Preventive empagliflozin activity on acute acetic acid-induced ulcerative colitis in rats via modulation of SIRT-1/PI3K/AKT pathway and improving colon barrier MS Zaghloul, M Elshal, ME Abdelmageed Environmental Toxicology and Pharmacology 91, 103833, 2022 | 21 | 2022 |
Retinoic acid modulates IL-4, IL-10 and MCP-1 pathways in immune mediated hepatitis and interrupts CD4+ T cells infiltration M Elshal, N Abu-Elsaad, A El-Karef, T Ibrahim International immunopharmacology 75, 105808, 2019 | 20 | 2019 |
The multi-kinase inhibitor pazopanib targets hepatic stellate cell activation and apoptosis alleviating progression of liver fibrosis M Elshal, N Abu-Elsaad, A El-Karef, TM Ibrahim Naunyn-Schmiedeberg's archives of pharmacology 388, 1293-1304, 2015 | 16 | 2015 |
Diacerein counteracts acetaminophen-induced hepatotoxicity in mice via targeting NLRP3/caspase-1/IL-1β and IL-4/MCP-1 signaling pathways M Elshal, ME Abdelmageed Archives of pharmacal research 45 (3), 142-158, 2022 | 13 | 2022 |
Escin suppresses immune cell infiltration and selectively modulates Nrf2/HO-1, TNF-α/JNK, and IL-22/STAT3 signaling pathways in concanavalin A-induced autoimmune hepatitis in mice M Elshal, SH Hazem Inflammopharmacology 30 (6), 2317-2329, 2022 | 10 | 2022 |
Relative importance of different elements of mitochondrial oxidative phosphorylation in maintaining the barrier integrity of retinal endothelial cells: Implications for … S Eltanani, T Yumnamcha, A Gregory, M Elshal, M Shawky, AS Ibrahim Cells 11 (24), 4128, 2022 | 6 | 2022 |
Etanercept attenuates immune-mediated hepatitis induced by concanavalin A via differential regulation of the key effector cytokines of CD4+ T cells M Elshal, N Abu-Elsaad, A El-Karef, T Ibrahim Life Sciences 277, 119618, 2021 | 6 | 2021 |
Design, synthesis, and biological investigation of oxadiazolyl, thiadiazolyl, and pyrimidinyl linked antipyrine derivatives as potential non-acidic anti-inflammatory agents MM Al-Sanea, A Hamdi, S Brogi, S S. Tawfik, DIA Othman, M Elshal, ... Journal of enzyme inhibition and medicinal chemistry 38 (1), 2162511, 2023 | 5 | 2023 |
Modulation of the crosstalk between Keap1/Nrf2/HO-1 and NF-κB signaling pathways by Tomatidine protects against inflammation/oxidative stress-driven fulminant hepatic failure … WH Abdulaal, UM Omar, M Zeyadi, DS El-Agamy, NA Alhakamy, ... International Immunopharmacology 130, 111732, 2024 | 2 | 2024 |
Bioactivity of Eriocephalus africanus essential oil against concanavalin A-induced hepatitis via suppressing immune cell infiltration, inhibiting TNF-α/NF-κB and IFN-γ/STAT1 … A Haikal, AA Galala, M Elshal, Y Amen, AA Gohar Journal of Ethnopharmacology 318, 117000, 2024 | 2 | 2024 |
Renoprotective effect of diacetylrhein on diclofenac-induced acute kidney injury in rats via modulating Nrf2/NF-κB/NLRP3/GSDMD signaling pathways AN Mansoure, M Elshal, MG Helal Food and Chemical Toxicology 187, 114637, 2024 | 1 | 2024 |
Inhibitory effect of diacerein on diclofenac-induced acute nephrotoxicity in rats via modulating SIRT1/HIF-1α/NF-κB and SIRT1/p53 regulatory axes AN Mansoure, M Elshal, MG Helal International Immunopharmacology 131, 111776, 2024 | 1 | 2024 |
Targeting Nrf2/HO-1 and NF-κB/TNF-α signaling pathways with empagliflozin protects against atrial fibrillation-induced acute kidney injury in rats H Badreldin, A El-Karef, T Ibrahim, M Elshal Toxicology, 153879, 2024 | | 2024 |