| Bile acids and the gut microbiota: metabolic interactions and impacts on disease SL Collins, JG Stine, JE Bisanz, CD Okafor, AD Patterson Nature Reviews Microbiology 21 (4), 236-247, 2023 | 211 | 2023 |
| RNA with iron(II) as a cofactor catalyses electron transfer C Hsiao, IC Chou, CD Okafor, JC Bowman, EB O'neill, SS Athavale, ... Nature Chemistry 5 (6), 525-528, 2013 | 77 | 2013 |
| RNA–magnesium–protein interactions in large ribosomal subunit AS Petrov, CR Bernier, C Hsiao, CD Okafor, E Tannenbaum, J Stern, ... The journal of physical chemistry B 116 (28), 8113-8120, 2012 | 55 | 2012 |
| Structure and assembly of the diiron cofactor in the heme-oxygenase–like domain of the N-nitrosourea–producing enzyme SznF MJ McBride, SR Pope, K Hu, CD Okafor, EP Balskus, JM Bollinger Jr, ... Proceedings of the National Academy of Sciences 118 (4), e2015931118, 2021 | 36 | 2021 |
| Structural and dynamics comparison of thermostability in ancient, modern, and consensus elongation factor Tus CD Okafor, MC Pathak, CE Fagan, NC Bauer, MF Cole, EA Gaucher, ... Structure 26 (1), 118-129. e3, 2018 | 30 | 2018 |
| Iron mediates catalysis of nucleic acid processing enzymes: support for Fe (II) as a cofactor before the great oxidation event CD Okafor, KA Lanier, AS Petrov, SS Athavale, JC Bowman, NV Hud, ... Nucleic Acids Research 45 (7), 3634-3642, 2017 | 30 | 2017 |
| The first crystal structure of a DNA-free nuclear receptor DNA binding domain sheds light on DNA-driven allostery in the glucocorticoid receptor F Frank, CD Okafor, EA Ortlund Scientific reports 8 (1), 13497, 2018 | 29 | 2018 |
| Crystal Structures of the Nuclear Receptor, Liver Receptor Homolog 1, Bound to Synthetic Agonists*♦ SG Mays, CD Okafor, RJ Whitby, D Goswami, J Stec, AR Flynn, ... Journal of Biological Chemistry 291 (49), 25281-25291, 2016 | 29 | 2016 |
| Development of the first low nanomolar liver receptor homolog-1 agonist through structure-guided design SG Mays, AR Flynn, JL Cornelison, CD Okafor, H Wang, G Wang, ... Journal of medicinal chemistry 62 (24), 11022-11034, 2019 | 28 | 2019 |
| Ribosomal small subunit domains radiate from a central core B Gulen, AS Petrov, CD Okafor, D Vander Wood, EB O’Neill, NV Hud, ... Scientific reports 6 (1), 20885, 2016 | 28 | 2016 |
| Structure and dynamics of the liver receptor homolog 1–PGC1α complex SG Mays, CD Okafor, ML Tuntland, RJ Whitby, V Dharmarajan, J Stec, ... Molecular pharmacology 92 (1), 1-11, 2017 | 24 | 2017 |
| Cutting in-line with iron: ribosomal function and non-oxidative RNA cleavage R Guth-Metzler, MS Bray, M Frenkel-Pinter, S Suttapitugsakul, ... Nucleic acids research 48 (15), 8663-8674, 2020 | 22 | 2020 |
| Structural analysis of the glucocorticoid receptor ligand-binding domain in complex with triamcinolone acetonide and a fragment of the atypical coregulator, small heterodimer … ER Weikum, CD Okafor, EH D’Agostino, JK Colucci, EA Ortlund Molecular pharmacology 92 (1), 12-21, 2017 | 22 | 2017 |
| Nonenzymatic ligation of DNA with a reversible step and a final linkage that can be used in PCR AE Engelhart, BJ Cafferty, CD Okafor, MC Chen, LD Williams, DG Lynn, ... ChemBioChem 13 (8), 1121-1124, 2012 | 18 | 2012 |
| Allosteric regulation of thioesterase superfamily member 1 by lipid sensor domain binding fatty acids and lysophosphatidylcholine MC Tillman, N Imai, Y Li, M Khadka, CD Okafor, P Juneja, A Adhiyaman, ... Proceedings of the National Academy of Sciences 117 (36), 22080-22089, 2020 | 17 | 2020 |
| Inhibitors of ApiAP2 protein DNA binding exhibit multistage activity against Plasmodium parasites TJ Russell, EK De Silva, VM Crowley, K Shaw-Saliba, N Dube, G Josling, ... PLoS pathogens 18 (10), e1010887, 2022 | 13 | 2022 |
| Molecular Recognition of Watson–Crick‐Like Purine–Purine Base Pairs R Buckley, CD Enekwa, LD Williams, NV Hud ChemBioChem 12 (14), 2155-2158, 2011 | 13 | 2011 |
| A phospholipid mimetic targeting LRH-1 ameliorates colitis SG Mays, EH D’Agostino, AR Flynn, X Huang, G Wang, X Liu, EJ Millings, ... Cell Chemical Biology 29 (7), 1174-1186. e7, 2022 | 9 | 2022 |
| Rewiring ancient residue interaction networks drove the evolution of specificity in steroid receptors CD Okafor, D Hercules, SA Kell, EA Ortlund Structure 28 (2), 196-205. e3, 2020 | 9 | 2020 |
| Ligand-induced allosteric effects governing SR signaling CD Okafor, JK Colucci, EA Ortlund Nuclear Receptor Research 6, 1382, 2019 | 9 | 2019 |
