Brain-region-specific organoids using mini-bioreactors for modeling ZIKV exposure X Qian, HN Nguyen, MM Song, C Hadiono, SC Ogden, C Hammack, ... Cell 165 (5), 1238-1254, 2016 | 2007 | 2016 |
LRRK2 mutant iPSC-derived DA neurons demonstrate increased susceptibility to oxidative stress HN Nguyen, B Byers, B Cord, A Shcheglovitov, J Byrne, P Gujar, K Kee, ... Cell stem cell 8 (3), 267-280, 2011 | 892 | 2011 |
Identification of small-molecule inhibitors of Zika virus infection and induced neural cell death via a drug repurposing screen M Xu, EM Lee, Z Wen, Y Cheng, WK Huang, X Qian, J Tcw, ... Nature medicine 22 (10), 1101-1107, 2016 | 700 | 2016 |
Human DAZL, DAZ and BOULE genes modulate primordial germ-cell and haploid gamete formation K Kee, VT Angeles, M Flores, HN Nguyen, RA Reijo Pera Nature 462 (7270), 222-225, 2009 | 568 | 2009 |
Synaptic dysregulation in a human iPS cell model of mental disorders Z Wen, HN Nguyen, Z Guo, MA Lalli, X Wang, Y Su, NS Kim, KJ Yoon, ... Nature 515 (7527), 414-418, 2014 | 555 | 2014 |
Generation of human brain region–specific organoids using a miniaturized spinning bioreactor X Qian, F Jacob, MM Song, HN Nguyen, H Song, G Ming Nature protocols 13 (3), 565-580, 2018 | 423 | 2018 |
DNA methylation presents distinct binding sites for human transcription factors S Hu, J Wan, Y Su, Q Song, Y Zeng, HN Nguyen, J Shin, E Cox, HS Rho, ... elife 2, e00726, 2013 | 377 | 2013 |
Isolation and characterization of pluripotent human spermatogonial stem cell-derived cells N Kossack, J Meneses, S Shefi, HN Nguyen, S Chavez, C Nicholas, ... Stem cells 27 (1), 138-149, 2009 | 370 | 2009 |
SNCA triplication Parkinson's patient's iPSC-derived DA neurons accumulate α-synuclein and are susceptible to oxidative stress B Byers, B Cord, HN Nguyen, B Schüle, L Fenno, PC Lee, K Deisseroth, ... PloS one 6 (11), e26159, 2011 | 340 | 2011 |
Endothelial cells derived from human iPSCS increase capillary density and improve perfusion in a mouse model of peripheral arterial disease AJ Rufaihah, NF Huang, S Jamé, JC Lee, HN Nguyen, B Byers, A De, ... Arteriosclerosis, thrombosis, and vascular biology 31 (11), e72-e79, 2011 | 315 | 2011 |
Telomere shortening and loss of self-renewal in dyskeratosis congenita induced pluripotent stem cells LFZ Batista, MF Pech, FL Zhong, HN Nguyen, KT Xie, AJ Zaug, SM Crary, ... Nature 474 (7351), 399-402, 2011 | 285 | 2011 |
Human germ cell differentiation from fetal-and adult-derived induced pluripotent stem cells S Panula, JV Medrano, K Kee, R Bergström, HN Nguyen, B Byers, ... Human molecular genetics 20 (4), 752-762, 2011 | 284 | 2011 |
Modeling a genetic risk for schizophrenia in iPSCs and mice reveals neural stem cell deficits associated with adherens junctions and polarity KJ Yoon, HN Nguyen, G Ursini, F Zhang, NS Kim, Z Wen, G Makri, ... Cell stem cell 15 (1), 79-91, 2014 | 261 | 2014 |
Using brain organoids to understand Zika virus-induced microcephaly X Qian, HN Nguyen, F Jacob, H Song, G Ming Development 144 (6), 952-957, 2017 | 237 | 2017 |
Divergent RNA‐binding proteins, DAZL and VASA, induce meiotic progression in human germ cells derived in vitro JV Medrano, C Ramathal, HN Nguyen, C Simon, RA Reijo Pera Stem cells 30 (3), 441-451, 2012 | 195 | 2012 |
Molecular signatures associated with ZIKV exposure in human cortical neural progenitors F Zhang, C Hammack, SC Ogden, Y Cheng, EM Lee, Z Wen, X Qian, ... Nucleic acids research 44 (18), 8610-8620, 2016 | 185 | 2016 |
Pluripotent cell lines and methods of use thereof RAR Pera, JW Langston, B Schüle, TD Palmer US Patent 8,669,048, 2014 | 124 | 2014 |
Enhanced generation of induced pluripotent stem cells from a subpopulation of human fibroblasts JA Byrne, HN Nguyen, RA Reijo Pera PloS one 4 (9), e7118, 2009 | 97 | 2009 |
Loss of CHFR in human mammary epithelial cells causes genomic instability by disrupting the mitotic spindle assembly checkpoint LM Privette, JF Weier, HN Nguyen, X Yu, EM Petty Neoplasia 10 (7), 643-652, 2008 | 48 | 2008 |
Precocious neuronal differentiation and disrupted oxygen responses in Kabuki syndrome GA Carosso, L Boukas, JJ Augustin, HN Nguyen, BL Winer, GH Cannon, ... JCI insight 4 (20), 2019 | 47 | 2019 |