Role of plants in anticancer drug discovery J Khazir, BA Mir, L Pilcher, DL Riley Phytochemistry letters 7, 173-181, 2014 | 237 | 2014 |
Anticancer agents from diverse natural sources J Khazir, DL Riley, LA Pilcher, P De-Maayer, BA Mir Natural product communications 9 (11), 1934578X1400901130, 2014 | 104 | 2014 |
Targeting Alzheimer's disease by investigating previously unexplored chemical space surrounding the cholinesterase inhibitor donepezil DG van Greunen, W Cordier, M Nell, C van der Westhuyzen, ... European Journal of Medicinal Chemistry 127, 671-690, 2017 | 49 | 2017 |
Application of reactor engineering concepts in continuous flow chemistry: a review NC Neyt, DL Riley Reaction Chemistry & Engineering 6 (8), 1295-1326, 2021 | 44 | 2021 |
Novel N-benzylpiperidine carboxamide derivatives as potential cholinesterase inhibitors for the treatment of Alzheimer's disease DG van Greunen, CJ van der Westhuizen, W Cordier, M Nell, A Stander, ... European Journal of Medicinal Chemistry 179, 680-693, 2019 | 30 | 2019 |
Batch–flow hybrid synthesis of the antipsychotic clozapine NC Neyt, DL Riley Reaction Chemistry & Engineering 3 (1), 17-24, 2018 | 28 | 2018 |
Landscape and opportunities for active pharmaceutical ingredient manufacturing in developing African economies DL Riley, I Strydom, R Chikwamba, JL Panayides Reaction Chemistry & Engineering 4 (3), 457-489, 2019 | 24 | 2019 |
Heterocycles in natural product synthesis DL Riley, WAL van Otterlo, KC Majumdar, SK Chattopadhyay) Majumdar, KC, Chattopadhyay, SK, Eds, 2011 | 21 | 2011 |
Synthesis and anticancer activity of N-9- and N-7- substituted 1,2,3 triazole analogues of 2,6-di-substituted purine J Khazir, BA Mir, G Chashoo, L Pilcher, D Riley Medicinal Chemistry Research 29, 33-45, 2020 | 20 | 2020 |
Formal synthesis of (5R, 8R, 8aS)-indolizidine 209I via enaminones incorporating weinreb amides CB de Koning, JP Michael, DL Riley Heterocycles 79 (1), 935-953, 2009 | 20 | 2009 |
Approaches for performing reductions under continuous-flow conditions DL Riley, NC Neyt Synthesis 50 (14), 2707-2720, 2018 | 19 | 2018 |
Design, synthesis, and anticancer evaluation of acetamide and hydrazine analogues of pyrimidine J Khazir, BA Mir, G Chashoo, T Maqbool, D Riley, L Pilcher Journal of Heterocyclic Chemistry 57 (3), 1306-1318, 2020 | 18 | 2020 |
An improved process for the preparation of tenofovir disoproxil fumarate DL Riley, DR Walwyn, CD Edlin Organic Process Research & Development 20 (4), 742-750, 2016 | 18 | 2016 |
Immobilized tetrakis (triphenylphosphine) palladium (0) for Suzuki–Miyaura coupling reactions under flow conditions GV Ramaotsoa, I Strydom, JL Panayides, D Riley Reaction Chemistry & Engineering 4 (2), 372-382, 2019 | 16 | 2019 |
Design, synthesis and anticancer activity of Michael-type thiol adducts of α-santonin analogue with exocyclic methylene J Khazir, DL Riley, G Chashoo, BA Mir, D Liles, MA Islam, SK Singh, ... European Journal of Medicinal Chemistry 101, 769-779, 2015 | 16 | 2015 |
An inquiry-based practical curriculum for organic chemistry as preparation for industry and postgraduate research LA Pilcher, DL Riley, KC Mathabathe, M Potgieter South African Journal of Chemistry 68, 236-244, 2015 | 16 | 2015 |
New syntheses of (±)-tashiromine and (±)-epitashiromine via enaminone intermediates DL Riley, JP Michael, CB De Koning Beilstein journal of organic chemistry 12 (1), 2609-2613, 2016 | 15 | 2016 |
Improved batch and flow syntheses of the nonsteroidal anti-inflammatory COX-2 inhibitor celecoxib C Scholtz, DL Riley Reaction Chemistry & Engineering 6 (1), 138-146, 2021 | 12 | 2021 |
A reaction energy profile and fragment attributed molecular system energy change (FAMSEC)-based protocol designed to uncover reaction mechanisms: A case study of the proline … I Cukrowski, G Dhimba, DL Riley Physical Chemistry Chemical Physics 21 (30), 16694-16705, 2019 | 12 | 2019 |
Discovery of novel acetylcholinesterase inhibitors by virtual screening, in vitro screening, and molecular dynamics simulations CJ van der Westhuizen, A Stander, DL Riley, JL Panayides Journal of Chemical Information and Modeling 62 (6), 1550-1572, 2022 | 11 | 2022 |