Cathelicidin promotes inflammation by enabling binding of self-RNA to cell surface scavenger receptors T Takahashi, NN Kulkarni, EY Lee, L Zhang, GCL Wong, RL Gallo Scientific reports 8 (1), 4032, 2018 | 78 | 2018 |
Phenylbutyrate induces cathelicidin expression via the vitamin D receptor: Linkage to inflammatory and growth factor cytokines pathways NN Kulkarni, Z Yi, C Huehnken, B Agerberth, GH Gudmundsson Molecular immunology 63 (2), 530-539, 2015 | 62 | 2015 |
Innate immune dysfunction in rosacea promotes photosensitivity and vascular adhesion molecule expression NN Kulkarni, T Takahashi, JA Sanford, Y Tong, AF Gombart, B Hinds, ... Journal of Investigative Dermatology 140 (3), 645-655. e6, 2020 | 46 | 2020 |
Bordetella pertussis adenylate cyclase toxin disrupts functional integrity of bronchial epithelial layers S Hasan, NN Kulkarni, A Asbjarnarson, I Linhartova, R Osicka, P Sebo, ... Infection and immunity 86 (3), 10.1128/iai. 00445-17, 2018 | 44 | 2018 |
Cutaneous innate immune tolerance is mediated by epigenetic control of MAP2K3 by HDAC8/9 Y Sawada, T Nakatsuji, T Dokoshi, NN Kulkarni, MC Liggins, G Sen, ... Science immunology 6 (59), eabe1935, 2021 | 38 | 2021 |
Glucocorticoid dexamethasone down-regulates basal and vitamin D3 induced cathelicidin expression in human monocytes and bronchial epithelial cell line NN Kulkarni, HI Gunnarsson, Z Yi, S Gudmundsdottir, OE Sigurjonsson, ... Immunobiology 221 (2), 245-252, 2016 | 28 | 2016 |
Viral afterlife: SARS-CoV-2 as a reservoir of immunomimetic peptides that reassemble into proinflammatory supramolecular complexes Y Zhang, V Bharathi, T Dokoshi, J de Anda, LT Ursery, NN Kulkarni, ... Proceedings of the National Academy of Sciences 121 (6), e2300644120, 2024 | 19 | 2024 |
IL-1 receptor–knockout mice develop epidermal cysts and show an altered innate immune response after exposure to UVB radiation NN Kulkarni, CA Adase, L Zhang, AW Borkowski, F Li, JA Sanford, ... Journal of Investigative Dermatology 137 (11), 2417-2426, 2017 | 18 | 2017 |
Cyclic mechanical stretch down-regulates cathelicidin antimicrobial peptide expression and activates a pro-inflammatory response in human bronchial epithelial cells H Karadottir, NN Kulkarni, T Gudjonsson, S Karason, GH Gudmundsson PeerJ 3, e1483, 2015 | 18 | 2015 |
Antimicrobials from a feline commensal bacterium inhibit skin infection by drug-resistant S. pseudintermedius AM O'Neill, KA Worthing, N Kulkarni, F Li, T Nakatsuji, D McGrosso, ... Elife 10, e66793, 2021 | 16 | 2021 |
Sequence determinants in the cathelicidin LL-37 that promote inflammation via presentation of RNA to scavenger receptors NN Kulkarni, AM O’Neill, T Dokoshi, EWC Luo, GCL Wong, RL Gallo Journal of Biological Chemistry 297 (1), 2021 | 11 | 2021 |
Increased LL37 in psoriasis and other inflammatory disorders promotes LDL uptake and atherosclerosis Y Nakamura, NN Kulkarni, T Takahashi, H Alimohamadi, T Dokoshi, E Liu, ... The Journal of clinical investigation 134 (5), 2024 | 3 | 2024 |
3D genomic features across> 50 diverse cell types reveal insights into the genomic architecture of childhood obesity KB Trang, MC Pahl, JA Pippin, C Su, SH Littleton, P Sharma, NN Kulkarni, ... medRxiv, 2024 | 1 | 2024 |
886 Discovery of a receptor-dependent step in cathelicidin activation of inflammation identifies a novel therapeutic target for psoriasis and rosacea T Takahashi, NN Kulkarni, EY Lee, L Zhang, GCL Wong, S Aiba, RL Gallo Journal of Investigative Dermatology 138 (5), S151, 2018 | 1 | 2018 |
531 Cardiovascular comorbidities are associated with increased LL37 which promotes the uptake of low-density lipoprotein into macrophages RG Y Nakamura, Nikhil K, T Dokoshi, E Luo, G Wong Journal of Investigative Dermatology 142 (8 Supplement), S90, 2022 | | 2022 |
207 Targeting of HDAC8 and HDAC9 in keratinocytes to enhance skin immune defense Y Sawada, T Dokoshi, N Kulkarni, M Liggins, T Nakatsuji, G Sen, R Gallo Journal of Investigative Dermatology 141 (5), S37, 2021 | | 2021 |
337 Innate immune tolerance of the epidermis is mediated by epigenetic regulation of MAP2K3 Y Sawada, T Nakatsuji, T Dokoshi, N Kulkarni, J Jones, G Sen, M Liggins, ... Journal of Investigative Dermatology 140 (7), S42, 2020 | | 2020 |
LL-37 promotes endothelial photo-sensitivity and adhesion molecule expression in Rosacea NN Kulkarni, T Takahashi, L Tong, JY Cheng, RL Gallo Journal of Investigative Dermatology 139 (5), S126-S126, 2019 | | 2019 |
1170 LL-37 acts on dermal microvascular endothelial cells to potentiate non-coding double strandedds RNA induced inflammation. An explanation for photosensitivity in Rosacea NN Kulkarni, C Adase, RL Gallo Journal of Investigative Dermatology 138 (5), S199, 2018 | | 2018 |
Cyclic stretch and expression of innate immune effectors in lung epithelial cell lines H Karadottir, NN Kulkarni, T Gudjonsson, GH Gudmundsson, S Karason ACTA ANAESTHESIOLOGICA SCANDINAVICA 59, 30-30, 2015 | | 2015 |