Engineering of TEV protease variants by yeast ER sequestration screening (YESS) of combinatorial libraries L Yi, MC Gebhard, Q Li, JM Taft, G Georgiou, BL Iverson Proceedings of the National Academy of Sciences 110 (18), 7229-7234, 2013 | 158 | 2013 |
Deep mutational learning predicts ACE2 binding and antibody escape to combinatorial mutations in the SARS-CoV-2 receptor-binding domain JM Taft, CR Weber, B Gao, RA Ehling, J Han, L Frei, SW Metcalfe, ... Cell 185 (21), 4008-4022. e14, 2022 | 72 | 2022 |
Recombinant antibodies to histone post-translational modifications T Hattori, JM Taft, KM Swist, H Luo, H Witt, M Slattery, A Koide, ... Nature methods 10 (10), 992-995, 2013 | 72 | 2013 |
Driving CARs with alternative navigation tools–the potential of engineered binding scaffolds CU Zajc, B Salzer, JM Taft, ST Reddy, M Lehner, MW Traxlmayr The FEBS journal 288 (7), 2103-2118, 2021 | 30 | 2021 |
Yeast endoplasmic reticulum sequestration screening for the engineering of proteases from libraries expressed in yeast L Yi, JM Taft, Q Li, MC Gebhard, G Georgiou, BL Iverson Yeast Surface Display: Methods, Protocols, and Applications, 81-93, 2015 | 13 | 2015 |
Rapid screen for tyrosine kinase inhibitor resistance mutations and substrate specificity JM Taft, S Georgeon, C Allen, S Reckel, J DeSautelle, O Hantschel, ... ACS chemical biology 14 (9), 1888-1895, 2019 | 11 | 2019 |
The physiological landscape and specificity of antibody repertoires L Csepregi, KB Hoehn, D Neumeier, JM Taft, S Friedensohn, CR Weber, ... bioRxiv, 2021.09. 15.460420, 2021 | 6 | 2021 |
Method for engineering proteases and protein kinases BL Iverson, G Georgiou, L Yi US Patent 8,945,855, 2015 | 4 | 2015 |
A synthetic bispecific antibody capable of neutralizing SARS-CoV-2 Delta and Omicron TZ Yuan, C Lucas, VS Monteiro, A Iwasaki, ML Yang, HF Nepita, ... bioRxiv, 2022.01. 04.474803, 2022 | 3 | 2022 |
Methods for generating engineered enzymes B Iverson, P Marek, T Joseph US Patent 10,900,059, 2021 | 3 | 2021 |
Deep learning-guided selection of antibody therapies with enhanced resistance to current and prospective SARS-CoV-2 Omicron variants L Frei, B Gao, J Han, JM Taft, EB Irvine, CR Weber, R Kumar, B Eisinger, ... bioRxiv, 2023.10. 09.561492, 2023 | 2 | 2023 |
Synthetic coevolution reveals adaptive mutational trajectories of neutralizing antibodies and SARS-CoV-2 RA Ehling, M Minot, MD Overath, DJ Sheward, J Han, B Gao, JM Taft, ... bioRxiv, 2024.03. 28.587189, 2024 | 1 | 2024 |
Methods for predicting kinase inhibitor resistance B Iverson, G Georgiou, J Desautelle, T Joseph US Patent 11,236,380, 2022 | 1 | 2022 |
Methods for predicting kinase inhibitor resistance B Iverson, G Georgiou, J Desautelle, T Joseph US Patent App. 17/567,868, 2022 | | 2022 |
Compositions and methods related to recombinant antibodies to histone posttranslational modifications T Hattori, S Koide, T Joseph, A Koide | | 2014 |