Lipid availability determines fate of skeletal progenitor cells via SOX9 N Van Gastel, S Stegen, G Eelen, S Schoors, A Carlier, VW Daniëls, ... Nature 579 (7797), 111-117, 2020 | 186 | 2020 |
Induction of a timed metabolic collapse to overcome cancer chemoresistance N Van Gastel, JB Spinelli, A Sharda, A Schajnovitz, N Baryawno, C Rhee, ... Cell Metabolism 32 (3), 391-403. e6, 2020 | 119 | 2020 |
An injectable bone marrow–like scaffold enhances T cell immunity after hematopoietic stem cell transplantation NJ Shah, AS Mao, TY Shih, MD Kerr, A Sharda, TM Raimondo, ... Nature biotechnology 37 (3), 293-302, 2019 | 106 | 2019 |
A biomaterial-based vaccine eliciting durable tumour-specific responses against acute myeloid leukaemia NJ Shah, AJ Najibi, TY Shih, AS Mao, A Sharda, DT Scadden, DJ Mooney Nature Biomedical Engineering 4 (1), 40-51, 2020 | 94 | 2020 |
Aldehyde dehydrogenase 3a2 protects AML cells from oxidative death and the synthetic lethality of ferroptosis inducers RZ Yusuf, B Saez, A Sharda, N Van Gastel, VWC Yu, N Baryawno, ... Blood, The Journal of the American Society of Hematology 136 (11), 1303-1316, 2020 | 88 | 2020 |
Malic enzyme 2 connects the Krebs cycle intermediate fumarate to mitochondrial biogenesis YP Wang, A Sharda, SN Xu, N Van Gastel, CH Man, U Choi, WZ Leong, ... Cell metabolism 33 (5), 1027-1041. e8, 2021 | 52 | 2021 |
A purinergic P2Y6 receptor agonist prodrug modulates airway inflammation, remodeling, and hyperreactivity in a mouse model of asthma A Chetty, A Sharda, R Warburton, EO Weinberg, J Dong, M Fang, ... Journal of asthma and allergy, 159-171, 2018 | 23 | 2018 |
PPM1D modulates hematopoietic cell fitness and response to DNA damage and is a therapeutic target in myeloid malignancy PG Miller, AS Sperling, C Mayerhofer, ME McConkey, JM Ellegast, ... Blood 142 (24), 2079-2091, 2023 | 16 | 2023 |
Untargeted metabolomics identifies glutamine metabolism as a driver of chemoresistance in acute myeloid Leukemia N van Gastel, A Schajnovitz, C Vidoudez, T Oki, A Sharda, SA Trauger, ... Blood 130, 2523, 2017 | 3 | 2017 |
IgE mediates broncho-vascular remodeling after neonatal sensitization in mice A Chetty, G Cao, A Sharda, T Tsay, HC Nielsen Frontiers in bioscience (Elite edition) 8, 370, 2016 | 2 | 2016 |
Cap-Independent Protein Translation in Hematopoiesis M Mazzola, T Zhao, K Gustafsson, T Kristiansen, G Schiroli, J Milosevic, ... Blood 140 (Supplement 1), 1983-1984, 2022 | 1 | 2022 |
Abstract PO085: Cryogel-based cancer vaccine to treat acute myeloid leukemia AJ Najibi, NJ Shah, TY Shih, AS Mao, A Sharda, DT Scadden, DJ Mooney Cancer Immunology Research 9 (2_Supplement), PO085-PO085, 2021 | 1 | 2021 |
The Distinctive Metabolic Environment of the Bone Marrow Niche Drives Leukemia Chemoresistance N van Gastel, JB Spinelli, A Sharda, A Schajnovitz, N Baryawno, CS Rhee, ... Blood 134, 3725, 2019 | 1 | 2019 |
Effect of a purinergic P2Y6 receptor agonist on airway remodeling and responsiveness in a mouse model of asthma A Chetty, A Sharda, R Warburton, T Chen, C Xue, J Castellot, PG Haydon, ... A64. TRANSLATIONAL RESEARCH IN PEDIATRIC ASTHMA, A2173-A2173, 2016 | 1 | 2016 |
3004–ACUTE MYELOID LEUKEMIA CELLS REQUIRE 18-CARBON LONG FATTY ACIDS FOR PROTEIN S-ACYLATION TO MAINTAIN MITOCHONDRIAL ACTIVITY AND METABOLIC PLASTICITY N van Gastel, N Balasundaram, A Erdem, A Sharda, V Daniels, P Chea, ... Experimental Hematology 137, 104292, 2024 | | 2024 |
Aldh3a2 inhibition and ferroptosis induction for cancer therapy DT Scadden, R Yusuf, N Van Gastel, AS Sharda, B Saez, ... US Patent App. 17/783,573, 2023 | | 2023 |
Author Correction: An injectable bone marrow-like scaffold enhances T cell immunity after hematopoietic stem cell transplantation NJ Shah, AS Mao, TY Shih, MD Kerr, A Sharda, TM Raimondo, ... Nature biotechnology 39 (11), 1466, 2021 | | 2021 |
Metabolic crosstalk in the bone marrow niche drives leukemia chemoresistance N van Gastel, A Schajnovitz, A Sharda, K Kokkaliaris, N Baryawno, ... JOURNAL OF BONE AND MINERAL RESEARCH 34, 132-133, 2019 | | 2019 |
System and Method to Generate Progenitor Cells BC Isenberg, JR Coppeta, RA Dubay, DT Scadden, AS Sharda US Patent App. 16/419,891, 2019 | | 2019 |
Platelet Delta Granule Evaluation in Lung Transplant Recipients with HPS-1 to Study Platelet Biogenesis DJ Appell, D Chen, K O'Brien, A Sharda, W Gahl, V Friedman, ... A43. ILD SCIENTIFIC ABSTRACTS: GENERAL, A1693-A1693, 2018 | | 2018 |