Functional transcription promoters at DNA double-strand breaks mediate RNA-driven phase separation of damage-response factors F Pessina, F Giavazzi, Y Yin, U Gioia, V Vitelli, A Galbiati, S Barozzi, ... Nature cell biology 21 (10), 1286-1299, 2019 | 283 | 2019 |
ATR-mediated phosphorylation of FANCI regulates dormant origin firing in response to replication stress YH Chen, MJK Jones, Y Yin, SB Crist, L Colnaghi, RJ Sims, E Rothenberg, ... Molecular cell 58 (2), 323-338, 2015 | 176 | 2015 |
CDK7 inhibition potentiates genome instability triggering anti-tumor immunity in small cell lung cancer H Zhang, CL Christensen, R Dries, MG Oser, J Deng, B Diskin, F Li, Y Pan, ... Cancer cell 37 (1), 37-54. e9, 2020 | 173 | 2020 |
An ATR and CHK1 kinase signaling mechanism that limits origin firing during unperturbed DNA replication TN Moiseeva, Y Yin, MJ Calderon, C Qian, S Schamus-Haynes, ... Proceedings of the National Academy of Sciences 116 (27), 13374-13383, 2019 | 131 | 2019 |
Kinetics and dynamics of DNA hybridization Y Yin, XS Zhao Accounts of Chemical Research 44 (11), 1172-1181, 2011 | 123 | 2011 |
Disruption of Ca2+i Homeostasis and Connexin 43 Hemichannel Function in the Right Ventricle Precedes Overt Arrhythmogenic Cardiomyopathy in Plakophilin-2 … JC Kim, M Perez-Hernandez, FJ Alvarado, SR Maurya, J Montnach, Y Yin, ... Circulation 140 (12), 1015-1030, 2019 | 100 | 2019 |
Dynamics of spontaneous flipping of a mismatched base in DNA duplex Y Yin, L Yang, G Zheng, C Gu, C Yi, C He, YQ Gao, XS Zhao Proceedings of the National Academy of Sciences 111 (22), 8043-8048, 2014 | 96 | 2014 |
XLF and APLF bind Ku80 at two remote sites to ensure DNA repair by non-homologous end joining C Nemoz, V Ropars, P Frit, A Gontier, P Drevet, J Yu, R Guérois, A Pitois, ... Nature structural & molecular biology 25 (10), 971-980, 2018 | 87 | 2018 |
Sequence-independent self-assembly of germ granule mRNAs into homotypic clusters T Trcek, TE Douglas, M Grosch, Y Yin, WVI Eagle, ER Gavis, H Shroff, ... Molecular cell 78 (5), 941-950. e12, 2020 | 70 | 2020 |
Single-molecule imaging reveals replication fork coupled formation of G-quadruplex structures hinders local replication stress signaling WTC Lee, Y Yin, MJ Morten, P Tonzi, PP Gwo, DC Odermatt, M Modesti, ... Nature communications 12 (1), 2525, 2021 | 67 | 2021 |
Translesion polymerase kappa-dependent DNA synthesis underlies replication fork recovery P Tonzi, Y Yin, CWT Lee, E Rothenberg, TT Huang elife 7, e41426, 2018 | 61 | 2018 |
Spatiotemporal dynamics of homologous recombination repair at single collapsed replication forks DR Whelan, WTC Lee, Y Yin, DM Ofri, K Bermudez-Hernandez, S Keegan, ... Nature Communications 9 (1), 3882, 2018 | 58 | 2018 |
PARP1-dependent recruitment of the FBXL10-RNF68-RNF2 ubiquitin ligase to sites of DNA damage controls H2A. Z loading G Rona, D Roberti, Y Yin, JK Pagan, H Homer, E Sassani, A Zeke, ... Elife 7, e38771, 2018 | 45 | 2018 |
Bridging of double-stranded breaks by the nonhomologous end-joining ligation complex is modulated by DNA end chemistry DA Reid, MP Conlin, Y Yin, HH Chang, G Watanabe, MR Lieber, ... Nucleic acids research 45 (4), 1872-1878, 2017 | 45 | 2017 |
A method for quantifying molecular interactions using stochastic modelling and super-resolution microscopy K Bermudez-Hernandez, S Keegan, DR Whelan, DA Reid, J Zagelbaum, ... Scientific reports 7 (1), 14882, 2017 | 35 | 2017 |
A two-step mechanism governing PARP1-DNA retention by PARP inhibitors H Xue, A Bhardwaj, Y Yin, C Fijen, A Ephstein, L Zhang, X Ding, ... Science advances 8 (36), eabq0414, 2022 | 27 | 2022 |
Panorama of DNA hairpin folding observed via diffusion-decelerated fluorescence correlation spectroscopy. Y Yin, P Wang, XX Yang, X Li, C He, XS Zhao Chemical communications (Cambridge, England) 48 (59), 7413, 2012 | 27 | 2012 |
Ultrafast data mining of molecular assemblies in multiplexed high-density super-resolution images Y Yin, WTC Lee, E Rothenberg Nature communications 10 (1), 119, 2019 | 25 | 2019 |
Anosmin1 shuttles Fgf to facilitate its diffusion, increase its local concentration, and induce sensory organs J Wang, Y Yin, S Lau, J Sankaran, E Rothenberg, T Wohland, ... Developmental cell 46 (6), 751-766. e12, 2018 | 24 | 2018 |
USP1-trapping lesions as a source of DNA replication stress and genomic instability KE Coleman, Y Yin, SKL Lui, S Keegan, D Fenyo, DJ Smith, ... Nature communications 13 (1), 1740, 2022 | 23 | 2022 |