Role of metal ion in specific recognition of pyrophosphate ion under physiological conditions and hydrolysis of the phosphoester linkage by alkaline phosphatase P Das, NB Chandar, S Chourey, H Agarwalla, B Ganguly, A Das Inorganic Chemistry 52 (19), 11034-11041, 2013 | 62 | 2013 |
Inhibition of 5-oxo-6, 8, 11, 14-eicosatetraenoic acid-induced activation of neutrophils and eosinophils by novel indole OXE receptor antagonists V Gore, S Gravel, C Cossette, P Patel, S Chourey, Q Ye, J Rokach, ... Journal of medicinal chemistry 57 (2), 364-377, 2014 | 32 | 2014 |
Two potent OXE-R antagonists: assignment of stereochemistry P Patel, CN Reddy, V Gore, S Chourey, Q Ye, YP Ouedraogo, S Gravel, ... ACS Medicinal Chemistry Letters 5 (7), 815-819, 2014 | 18 | 2014 |
Pharmacokinetics and metabolism of selective oxoeicosanoid (OXE) receptor antagonists and their effects on 5-oxo-6, 8, 11, 14-eicosatetraenoic acid (5-oxo-ETE)-induced … C Cossette, S Chourey, Q Ye, C Nagendra Reddy, V Gore, S Gravel, ... Journal of Medicinal Chemistry 59 (22), 10127-10146, 2016 | 16 | 2016 |
Biosynthesis and actions of 5-oxoeicosatetraenoic acid (5-oxo-ETE) on feline granulocytes C Cossette, S Gravel, CN Reddy, V Gore, S Chourey, Q Ye, NW Snyder, ... Biochemical pharmacology 96 (3), 247-255, 2015 | 15 | 2015 |
Stereoselective synthesis of two highly potent 5-oxo-ETE receptor antagonists CN Reddy, Q Ye, S Chourey, S Gravel, WS Powell, J Rokach Tetrahedron letters 56 (49), 6896-6899, 2015 | 14 | 2015 |
Novel highly potent OXE receptor antagonists with prolonged plasma lifetimes that are converted to active metabolites in vivo in monkeys Q Ye, S Chourey, CN Reddy, R Wang, C Cossette, S Gravel, ... British Journal of Pharmacology 177 (2), 388-401, 2020 | 11 | 2020 |
Inhibition of allergen‐induced dermal eosinophilia by an oxoeicosanoid receptor antagonist in non‐human primates LA Miller, C Cossette, S Chourey, Q Ye, CN Reddy, J Rokach, WS Powell British Journal of Pharmacology 177 (2), 360-371, 2020 | 10 | 2020 |
In vivo α-hydroxylation of a 2-alkylindole antagonist of the OXE receptor for the eosinophil chemoattractant 5-oxo-6, 8, 11, 14-eicosatetraenoic acid in monkeys S Chourey, Q Ye, CN Reddy, C Cossette, S Gravel, M Zeller, ... Biochemical pharmacology 138, 107-118, 2017 | 10 | 2017 |
Novel highly potent and metabolically resistant oxoeicosanoid (OXE) receptor antagonists that block the actions of the granulocyte chemoattractant 5-oxo-6, 8, 11, 14 … S Chourey, Q Ye, CN Reddy, R Wang, C Cossette, S Gravel, ... Journal of Medicinal Chemistry 61 (14), 5934-5948, 2018 | 9 | 2018 |
Stereoselective Synthesis of Maresin-like Lipid Mediators S Hong, Y Lu, M Morita, S Saito, Y Kobayashi, B Jun, NG Bazan, X Xu, ... Synlett 30 (03), 343-347, 2019 | 8 | 2019 |
Metabolism and pharmacokinetics of a potent N-acylindole antagonist of the OXE receptor for the eosinophil chemoattractant 5-oxo-6, 8, 11, 14-eicosatetraenoic acid (5-oxo-ETE … CN Reddy, H Alhamza, S Chourey, Q Ye, V Gore, C Cossette, S Gravel, ... European Journal of Pharmaceutical Sciences 115, 88-99, 2018 | 8 | 2018 |
Targeting the OXE receptor with a selective antagonist inhibits allergen‐induced pulmonary inflammation in non‐human primates C Cossette, LA Miller, Q Ye, S Chourey, CN Reddy, J Rokach, WS Powell British journal of pharmacology 179 (2), 322-336, 2022 | 7 | 2022 |
Structure-activity relationship study of β-oxidation resistant indole-based 5-oxo-6, 8, 11, 14-eicosatetraenoic acid (5-oxo-ETE) receptor antagonists Q Ye, S Chourey, R Wang, NR Chintam, S Gravel, WS Powell, J Rokach Bioorganic & medicinal chemistry letters 27 (20), 4770-4776, 2017 | 7 | 2017 |
Design and synthesis of affinity chromatography ligands for the purification of 5-hydroxyeicosanoid dehydrogenase CN Reddy, Q Ye, P Patel, S Sivendran, S Chourey, R Wang, JR Anumolu, ... Bioorganic & Medicinal Chemistry 25 (1), 116-125, 2017 | 7 | 2017 |
Base-dependent formation of cis and trans olefins and their application in the synthesis of 5-oxo-ETE receptor antagonists V Gore, S Chourey, Q Ye, P Patel, Y Ouedraogo, S Gravel, WS Powell, ... Bioorganic & Medicinal Chemistry Letters 24 (15), 3385-3388, 2014 | 6 | 2014 |
Metabolism of anti-inflammatory OXE (oxoeicosanoid) receptor antagonists by nonhuman primates C Cossette, S Chourey, Q Ye, CN Reddy, R Wang, S Poulet, ... European Journal of Pharmaceutical Sciences 172, 106144, 2022 | 1 | 2022 |
Concise Syntheses of Microsomal Metabolites of a Potent OXE (Oxoeicosanoid) Receptor Antagonist S Chourey, R Wang, Q Ye, CN Reddy, S Sun, N Takenaka, WS Powell, ... Chemical and Pharmaceutical Bulletin 71 (7), 534-544, 2023 | | 2023 |
Corrigendum to" In vivo α-hydroxylation of a 2-alkylindole antagonist of the OXE receptor for the eosinophil chemoattractant 5-oxo-6, 8, 11, 14-eicosatetraenoic acid in monkeys … S Chourey, Q Ye, CN Reddy, C Cossette, S Gravel, M Zeller, ... Biochemical pharmacology 154, 174, 2018 | | 2018 |
Structural modifications of OXE receptor antagonists towards improved in vivo metabolic stability S Chourey, Q Ye, C Reddy, R Wang, S Gravel, C Cossette, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 253, 2017 | | 2017 |