| Antisense therapeutics: is it as simple as complementary base recognition? S Agrawal, ER Kandimalla Molecular medicine today 6 (2), 72-81, 2000 | 395 | 2000 |
| Survivin inhibition induces human neural tumor cell death through caspase‐independent and‐dependent pathways SL Shankar, S Mani, KN O'Guin, ER Kandimalla, S Agrawal, ... Journal of neurochemistry 79 (2), 426-436, 2001 | 259 | 2001 |
| Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5′ ends S Agrawal, ER Kandimalla, D Yu, L Bhagat US Patent 7,276,489, 2007 | 231 | 2007 |
| Loss of XIAP protein expression by RNAi and antisense approaches sensitizes cancer cells to functionally diverse chemotherapeutics DC McManus, CA Lefebvre, G Cherton-Horvat, M St-Jean, ER Kandimalla, ... Oncogene 23 (49), 8105-8117, 2004 | 226 | 2004 |
| Immunomodulatory oligonucleotides containing a cytosine-phosphate-2′-deoxy-7-deazaguanosine motif as potent toll-like receptor 9 agonists ER Kandimalla, L Bhagat, Y Li, D Yu, D Wang, YP Cong, SS Song, ... Proceedings of the National Academy of Sciences 102 (19), 6925-6930, 2005 | 205 | 2005 |
| Preclinical characterization of AEG35156/GEM 640, a second-generation antisense oligonucleotide targeting X-linked inhibitor of apoptosis EC LaCasse, GG Cherton-Horvat, KE Hewitt, LJ Jerome, SJ Morris, ... Clinical cancer research 12 (17), 5231-5241, 2006 | 180 | 2006 |
| Inhibition of 14q32 MicroRNAs miR-329, miR-487b, miR-494, and miR-495 increases neovascularization and blood flow recovery after ischemia SMJ Welten, AJNM Bastiaansen, RCM de Jong, MR de Vries, EAB Peters, ... Circulation research 115 (8), 696-708, 2014 | 172 | 2014 |
| Synthetic agonists of Toll-like receptors 7, 8 and 9 S Agrawal, ER Kandimalla Biochemical Society Transactions 35 (6), 1461-1467, 2007 | 161 | 2007 |
| Divergent synthetic nucleotide motif recognition pattern: design and development of potent immunomodulatory oligodeoxyribonucleotide agents with distinct cytokine induction … ER Kandimalla, L Bhagat, D Wang, D Yu, FG Zhu, J Tang, H Wang, ... Nucleic Acids Research 31 (9), 2393-2400, 2003 | 152 | 2003 |
| Antisense and/or immunostimulatory oligonucleotide therapeutics S Agrawal, ER Kandimalla Current Cancer Drug Targets 1 (3), 197-209, 2001 | 132 | 2001 |
| Effect of chemical modifications of cytosine and guanine in a CpG-motif of oligonucleotides: structure–immunostimulatory activity relationships ER Kandimalla, D Yu, Q Zhao, S Agrawal Bioorganic & medicinal chemistry 9 (3), 807-813, 2001 | 132 | 2001 |
| Medicinal chemistry and therapeutic potential of CpG DNA S Agrawal, ER Kandimalla Trends in molecular medicine 8 (3), 114-121, 2002 | 131 | 2002 |
| Conjugation of ligands at the 5 ‘-end of CpG DNA affects immunostimulatory activity ER Kandimalla, L Bhagat, D Yu, Y Cong, J Tang, S Agrawal Bioconjugate chemistry 13 (5), 966-974, 2002 | 129 | 2002 |
| Design, synthesis and biological evaluation of novel antagonist compounds of Toll-like receptors 7, 8 and 9 ER Kandimalla, L Bhagat, D Wang, D Yu, T Sullivan, N La Monica, ... Nucleic acids research 41 (6), 3947-3961, 2013 | 128 | 2013 |
| Accessible 5′-end of CpG-containing phosphorothioate oligodeoxynucleotides is essential for immunostimulatory activity D Yu, Q Zhao, ER Kandimalla, S Agrawal Bioorganic & medicinal chemistry letters 10 (23), 2585-2588, 2000 | 124 | 2000 |
| Role of Toll-like receptors in antisense and siRNA [corrected]. S Agrawal, ER Kandimalla Nature biotechnology 22 (12), 1533-1537, 2004 | 123 | 2004 |
| Stereo-enriched phosphorothioate oligodeoxynucleotides: synthesis, biophysical and biological properties D Yu, ER Kandimalla, A Roskey, Q Zhao, L Chen, J Chen, S Agrawal Bioorganic & medicinal chemistry 8 (1), 275-284, 2000 | 122 | 2000 |
| ‘Immunomers’—novel 3′–3′‐linked CpG oligodeoxyribonucleotides as potent immunomodulatory agents D Yu, ER Kandimalla, L Bhagat, JY Tang, Y Cong, J Tang, S Agrawal Nucleic acids research 30 (20), 4460-4469, 2002 | 115 | 2002 |
| Mixed backbone antisense oligonucleotides containing 2'-5'-ribonucleotide-and 3'-5'-deoxyribonucleotides segments ER Kandimalla, S Agrawal US Patent 5,886,165, 1999 | 111 | 1999 |
| Antisense oligonucleotides targeting the epidermal growth factor receptor inhibit proliferation, induce apoptosis, and cooperate with cytotoxic drugs in human cancer cell lines F Ciardiello, R Caputo, T Troiani, G Borriello, ER Kandimalla, S Agrawal, ... International journal of cancer 93 (2), 172-178, 2001 | 108 | 2001 |
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