Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression NR Wray, S Ripke, M Mattheisen, M Trzaskowski, EM Byrne, A Abdellaoui, ... Nature genetics 50 (5), 668-681, 2018 | 2583 | 2018 |
Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions DM Howard, MJ Adams, TK Clarke, JD Hafferty, J Gibson, M Shirali, ... Nature neuroscience 22 (3), 343-352, 2019 | 1928 | 2019 |
Severe COVID-19 is marked by a dysregulated myeloid cell compartment J Schulte-Schrepping, N Reusch, D Paclik, K Baßler, S Schlickeiser, ... Cell 182 (6), 1419-1440. e23, 2020 | 1288 | 2020 |
A mutation in VPS35, encoding a subunit of the retromer complex, causes late-onset Parkinson disease A Zimprich, A Benet-Pagès, W Struhal, E Graf, SH Eck, MN Offman, ... The American Journal of Human Genetics 89 (1), 168-175, 2011 | 1069 | 2011 |
Genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders PH Lee, V Anttila, H Won, YCA Feng, J Rosenthal, Z Zhu, EM Tucker-Drob, ... Cell 179 (7), 1469-1482. e11, 2019 | 1061 | 2019 |
Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology N Mullins, AJ Forstner, KS O’Connell, B Coombes, JRI Coleman, Z Qiao, ... Nature genetics 53 (6), 817-829, 2021 | 809 | 2021 |
Mapping the human genetic architecture of COVID-19 Writing group Writing group leaders Pathak Gita A. 6 Andrews Shea J. 7 Kanai ... Nature 600 (7889), 472-477, 2021 | 741 | 2021 |
Swarm learning for decentralized and confidential clinical machine learning S Warnat-Herresthal, H Schultze, KL Shastry, S Manamohan, ... Nature 594 (7862), 265-270, 2021 | 588 | 2021 |
Longitudinal multi-omics analyses identify responses of megakaryocytes, erythroid cells, and plasmablasts as hallmarks of severe COVID-19 JP Bernardes, N Mishra, F Tran, T Bahmer, L Best, JI Blase, D Bordoni, ... Immunity 53 (6), 1296-1314. e9, 2020 | 303 | 2020 |
Minimal phenotyping yields genome-wide association signals of low specificity for major depression N Cai, JA Revez, MJ Adams, TFM Andlauer, G Breen, EM Byrne, ... Nature genetics 52 (4), 437-447, 2020 | 247 | 2020 |
Disease severity-specific neutrophil signatures in blood transcriptomes stratify COVID-19 patients AC Aschenbrenner, M Mouktaroudi, B Krämer, M Oestreich, N Antonakos, ... Genome medicine 13, 1-25, 2021 | 236 | 2021 |
Genome-wide association study identifies novel restless legs syndrome susceptibility loci on 2p14 and 16q12. 1 J Winkelmann, D Czamara, B Schormair, F Knauf, EC Schulte, ... PLoS genetics 7 (7), e1002171, 2011 | 215 | 2011 |
Genetic association of major depression with atypical features and obesity-related immunometabolic dysregulations Y Milaneschi, F Lamers, WJ Peyrot, BT Baune, G Breen, A Dehghan, ... JAMA psychiatry 74 (12), 1214-1225, 2017 | 182 | 2017 |
Early IFN-α signatures and persistent dysfunction are distinguishing features of NK cells in severe COVID-19 B Krämer, R Knoll, L Bonaguro, M ToVinh, J Raabe, ... Immunity 54 (11), 2650-2669. e14, 2021 | 178 | 2021 |
Cerebral venous thrombosis and severe acute respiratory syndrome coronavirus‐2 infection: a systematic review and meta‐analysis T Baldini, GM Asioli, M Romoli, M Carvalho Dias, EC Schulte, L Hauer, ... European journal of neurology 28 (10), 3478-3490, 2021 | 169 | 2021 |
Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank JRI Coleman, WJ Peyrot, KL Purves, KAS Davis, C Rayner, SW Choi, ... Molecular psychiatry 25 (7), 1430-1446, 2020 | 153 | 2020 |
The genetics of the mood disorder spectrum: genome-wide association analyses of more than 185,000 cases and 439,000 controls JRI Coleman, HA Gaspar, J Bryois, EM Byrne, AJ Forstner, PA Holmans, ... Biological psychiatry 88 (2), 169-184, 2020 | 146 | 2020 |
Dissecting the shared genetic architecture of suicide attempt, psychiatric disorders, and known risk factors N Mullins, JE Kang, AI Campos, JRI Coleman, AC Edwards, H Galfalvy, ... Biological psychiatry 91 (3), 313-327, 2022 | 145 | 2022 |
A comparison of ten polygenic score methods for psychiatric disorders applied across multiple cohorts G Ni, J Zeng, JA Revez, Y Wang, Z Zheng, T Ge, R Restuadi, J Kiewa, ... Biological psychiatry 90 (9), 611-620, 2021 | 139 | 2021 |
The genetic basis of major depression KM Kendall, E Van Assche, TFM Andlauer, KW Choi, JJ Luykx, ... Psychological Medicine 51 (13), 2217-2230, 2021 | 119 | 2021 |