Retinoic acid signaling pathways in development and diseases BC Das, P Thapa, R Karki, S Das, S Mahapatra, TC Liu, I Torregroza, ... Bioorganic & medicinal chemistry 22 (2), 673-683, 2014 | 310 | 2014 |
Boron chemicals in diagnosis and therapeutics BC Das, P Thapa, R Karki, C Schinke, S Das, S Kambhampati, ... Future medicinal chemistry 5 (6), 653-676, 2013 | 282 | 2013 |
Synthesis of 2, 6-diaryl-substituted pyridines and their antitumor activities JK Son, LX Zhao, A Basnet, P Thapa, R Karki, Y Na, Y Jahng, TC Jeong, ... European journal of medicinal chemistry 43 (4), 675-682, 2008 | 170 | 2008 |
2, 4, 6-Trisubstituted pyridines: Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure–activity relationship A Basnet, P Thapa, R Karki, Y Na, Y Jahng, BS Jeong, TC Jeong, CS Lee, ... Bioorganic & medicinal chemistry 15 (13), 4351-4359, 2007 | 159 | 2007 |
Solid self-nanoemulsifying drug delivery system (S-SNEDDS) containing phosphatidylcholine for enhanced bioavailability of highly lipophilic bioactive carotenoid lutein S Shanmugam, R Baskaran, P Balakrishnan, P Thapa, CS Yong, BK Yoo European Journal of Pharmaceutics and Biopharmaceutics 79 (2), 250-257, 2011 | 158 | 2011 |
Novel self-nanoemulsifying drug delivery system for enhanced solubility and dissolution of lutein JH Yoo, S Shanmugam, P Thapa, ES Lee, P Balakrishnan, R Baskaran, ... Archives of pharmacal research 33, 417-426, 2010 | 122 | 2010 |
Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure–activity relationship study of hydroxylated 2, 4-diphenyl-6-aryl pyridines R Karki, P Thapa, MJ Kang, TC Jeong, JM Nam, HL Kim, Y Na, WJ Cho, ... Bioorganic & medicinal chemistry 18 (9), 3066-3077, 2010 | 117 | 2010 |
Far-red light-activatable prodrug of paclitaxel for the combined effects of photodynamic therapy and site-specific paclitaxel chemotherapy P Thapa, M Li, M Bio, P Rajaputra, G Nkepang, Y Sun, S Woo, Y You Journal of medicinal chemistry 59 (7), 3204-3214, 2016 | 110 | 2016 |
A series of novel terpyridine-skeleton molecule derivants inhibit tumor growth and metastasis by targeting topoisomerases HB Kwon, C Park, KH Jeon, E Lee, SE Park, KY Jun, TM Kadayat, ... Journal of Medicinal Chemistry 58 (3), 1100-1122, 2015 | 102 | 2015 |
Chalcone and its analogs: Therapeutic and diagnostic applications in Alzheimer’s disease P Thapa, SP Upadhyay, WZ Suo, V Singh, P Gurung, ES Lee, R Sharma, ... Bioorganic chemistry 108, 104681, 2021 | 92 | 2021 |
NADPH oxidase inhibitors: a patent review JA Kim, GP Neupane, ES Lee, BS Jeong, BC Park, P Thapa Expert opinion on therapeutic patents 21 (8), 1147-1158, 2011 | 86 | 2011 |
Design, synthesis, and antitumor evaluation of 2, 4, 6-triaryl pyridines containing chlorophenyl and phenolic moiety P Thapa, R Karki, M Yun, TM Kadayat, E Lee, HB Kwon, Y Na, WJ Cho, ... European journal of medicinal chemistry 52, 123-136, 2012 | 78 | 2012 |
Dihydroxylated 2, 4, 6-triphenyl pyridines: Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure–activity relationship study R Karki, P Thapa, HY Yoo, TM Kadayat, PH Park, Y Na, E Lee, KH Jeon, ... European journal of medicinal chemistry 49, 219-228, 2012 | 73 | 2012 |
2-Thienyl-4-furyl-6-aryl pyridine derivatives: Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure–activity relationship study P Thapa, R Karki, U Thapa, Y Jahng, MJ Jung, JM Nam, Y Na, Y Kwon, ... Bioorganic & medicinal chemistry 18 (1), 377-386, 2010 | 73 | 2010 |
2, 6-Dithienyl-4-furyl pyridines: Synthesis, topoisomerase I and II inhibition, cytotoxicity, structure–activity relationship, and docking study A Basnet, P Thapa, R Karki, H Choi, JH Choi, M Yun, BS Jeong, Y Jahng, ... Bioorganic & medicinal chemistry letters 20 (1), 42-47, 2010 | 58 | 2010 |
Synthesis of 2, 4-diaryl chromenopyridines and evaluation of their topoisomerase I and II inhibitory activity, cytotoxicity, and structure–activity relationship U Thapa, P Thapa, R Karki, M Yun, JH Choi, Y Jahng, E Lee, KH Jeon, ... European journal of medicinal chemistry 46 (8), 3201-3209, 2011 | 57 | 2011 |
Synthesis of 2-(thienyl-2-yl or-3-yl)-4-furyl-6-aryl pyridine derivatives and evaluation of their topoisomerase I and II inhibitory activity, cytotoxicity, and structure … P Thapa, R Karki, H Choi, JH Choi, M Yun, BS Jeong, MJ Jung, JM Nam, ... Bioorganic & Medicinal Chemistry 18 (6), 2245-2254, 2010 | 52 | 2010 |
1-Isoindolinone scaffold-based natural products with a promising diverse bioactivity SP Upadhyay, P Thapa, R Sharma, M Sharma Fitoterapia 146, 104722, 2020 | 50 | 2020 |
Folate-PEG conjugates of a far-red light-activatable paclitaxel prodrug to improve selectivity toward folate receptor-positive cancer cells P Thapa, M Li, R Karki, M Bio, P Rajaputra, G Nkepang, S Woo, Y You ACS omega 2 (10), 6349-6360, 2017 | 41 | 2017 |
Synthesis, antitumor activity, and structure–activity relationship study of trihydroxylated 2, 4, 6-triphenyl pyridines as potent and selective topoisomerase II inhibitors R Karki, C Park, KY Jun, JG Jee, JH Lee, P Thapa, TM Kadayat, Y Kwon, ... European journal of medicinal chemistry 84, 555-565, 2014 | 37 | 2014 |