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Joshua Chiou
Joshua Chiou
在 pfizer.com 的电子邮件经过验证 - 首页
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引用次数
引用次数
年份
Single-cell meta-analysis of SARS-CoV-2 entry genes across tissues and demographics
C Muus, MD Luecken, G Eraslan, L Sikkema, A Waghray, G Heimberg, ...
Nature medicine 27 (3), 546-559, 2021
555*2021
Type 2 diabetes genetic loci informed by multi-trait associations point to disease mechanisms and subtypes: a soft clustering analysis
MS Udler, J Kim, M von Grotthuss, S Bonàs-Guarch, JB Cole, J Chiou, ...
PLoS medicine 15 (9), e1002654, 2018
440*2018
Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation
A Mahajan, CN Spracklen, W Zhang, MCY Ng, LE Petty, H Kitajima, ...
Nature genetics 54 (5), 560-572, 2022
3382022
An atlas of dynamic chromatin landscapes in mouse fetal development
DU Gorkin, I Barozzi, Y Zhao, Y Zhang, H Huang, AY Lee, B Li, J Chiou, ...
Nature 583 (7818), 744-751, 2020
2842020
A single-cell atlas of chromatin accessibility in the human genome
K Zhang, JD Hocker, M Miller, X Hou, J Chiou, OB Poirion, Y Qiu, YE Li, ...
Cell 184 (24), 5985-6001. e19, 2021
2332021
Interpreting type 1 diabetes risk with genetics and single-cell epigenomics
J Chiou, RJ Geusz, ML Okino, JY Han, M Miller, R Melton, E Beebe, ...
Nature 594 (7863), 398-402, 2021
2152021
Plasma proteomic associations with genetics and health in the UK Biobank
BB Sun, J Chiou, M Traylor, C Benner, YH Hsu, TG Richardson, ...
Nature 622 (7982), 329-338, 2023
210*2023
Single-cell multiomic profiling of human lungs reveals cell-type-specific and age-dynamic control of SARS-CoV2 host genes
A Wang*, J Chiou*, OB Poirion*, J Buchanan*, MJ Valdez*, JM Verheyden, ...
Elife 9, e62522, 2020
165*2020
Illuminating the Onco-GPCRome: Novel G protein–coupled receptor-driven oncocrine networks and targets for cancer immunotherapy
V Wu, H Yeerna, N Nohata, J Chiou, O Harismendy, F Raimondi, A Inoue, ...
Journal of biological chemistry 294 (29), 11062-11086, 2019
1562019
Single-cell chromatin accessibility identifies pancreatic islet cell type–and state-specific regulatory programs of diabetes risk
J Chiou*, C Zeng*, Z Cheng, JY Han, M Schlichting, M Miller, R Mendez, ...
Nature genetics 53 (4), 455-466, 2021
1372021
An atlas of gene regulatory elements in adult mouse cerebrum
YE Li, S Preissl, X Hou, Z Zhang, K Zhang, Y Qiu, OB Poirion, B Li, ...
Nature 598 (7879), 129-136, 2021
1262021
Systematic analysis of binding of transcription factors to noncoding variants
J Yan, Y Qiu, AM Ribeiro dos Santos, Y Yin, YE Li, N Vinckier, N Nariai, ...
Nature 591 (7848), 147-151, 2021
1062021
The long noncoding RNA ROCKI regulates inflammatory gene expression
Q Zhang, TC Chao, VS Patil, Y Qin, SK Tiwari, J Chiou, A Dobin, CM Tsai, ...
The EMBO journal 38 (8), e100041, 2019
992019
Pancreatic islet chromatin accessibility and conformation reveals distal enhancer networks of type 2 diabetes risk
WW Greenwald*, J Chiou*, J Yan*, Y Qiu*, N Dai*, A Wang, N Nariai, ...
Nature communications 10 (1), 2078, 2019
962019
Common DNA sequence variation influences 3-dimensional conformation of the human genome
DU Gorkin, Y Qiu, M Hu, K Fletez-Brant, T Liu, AD Schmitt, A Noor, ...
Genome biology 20, 1-25, 2019
792019
Cardiac cell type–specific gene regulatory programs and disease risk association
JD Hocker, OB Poirion, F Zhu, J Buchanan, K Zhang, J Chiou, TM Wang, ...
Science advances 7 (20), eabf1444, 2021
772021
Shared genetic risk contributes to type 1 and type 2 diabetes etiology
A Aylward*, J Chiou*, ML Okino, N Kadakia, KJ Gaulton
Human Molecular Genetics, 2018
552018
Sequence logic at enhancers governs a dual mechanism of endodermal organ fate induction by FOXA pioneer factors
RJ Geusz, A Wang, DK Lam, NK Vinckier, KD Alysandratos, DA Roberts, ...
Nature communications 12 (1), 6636, 2021
442021
Mutations and variants of ONECUT1 in diabetes
A Philippi, S Heller, IG Costa, V Senée, M Breunig, Z Li, G Kwon, ...
Nature Medicine 27 (11), 1928-1940, 2021
322021
High-throughput genetic clustering of type 2 diabetes loci reveals heterogeneous mechanistic pathways of metabolic disease
H Kim, KE Westerman, K Smith, J Chiou, JB Cole, T Majarian, ...
Diabetologia 66 (3), 495-507, 2023
272023
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