Inhibition of Ataxia Telangiectasia‐and Rad3‐Related Function Abrogates the In Vitro and In Vivo Tumorigenicity of Human Colon Cancer Cells Through Depletion of the CD133+ … E Gallmeier, PC Hermann, MT Mueller, JG Machado, A Ziesch, ... Stem Cells 29 (3), 418-429, 2011 | 115 | 2011 |
Overexpression of heat shock protein 27 (HSP 27) increases gemcitabine sensitivity in pancreatic cancer cells through S‐phase arrest and apoptosis Y Guo, A Ziesch, S Hocke, E Kampmann, S Ochs, EN De Toni, B Göke, ... Journal of cellular and molecular medicine 19 (2), 340-350, 2015 | 56 | 2015 |
Heat shock protein 27 as a prognostic and predictive biomarker in pancreatic ductal adenocarcinoma C Schäfer, H Seeliger, DC Bader, G Assmann, D Buchner, Y Guo, ... Journal of cellular and molecular medicine 16 (8), 1776-1791, 2012 | 53 | 2012 |
The PI3K inhibitor copanlisib synergizes with sorafenib to induce cell death in hepatocellular carcinoma L Ye, J Mayerle, A Ziesch, FP Reiter, AL Gerbes, EN De Toni Cell death discovery 5 (1), 86, 2019 | 52 | 2019 |
A synthetic lethal screen identifies ATR-inhibition as a novel therapeutic approach for POLD1-deficient cancers S Hocke, Y Guo, A Job, M Orth, A Ziesch, K Lauber, EN De Toni, ... Oncotarget 7 (6), 7080, 2016 | 45 | 2016 |
Genetic inactivation of the Fanconi anemia gene FANCC identified in the hepatocellular carcinoma cell line HuH-7 confers sensitivity towards DNA-interstrand … A Palagyi, K Neveling, U Plinninger, A Ziesch, BS Targosz, GU Denk, ... Molecular cancer 9, 1-15, 2010 | 41 | 2010 |
Genetic targeting of B-RafV600E affects survival and proliferation and identifies selective agents against BRAF-mutant colorectal cancer cells B Hirschi, E Gallmeier, A Ziesch, M Marschall, FT Kolligs Molecular Cancer 13, 1-12, 2014 | 28 | 2014 |
Antifibrotic effects of hypocalcemic vitamin D analogs in murine and human hepatic stellate cells and in the CCl4 mouse model FP Reiter, L Ye, F Bösch, R Wimmer, R Artmann, A Ziesch, V Kanitz, ... Laboratory investigation 99 (12), 1906-1917, 2019 | 25 | 2019 |
Predictors of ribociclib-mediated antitumour effects in native and sorafenib-resistant human hepatocellular carcinoma cells FP Reiter, G Denk, A Ziesch, A Ofner, R Wimmer, S Hohenester, ... Cellular Oncology 42, 705-715, 2019 | 22 | 2019 |
Inactivation of BRCA2 in human cancer cells identifies a subset of tumors with enhanced sensitivity towards death receptormediated apoptosis EN De Toni, A Ziesch, A Rizzani, HP Török, S Hocke, S Lü, SC Wang, ... Oncotarget 7 (8), 9477, 2016 | 11 | 2016 |
Prognostic significance and functional relevance of olfactomedin 4 in early-stage hepatocellular carcinoma L Ye, L Kriegl, FP Reiter, SM Munker, T Itzel, A Teufel, A Ziesch, HP Török, ... Clinical and Translational Gastroenterology 11 (1), e00124, 2020 | 10 | 2020 |
p70 ribosomal protein S6 kinase is a checkpoint of human hepatic stellate cell activation and liver fibrosis in mice FP Reiter, L Ye, A Ofner, TS Schiergens, A Ziesch, L Brandl, NB Khaled, ... Cellular and Molecular Gastroenterology and Hepatology 13 (1), 95-112, 2022 | 5 | 2022 |
The inhibition of YAP Signaling Prevents Chronic Biliary Fibrosis in the Abcb4-/-Model by Modulation of Hepatic Stellate Cell and Bile Duct Epithelium Cell Pathophysiology L Ye, A Ziesch, JS Schneider, A Ofner, H Nieß, G Denk, S Hohenester, ... Aging and Disease 15 (1), 338, 2024 | 3 | 2024 |
Comparative response of HCC Cells to TKIs: modified in vitro testing and descriptive expression analysis P Sagmeister, J Daza, A Ofner, A Ziesch, L Ye, N Ben Khaled, M Ebert, ... Journal of Hepatocellular Carcinoma, 595-607, 2022 | 2 | 2022 |
The PI3K inhibitor copanlisib synergizes with sorafenib to induce cell death in hepatocellular carcinoma (HCC) L Ye, J Mayerle, A Ziesch, K Wei, AL Gerbes, EN De Toni Zeitschrift für Gastroenterologie 56 (05), G3, 2018 | 1 | 2018 |
Comparative response of HCC cells to sorafenib, lenvatinib, cabozantinib and regorafenib; descriptive expression analysis P Sagmeister, J Daza, A Ofner, A Ziesch, L Ye, N Ben-Khaled, FP Reiter, ... Zeitschrift für Gastroenterologie 60 (01), P 4.26, 2022 | | 2022 |
Synergismus von Poly (ADP-ribose)-Polymerase Inhibitoren und Todesrezeptor Agonisten in Abhängigkeit des BRCA2-Mutationsstatus NB Khaled, K Hammer, A Ziesch, A Ofner, L Ye, I Piseddu, S Munker, ... Zeitschrift für Gastroenterologie 59 (08), A 243, 2021 | | 2021 |
Die pharmakologische Hemmung des Hippo-Signalweges reduziert die Entstehung der chronisch biliären Fibrose im Abcb4-/-Model durch eine Modulation der Aktivierung von … L Ye, A Ziesch, A Ofner, H Nieß, T Schiergens, G Denk, KN Ben, ... Zeitschrift für Gastroenterologie 59 (08), A 153, 2021 | | 2021 |
The inhibition of the YAP-1/CTGF pathway improves chronic biliary fibrosis in the Abcb4-/-model by modulation of hepatic stellate cell physiology L Ye, A Ziesch, A Ofner, TS Schiergens, G Denk, N Ben Khaled, ... JOURNAL OF HEPATOLOGY 75, S389-S389, 2021 | | 2021 |
Die Bedeutung des YAP-1/CTGF-Signalwegs für die Aktivierung von humanen hepatischen Sternzellen und für die Leberfibrogenese im Menschen L Ye, A Ziesch, T Schiergens, G Denk, D Mayr, R Artmann, AL Gerbes, ... Zeitschrift für Gastroenterologie 59 (06), 3, 2021 | | 2021 |