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Darren Lyall Riley
Darren Lyall Riley
Seniour Lecturer, University of Pretoria
在 up.ac.za 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
Role of plants in anticancer drug discovery
J Khazir, BA Mir, L Pilcher, DL Riley
Phytochemistry letters 7, 173-181, 2014
2372014
Anticancer agents from diverse natural sources
J Khazir, DL Riley, LA Pilcher, P De-Maayer, BA Mir
Natural product communications 9 (11), 1934578X1400901130, 2014
1042014
Targeting Alzheimer's disease by investigating previously unexplored chemical space surrounding the cholinesterase inhibitor donepezil
DG van Greunen, W Cordier, M Nell, C van der Westhuyzen, ...
European Journal of Medicinal Chemistry 127, 671-690, 2017
492017
Application of reactor engineering concepts in continuous flow chemistry: a review
NC Neyt, DL Riley
Reaction Chemistry & Engineering 6 (8), 1295-1326, 2021
442021
Novel N-benzylpiperidine carboxamide derivatives as potential cholinesterase inhibitors for the treatment of Alzheimer's disease
DG van Greunen, CJ van der Westhuizen, W Cordier, M Nell, A Stander, ...
European Journal of Medicinal Chemistry 179, 680-693, 2019
302019
Batch–flow hybrid synthesis of the antipsychotic clozapine
NC Neyt, DL Riley
Reaction Chemistry & Engineering 3 (1), 17-24, 2018
282018
Landscape and opportunities for active pharmaceutical ingredient manufacturing in developing African economies
DL Riley, I Strydom, R Chikwamba, JL Panayides
Reaction Chemistry & Engineering 4 (3), 457-489, 2019
242019
Heterocycles in natural product synthesis
DL Riley, WAL van Otterlo, KC Majumdar, SK Chattopadhyay)
Majumdar, KC, Chattopadhyay, SK, Eds, 2011
212011
Synthesis and anticancer activity of N-9- and N-7- substituted 1,2,3 triazole analogues of 2,6-di-substituted purine
J Khazir, BA Mir, G Chashoo, L Pilcher, D Riley
Medicinal Chemistry Research 29, 33-45, 2020
202020
Formal synthesis of (5R, 8R, 8aS)-indolizidine 209I via enaminones incorporating weinreb amides
CB de Koning, JP Michael, DL Riley
Heterocycles 79 (1), 935-953, 2009
202009
Approaches for performing reductions under continuous-flow conditions
DL Riley, NC Neyt
Synthesis 50 (14), 2707-2720, 2018
192018
Design, synthesis, and anticancer evaluation of acetamide and hydrazine analogues of pyrimidine
J Khazir, BA Mir, G Chashoo, T Maqbool, D Riley, L Pilcher
Journal of Heterocyclic Chemistry 57 (3), 1306-1318, 2020
182020
An improved process for the preparation of tenofovir disoproxil fumarate
DL Riley, DR Walwyn, CD Edlin
Organic Process Research & Development 20 (4), 742-750, 2016
182016
Immobilized tetrakis (triphenylphosphine) palladium (0) for Suzuki–Miyaura coupling reactions under flow conditions
GV Ramaotsoa, I Strydom, JL Panayides, D Riley
Reaction Chemistry & Engineering 4 (2), 372-382, 2019
162019
Design, synthesis and anticancer activity of Michael-type thiol adducts of α-santonin analogue with exocyclic methylene
J Khazir, DL Riley, G Chashoo, BA Mir, D Liles, MA Islam, SK Singh, ...
European Journal of Medicinal Chemistry 101, 769-779, 2015
162015
An inquiry-based practical curriculum for organic chemistry as preparation for industry and postgraduate research
LA Pilcher, DL Riley, KC Mathabathe, M Potgieter
South African Journal of Chemistry 68, 236-244, 2015
162015
New syntheses of (±)-tashiromine and (±)-epitashiromine via enaminone intermediates
DL Riley, JP Michael, CB De Koning
Beilstein journal of organic chemistry 12 (1), 2609-2613, 2016
152016
Improved batch and flow syntheses of the nonsteroidal anti-inflammatory COX-2 inhibitor celecoxib
C Scholtz, DL Riley
Reaction Chemistry & Engineering 6 (1), 138-146, 2021
122021
A reaction energy profile and fragment attributed molecular system energy change (FAMSEC)-based protocol designed to uncover reaction mechanisms: A case study of the proline …
I Cukrowski, G Dhimba, DL Riley
Physical Chemistry Chemical Physics 21 (30), 16694-16705, 2019
122019
Discovery of novel acetylcholinesterase inhibitors by virtual screening, in vitro screening, and molecular dynamics simulations
CJ van der Westhuizen, A Stander, DL Riley, JL Panayides
Journal of Chemical Information and Modeling 62 (6), 1550-1572, 2022
112022
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