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Alan Mackay
Alan Mackay
BioInformatician
在 icr.ac.uk 的电子邮件经过验证
标题
引用次数
引用次数
年份
BRCA1 basal-like breast cancers originate from luminal epithelial progenitors and not from basal stem cells
G Molyneux, FC Geyer, FA Magnay, A McCarthy, H Kendrick, R Natrajan, ...
Cell stem cell 7 (3), 403-417, 2010
9062010
Integrated molecular meta-analysis of 1,000 pediatric high-grade and diffuse intrinsic pontine glioma
A Mackay, A Burford, D Carvalho, E Izquierdo, J Fazal-Salom, KR Taylor, ...
Cancer cell 32 (4), 520-537. e5, 2017
8852017
New brain tumor entities emerge from molecular classification of CNS-PNETs
D Sturm, BA Orr, UH Toprak, V Hovestadt, DTW Jones, D Capper, M Sill, ...
Cell 164 (5), 1060-1072, 2016
8372016
FGFR1 Amplification Drives Endocrine Therapy Resistance and Is a Therapeutic Target in Breast Cancer
N Turner, A Pearson, R Sharpe, M Lambros, F Geyer, MA Lopez-Garcia, ...
Cancer research 70 (5), 2085-2094, 2010
8192010
Genomic analysis of diffuse intrinsic pontine gliomas identifies three molecular subgroups and recurrent activating ACVR1 mutations
P Buczkowicz, C Hoeman, P Rakopoulos, S Pajovic, L Letourneau, ...
Nature genetics 46 (5), 451-456, 2014
6282014
Histone H3F3A and HIST1H3B K27M mutations define two subgroups of diffuse intrinsic pontine gliomas with different prognosis and phenotypes
D Castel, C Philippe, R Calmon, L Le Dret, N Truffaux, N Boddaert, ...
Acta neuropathologica 130, 815-827, 2015
5892015
Recurrent activating ACVR1 mutations in diffuse intrinsic pontine glioma
KR Taylor, A Mackay, N Truffaux, YS Butterfield, O Morozova, C Philippe, ...
Nature genetics 46 (5), 457-461, 2014
5032014
Breast cancer molecular profiling with single sample predictors: a retrospective analysis
B Weigelt, A Mackay, R A'hern, R Natrajan, DSP Tan, M Dowsett, ...
The lancet oncology 11 (4), 339-349, 2010
4822010
Integrative molecular profiling of triple negative breast cancers identifies amplicon drivers and potential therapeutic targets
N Turner, MB Lambros, HM Horlings, A Pearson, R Sharpe, R Natrajan, ...
Oncogene 29 (14), 2013-2023, 2010
4632010
β-Catenin pathway activation in breast cancer is associated with triple-negative phenotype but not with CTNNB1 mutation
FC Geyer, M Lacroix-Triki, K Savage, M Arnedos, MB Lambros, A MacKay, ...
Modern pathology 24 (2), 209-231, 2011
4242011
PTEN deficiency in endometrioid endometrial adenocarcinomas predicts sensitivity to PARP inhibitors
KJ Dedes, D Wetterskog, AM Mendes-Pereira, R Natrajan, MB Lambros, ...
Science translational medicine 2 (53), 53ra75-53ra75, 2010
4062010
FGFR1 Emerges as a Potential Therapeutic Target for Lobular Breast Carcinomas
JS Reis-Filho, PT Simpson, NC Turner, MB Lambros, C Jones, A Mackay, ...
Clinical Cancer Research 12 (22), 6652-6662, 2006
3422006
Histone H3. 3 mutations drive pediatric glioblastoma through upregulation of MYCN
L Bjerke, A Mackay, M Nandhabalan, A Burford, A Jury, S Popov, DA Bax, ...
Cancer discovery 3 (5), 512-519, 2013
3312013
Expression profiling of purified normal human luminal and myoepithelial breast cells: identification of novel prognostic markers for breast cancer
C Jones, A Mackay, A Grigoriadis, A Cossu, JS Reis-Filho, L Fulford, ...
Cancer research 64 (9), 3037-3045, 2004
3282004
EGFR amplification and lack of activating mutations in metaplastic breast carcinomas
JS Reis‐Filho, C Pinheiro, MBK Lambros, F Milanezi, S Carvalho, ...
The Journal of Pathology: A Journal of the Pathological Society of Great …, 2006
3122006
ATRX loss promotes tumor growth and impairs nonhomologous end joining DNA repair in glioma
C Koschmann, AA Calinescu, FJ Nunez, A Mackay, J Fazal-Salom, ...
Science translational medicine 8 (328), 328ra28-328ra28, 2016
2702016
Caveolin 1 is overexpressed and amplified in a subset of basal-like and metaplastic breast carcinomas: a morphologic, ultrastructural, immunohistochemical, and in situ …
K Savage, MBK Lambros, D Robertson, RL Jones, C Jones, A Mackay, ...
Clinical Cancer Research 13 (1), 90-101, 2007
2522007
Molecular analysis reveals a genetic basis for the phenotypic diversity of metaplastic breast carcinomas
FC Geyer, B Weigelt, R Natrajan, MBK Lambros, D de Biase, R Vatcheva, ...
The Journal of Pathology: A Journal of the Pathological Society of Great …, 2010
2412010
Does chromosome 17 centromere copy number predict polysomy in breast cancer? A fluorescence in situ hybridization and microarray‐based CGH analysis
C Marchio, MB Lambros, P Gugliotta, LV Di Cantogno, C Botta, B Pasini, ...
The Journal of Pathology: A Journal of the Pathological Society of Great …, 2009
2282009
cDNA microarray analysis of genes associated with ERBB2 (HER2/neu) overexpression in human mammary luminal epithelial cells
A Mackay, C Jones, T Dexter, RLA Silva, K Bulmer, A Jones, P Simpson, ...
Oncogene 22 (17), 2680-2688, 2003
2132003
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