Toll‐like receptors: the swiss army knife of immunity and vaccine development JK Dowling, A Mansell Clinical & translational immunology 5 (5), e85, 2016 | 328 | 2016 |
Reassessing the role of the NLRP3 inflammasome during pathogenic influenza A virus infection via temporal inhibition MD Tate, JDH Ong, JK Dowling, JL McAuley, AB Robertson, E Latz, ... Scientific reports 6 (1), 27912, 2016 | 205 | 2016 |
A Role for TLR4 in Clostridium difficile Infection and the Recognition of Surface Layer Proteins A Ryan, M Lynch, SM Smith, S Amu, HJ Nel, CE McCoy, JK Dowling, ... PLoS pathogens 7 (6), e1002076, 2011 | 198 | 2011 |
Inflammasome activity is essential for one kidney/deoxycorticosterone acetate/salt‐induced hypertension in mice SM Krishnan, JK Dowling, YH Ling, H Diep, CT Chan, D Ferens, MM Kett, ... British journal of pharmacology 173 (4), 752-765, 2016 | 184 | 2016 |
Biochemical regulation of the inflammasome JK Dowling, LAJ O’Neill Critical reviews in biochemistry and molecular biology 47 (5), 424-443, 2012 | 165 | 2012 |
Mitochondrial arginase-2 is essential for IL-10 metabolic reprogramming of inflammatory macrophages JK Dowling, R Afzal, LJ Gearing, MP Cervantes-Silva, S Annett, GM Davis, ... Nature communications 12 (1), 1460, 2021 | 95 | 2021 |
PB1-F2 peptide derived from avian influenza A virus H7N9 induces inflammation via activation of the NLRP3 inflammasome A Pinar, JK Dowling, NJ Bitto, AAB Robertson, E Latz, CR Stewart, ... Journal of Biological Chemistry 292 (3), 826-836, 2017 | 90 | 2017 |
Membrane vesicles from Pseudomonas aeruginosa activate the noncanonical inflammasome through caspase‐5 in human monocytes NJ Bitto, PJ Baker, JK Dowling, G Wray‐McCann, A De Paoli, LS Tran, ... Immunology and Cell Biology 96 (10), 1120-1130, 2018 | 76 | 2018 |
Regulation of thromboxane receptor trafficking through the prostacyclin receptor in vascular smooth muscle cells: role of receptor heterodimerization SJ Wilson, JK Dowling, L Zhao, E Carnish, EM Smyth Arteriosclerosis, thrombosis, and vascular biology 27 (2), 290-296, 2007 | 57 | 2007 |
Toll-like receptors: ligands, cell-based models, and readouts for receptor action JK Dowling, J Dellacasagrande Toll-like receptors: practice and methods, 3-27, 2016 | 33 | 2016 |
Parsing the IL-37-mediated suppression of inflammasome function I Rudloff, HK Ung, JK Dowling, A Mansell, L D’Andrea, AM Ellisdon, ... Cells 9 (1), 178, 2020 | 26 | 2020 |
Impact of exercise on immunometabolism in multiple sclerosis R Afzal, JK Dowling, CE McCoy Journal of Clinical Medicine 9 (9), 3038, 2020 | 24 | 2020 |
Mycobacterial PIMs inhibit host inflammatory responses through CD14-dependent and CD14-independent mechanisms N Court, S Rose, ML Bourigault, S Front, OR Martin, JK Dowling, ... PLoS One 6 (9), e24631, 2011 | 23 | 2011 |
Multi-factorial nerve guidance conduit engineering improves outcomes in inflammation, angiogenesis and large defect nerve repair AJ Hibbitts, Z Kočí, S Kneafsey, A Matsiko, L Žilić, A Dervan, P Hinton, ... Matrix Biology 106, 34-57, 2022 | 19 | 2022 |
Biomaterial and therapeutic approaches for the manipulation of macrophage phenotype in peripheral and central nerve repair A Dervan, A Franchi, FR Almeida-Gonzalez, JK Dowling, OB Kwakyi, ... Pharmaceutics 13 (12), 2161, 2021 | 18 | 2021 |
Activation of liver X receptor suppresses the production of the IL-12 family of cytokines by blocking nuclear translocation of NF-κBp50 M Canavan, C McCarthy, NB Larbi, JK Dowling, L Collins, F O’Sullivan, ... Innate immunity 20 (7), 675-687, 2014 | 18 | 2014 |
Promyelocytic leukemia protein interacts with the apoptosis-associated speck-like protein to limit inflammasome activation JK Dowling, CE Becker, NM Bourke, SC Corr, DJ Connolly, SR Quinn, ... Journal of Biological Chemistry 289 (10), 6429-6437, 2014 | 18 | 2014 |
Conjugated linoleic acid suppresses IRF3 activation via modulation of CD14 JK Dowling, CE McCoy, SL Doyle, N BenLarbi, M Canavan, LA O'Neill, ... The Journal of Nutritional Biochemistry 24 (5), 920-928, 2013 | 14 | 2013 |
Novel mineralocorticoid receptor mechanisms regulate cardiac tissue inflammation in male mice GSY Ong, TJ Cole, GH Tesch, J Morgan, JK Dowling, A Mansell, PJ Fuller, ... Journal of Endocrinology 246 (2), 123-134, 2020 | 8 | 2020 |
The immunophilin protein FKBPL and its peptide derivatives are novel regulators of vascular integrity and inflammation via NF-κB signaling S Annett, S Spence, C Garciarena, C Campbell, M Dennehy, C Drakeford, ... bioRxiv, 2021.02. 24.431422, 2021 | 7 | 2021 |