287 (6), C1577-C1588, 2004 | 47 | 2004 |
Spatial organization of RYRs and BK channels underlying the activation of STOCs by Ca2+ sparks in airway myocytes LM Lifshitz, JD Carmichael, FA Lai, V Sorrentino, K Bellvé, KE Fogarty, ... Journal of General Physiology 138 (2), 195-209, 2011 | 44 | 2011 |
Inflammatory mediators mediate airway smooth muscle contraction through a G protein-coupled receptor–transmembrane protein 16A–voltage-dependent Ca2+ channel axis and … P Wang, W Zhao, J Sun, T Tao, X Chen, YY Zheng, CH Zhang, Z Chen, ... Journal of Allergy and Clinical Immunology 141 (4), 1259-1268. e11, 2018 | 38 | 2018 |
Bitter taste receptors as targets for tocolytics in preterm labor therapy K Zheng, P Lu, E Delpapa, K Bellve, R Deng, JC Condon, K Fogarty, ... The FASEB Journal 31 (9), 4037, 2017 | 37 | 2017 |
The molecular basis of the genesis of basal tone in internal anal sphincter CH Zhang, P Wang, DH Liu, CP Chen, W Zhao, X Chen, C Chen, WQ He, ... Nature communications 7 (1), 11358, 2016 | 36 | 2016 |
Syntillas release Ca2+ at a site different from the microdomain where exocytosis occurs in mouse chromaffin cells R ZhuGe, V DeCrescenzo, V Sorrentino, FA Lai, RA Tuft, LM Lifshitz, ... Biophysical journal 90 (6), 2027-2037, 2006 | 36 | 2006 |
A segment of 97 amino acids within the translocation domain of Clostridium difficile toxin B is essential for toxicity Y Zhang, L Shi, S Li, Z Yang, C Standley, Z Yang, R ZhuGe, T Savidge, ... PloS one 8 (3), e58634, 2013 | 27 | 2013 |