BRCA1 basal-like breast cancers originate from luminal epithelial progenitors and not from basal stem cells G Molyneux, FC Geyer, FA Magnay, A McCarthy, H Kendrick, R Natrajan, ... Cell stem cell 7 (3), 403-417, 2010 | 906 | 2010 |
Integrated molecular meta-analysis of 1,000 pediatric high-grade and diffuse intrinsic pontine glioma A Mackay, A Burford, D Carvalho, E Izquierdo, J Fazal-Salom, KR Taylor, ... Cancer cell 32 (4), 520-537. e5, 2017 | 885 | 2017 |
New brain tumor entities emerge from molecular classification of CNS-PNETs D Sturm, BA Orr, UH Toprak, V Hovestadt, DTW Jones, D Capper, M Sill, ... Cell 164 (5), 1060-1072, 2016 | 837 | 2016 |
FGFR1 Amplification Drives Endocrine Therapy Resistance and Is a Therapeutic Target in Breast Cancer N Turner, A Pearson, R Sharpe, M Lambros, F Geyer, MA Lopez-Garcia, ... Cancer research 70 (5), 2085-2094, 2010 | 819 | 2010 |
Genomic analysis of diffuse intrinsic pontine gliomas identifies three molecular subgroups and recurrent activating ACVR1 mutations P Buczkowicz, C Hoeman, P Rakopoulos, S Pajovic, L Letourneau, ... Nature genetics 46 (5), 451-456, 2014 | 628 | 2014 |
Histone H3F3A and HIST1H3B K27M mutations define two subgroups of diffuse intrinsic pontine gliomas with different prognosis and phenotypes D Castel, C Philippe, R Calmon, L Le Dret, N Truffaux, N Boddaert, ... Acta neuropathologica 130, 815-827, 2015 | 589 | 2015 |
Recurrent activating ACVR1 mutations in diffuse intrinsic pontine glioma KR Taylor, A Mackay, N Truffaux, YS Butterfield, O Morozova, C Philippe, ... Nature genetics 46 (5), 457-461, 2014 | 503 | 2014 |
Breast cancer molecular profiling with single sample predictors: a retrospective analysis B Weigelt, A Mackay, R A'hern, R Natrajan, DSP Tan, M Dowsett, ... The lancet oncology 11 (4), 339-349, 2010 | 482 | 2010 |
Integrative molecular profiling of triple negative breast cancers identifies amplicon drivers and potential therapeutic targets N Turner, MB Lambros, HM Horlings, A Pearson, R Sharpe, R Natrajan, ... Oncogene 29 (14), 2013-2023, 2010 | 463 | 2010 |
β-Catenin pathway activation in breast cancer is associated with triple-negative phenotype but not with CTNNB1 mutation FC Geyer, M Lacroix-Triki, K Savage, M Arnedos, MB Lambros, A MacKay, ... Modern pathology 24 (2), 209-231, 2011 | 424 | 2011 |
PTEN deficiency in endometrioid endometrial adenocarcinomas predicts sensitivity to PARP inhibitors KJ Dedes, D Wetterskog, AM Mendes-Pereira, R Natrajan, MB Lambros, ... Science translational medicine 2 (53), 53ra75-53ra75, 2010 | 406 | 2010 |
FGFR1 Emerges as a Potential Therapeutic Target for Lobular Breast Carcinomas JS Reis-Filho, PT Simpson, NC Turner, MB Lambros, C Jones, A Mackay, ... Clinical Cancer Research 12 (22), 6652-6662, 2006 | 342 | 2006 |
Histone H3. 3 mutations drive pediatric glioblastoma through upregulation of MYCN L Bjerke, A Mackay, M Nandhabalan, A Burford, A Jury, S Popov, DA Bax, ... Cancer discovery 3 (5), 512-519, 2013 | 331 | 2013 |
Expression profiling of purified normal human luminal and myoepithelial breast cells: identification of novel prognostic markers for breast cancer C Jones, A Mackay, A Grigoriadis, A Cossu, JS Reis-Filho, L Fulford, ... Cancer research 64 (9), 3037-3045, 2004 | 328 | 2004 |
EGFR amplification and lack of activating mutations in metaplastic breast carcinomas JS Reis‐Filho, C Pinheiro, MBK Lambros, F Milanezi, S Carvalho, ... The Journal of Pathology: A Journal of the Pathological Society of Great …, 2006 | 312 | 2006 |
ATRX loss promotes tumor growth and impairs nonhomologous end joining DNA repair in glioma C Koschmann, AA Calinescu, FJ Nunez, A Mackay, J Fazal-Salom, ... Science translational medicine 8 (328), 328ra28-328ra28, 2016 | 270 | 2016 |
Caveolin 1 is overexpressed and amplified in a subset of basal-like and metaplastic breast carcinomas: a morphologic, ultrastructural, immunohistochemical, and in situ … K Savage, MBK Lambros, D Robertson, RL Jones, C Jones, A Mackay, ... Clinical Cancer Research 13 (1), 90-101, 2007 | 252 | 2007 |
Molecular analysis reveals a genetic basis for the phenotypic diversity of metaplastic breast carcinomas FC Geyer, B Weigelt, R Natrajan, MBK Lambros, D de Biase, R Vatcheva, ... The Journal of Pathology: A Journal of the Pathological Society of Great …, 2010 | 241 | 2010 |
Does chromosome 17 centromere copy number predict polysomy in breast cancer? A fluorescence in situ hybridization and microarray‐based CGH analysis C Marchio, MB Lambros, P Gugliotta, LV Di Cantogno, C Botta, B Pasini, ... The Journal of Pathology: A Journal of the Pathological Society of Great …, 2009 | 228 | 2009 |
cDNA microarray analysis of genes associated with ERBB2 (HER2/neu) overexpression in human mammary luminal epithelial cells A Mackay, C Jones, T Dexter, RLA Silva, K Bulmer, A Jones, P Simpson, ... Oncogene 22 (17), 2680-2688, 2003 | 213 | 2003 |