| Cell-Cycle Reprogramming for PI3K Inhibition Overrides a Relapse-Specific C481S BTK Mutation Revealed by Longitudinal Functional Genomics in Mantle Cell … D Chiron, M Di Liberto, P Martin, X Huang, J Sharman, P Blecua, ... Cancer discovery 4 (9), 1022-1035, 2014 | 323* | 2014 |
| Toll-like receptors: lessons to learn from normal and malignant human B cells D Chiron, I Bekeredjian-Ding, C Pellat-Deceunynck, R Bataille, G Jego Blood, The Journal of the American Society of Hematology 112 (6), 2205-2213, 2008 | 164 | 2008 |
| Ibrutinib, obinutuzumab, and venetoclax in relapsed and untreated patients with mantle cell lymphoma: a phase 1/2 trial S Le Gouill, F Morschhauser, D Chiron, K Bouabdallah, G Cartron, ... Blood, The Journal of the American Society of Hematology 137 (7), 877-887, 2021 | 125* | 2021 |
| Rational targeted therapies to overcome microenvironment-dependent expansion of mantle cell lymphoma D Chiron, C Bellanger, A Papin, B Tessoulin, C Dousset, S Maiga, ... Blood, The Journal of the American Society of Hematology 128 (24), 2808-2818, 2016 | 96 | 2016 |
| Biological rational for sequential targeting of Bruton tyrosine kinase and Bcl-2 to overcome CD40-induced ABT-199 resistance in mantle cell lymphoma D Chiron, C Dousset, C Brosseau, C Touzeau, S Maïga, P Moreau, ... Oncotarget 6 (11), 8750, 2015 | 89 | 2015 |
| Induction of prolonged early G1 arrest by CDK4/CDK6 inhibition reprograms lymphoma cells for durable PI3Kδ inhibition through PIK3IP1 D Chiron, P Martin, M Di Liberto, X Huang, S Ely, BJ Lannutti, JP Leonard, ... Cell cycle 12 (12), 1892-1900, 2013 | 82 | 2013 |
| TLR3 ligand induces NF-κB activation and various fates of multiple myeloma cells depending on IFN-α production D Chiron, C Pellat-Deceunynck, M Amiot, R Bataille, G Jego The Journal of Immunology 182 (7), 4471-4478, 2009 | 79 | 2009 |
| Cell death via DR5, but not DR4, is regulated by p53 in myeloma cells S Surget, D Chiron, P Gomez-Bougie, G Descamps, E Ménoret, R Bataille, ... Cancer research 72 (17), 4562-4573, 2012 | 71 | 2012 |
| BCL2-family dysregulation in B-cell malignancies: from gene expression regulation to a targeted therapy biomarker B Tessoulin, A Papin, P Gomez-Bougie, C Bellanger, M Amiot, ... Frontiers in oncology 8, 645, 2019 | 69 | 2019 |
| CSF1R and BTK inhibitions as novel strategies to disrupt the dialog between mantle cell lymphoma and macrophages A Papin, B Tessoulin, C Bellanger, A Moreau, Y Le Bris, H Maisonneuve, ... Leukemia 33 (10), 2442-2453, 2019 | 56 | 2019 |
| p53 dysregulation in B-cell malignancies: More than a single gene in the pathway to hell B Tessoulin, M Eveillard, A Lok, D Chiron, P Moreau, M Amiot, ... Blood Reviews 31 (4), 251-259, 2017 | 56 | 2017 |
| Critical role of the NOTCH ligand JAG2 in self-renewal of myeloma cells D Chiron, S Maïga, G Descamps, P Moreau, S Le Gouill, S Marionneau, ... Blood Cells, Molecules, and Diseases 48 (4), 247-253, 2012 | 41 | 2012 |
| Whole-exon sequencing of human myeloma cell lines shows mutations related to myeloma patients at relapse with major hits in the DNA regulation and repair pathways B Tessoulin, A Moreau-Aubry, G Descamps, P Gomez-Bougie, S Maïga, ... Journal of hematology & oncology 11, 1-13, 2018 | 40 | 2018 |
| Phosphorothioate-modified TLR9 ligands protect cancer cells against TRAIL-induced apoptosis D Chiron, C Pellat-Deceunynck, M Maillasson, R Bataille, G Jego The Journal of Immunology 183 (7), 4371-4377, 2009 | 38 | 2009 |
| The peripheral CD138+ population but not the CD138− population contains myeloma clonogenic cells in plasma cell leukaemia patients. D Chiron, S Surget, S Maïga, R Bataille, P Moreau, S Le Gouill, M Amiot, ... British journal of haematology 156 (5), 2012 | 37 | 2012 |
| Pannexin‐1 limits the production of proinflammatory cytokines during necroptosis T Douanne, G André‐Grégoire, K Trillet, A Thys, A Papin, M Feyeux, ... EMBO reports 20 (10), e47840, 2019 | 35 | 2019 |
| Autocrine insulin-like growth factor 1 and stem cell factor but not interleukin 6 support self-renewal of human myeloma cells D Chiron, S Maiga, S Surget, G Descamps, P Gomez-Bougie, S Traore, ... Blood cancer journal 3 (6), e120-e120, 2013 | 35 | 2013 |
| Crosstalk between ROR1 and BCR pathways defines novel treatment strategies in mantle cell lymphoma H Karvonen, D Chiron, W Niininen, S Ek, M Jerkeman, E Moradi, M Nykter, ... Blood advances 1 (24), 2257-2268, 2017 | 34 | 2017 |
| TLR9 ligand induces the generation of CD20+ plasmablasts and plasma cells from CD27+ memory B-cells A Geffroy-Luseau, D Chiron, G Descamps, G Jégo, M Amiot, ... Frontiers in immunology 2, 83, 2011 | 34 | 2011 |
| Toll-like receptors: expression and involvement in multiple myeloma D Chiron, G Jego, C Pellat-Deuceunynck Leukemia research 34 (12), 1545-1550, 2010 | 30 | 2010 |
Catherine Pellat-DeceunynckCRCINA INSERM 1232 CNRS 6001在 inserm.fr 的电子邮件经过验证
