Targeting of the tumor suppressor GRHL3 by a miR-21-dependent proto-oncogenic network results in PTEN loss and tumorigenesis C Darido, SR Georgy, T Wilanowski, S Dworkin, A Auden, Q Zhao, ... Cancer cell 20 (5), 635-648, 2011 | 262 | 2011 |
Protease-activated receptors in the musculoskeletal system EJ Mackie, LH Loh, S Sivagurunathan, K Uaesoontrachoon, HJ Yoo, ... The international journal of biochemistry & cell biology 40 (6-7), 1169-1184, 2008 | 56 | 2008 |
Identification of a novel proto-oncogenic network in head and neck squamous cell carcinoma SR Georgy, M Cangkrama, S Srivastava, D Partridge, A Auden, S Dworkin, ... Journal of the National Cancer Institute 107 (9), djv152, 2015 | 50 | 2015 |
Grainyhead-like 3 regulation of endothelin-1 in the pharyngeal endoderm is critical for growth and development of the craniofacial skeleton S Dworkin, J Simkin, C Darido, DD Partridge, SR Georgy, J Caddy, ... Mechanisms of development 133, 77-90, 2014 | 49 | 2014 |
Midbrain-hindbrain boundary patterning and morphogenesis are regulated by diverse grainy head-like 2-dependent pathways S Dworkin, C Darido, SR Georgy, T Wilanowski, S Srivastava, F Ellett, ... Development 139 (3), 525-536, 2012 | 48 | 2012 |
The role of barrier genes in epidermal malignancy C Darido, SR Georgy, SM Jane Oncogene 35 (44), 5705-5712, 2016 | 38 | 2016 |
Stage-dependent therapeutic efficacy in PI3K/mTOR-driven squamous cell carcinoma of the skin C Darido, SR Georgy, C Cullinane, DD Partridge, R Walker, S Srivastava, ... Cell Death & Differentiation 25 (6), 1146-1159, 2018 | 35 | 2018 |
Two ancient gene families are critical for maintenance of the mammalian skin barrier in postnatal life M Cangkrama, C Darido, SR Georgy, D Partridge, A Auden, S Srivastava, ... Journal of Investigative Dermatology 136 (7), 1438-1448, 2016 | 35 | 2016 |
Proteinase-activated receptor-2 is required for normal osteoblast and osteoclast differentiation during skeletal growth and repair SR Georgy, CN Pagel, A Ghasem-Zadeh, RMD Zebaze, RN Pike, ... Bone 50 (3), 704-712, 2012 | 32 | 2012 |
Inactivation of Zeb1 in GRHL2-deficient mouse embryos rescues mid-gestation viability and secondary palate closure MR Carpinelli, ME De Vries, A Auden, T Butt, Z Deng, DD Partridge, ... Disease models & mechanisms 13 (3), dmm042218, 2020 | 28 | 2020 |
The proteasome inhibitor ixazomib inhibits the formation and growth of pulmonary and abdominal osteosarcoma metastases in mice MA Harris, MA Miles, TM Shekhar, C Cerra, SR Georgy, SD Ryan, ... Cancers 12 (5), 1207, 2020 | 20 | 2020 |
Proteinase‐activated receptor‐2 (PAR2) and mouse osteoblasts: Regulation of cell function and lack of specificity of PAR2‐activating peptides SR Georgy, CN Pagel, DM Wong, S Sivagurunathan, LH Loh, DE Myers, ... Clinical and Experimental Pharmacology and Physiology 37 (3), 328-336, 2010 | 16 | 2010 |
Grainyhead‐like 3 (Grhl3) deficiency in brain leads to altered locomotor activity and decreased anxiety‐like behaviors in aged mice S Dworkin, A Auden, DD Partridge, M Daglas, RL Medcalf, ... Developmental neurobiology 77 (6), 775-788, 2017 | 15 | 2017 |
SARS-CoV-2 mouse adaptation selects virulence mutations that cause TNF-driven age-dependent severe disease with human correlates SM Bader, JP Cooney, D Sheerin, G Taiaroa, L Harty, KC Davidson, ... Proceedings of the National Academy of Sciences 120 (32), e2301689120, 2023 | 12 | 2023 |
Identification of a Novel GRHL3/HOPX/Wnt/β-Catenin proto-oncogenic axis in squamous cell carcinoma of the esophagus SR Georgy, DR Rudiatmoko, A Auden, D Partridge, T Butt, S Srivastava, ... Cellular and molecular gastroenterology and hepatology 15 (5), 1051-1069, 2023 | 8 | 2023 |
Cross-species oncogenomics offers insight into human muscle-invasive bladder cancer K Wong, F Abascal, L Ludwig, H Aupperle-Lellbach, J Grassinger, ... Genome biology 24 (1), 191, 2023 | 7 | 2023 |
Necroptosis does not drive disease pathogenesis in a mouse infective model of SARS-CoV-2 in vivo S M. Bader, JP Cooney, R Bhandari, L Mackiewicz, M Dayton, D Sheerin, ... Cell Death & Disease 15 (1), 100, 2024 | 5 | 2024 |
Recent insights into the biology of Barrett's esophagus H Badgery, L Chong, E Iich, Q Huang, SR Georgy, DH Wang, M Read Annals of the New York Academy of Sciences 1481 (1), 198-209, 2020 | 5 | 2020 |
Advances in organoid technology for veterinary disease modeling B Chen, RF Slocombe, SR Georgy Frontiers in Veterinary Science 10, 1234628, 2023 | 2 | 2023 |
Early Endothelial Activation in a Mouse Model of Graft vs Host Disease Following Chemotherapy M Pereira, NT Lee, J Noonan, AEH Willcox, I Calvello, SR Georgy, ... Frontiers in Immunology 12, 708554, 2021 | 1 | 2021 |