| Mitochondria-derived ROS activate AMP-activated protein kinase (AMPK) indirectly EC Hinchy, AV Gruszczyk, R Willows, N Navaratnam, AR Hall, G Bates, ... Journal of Biological Chemistry 293 (44), 17208-17217, 2018 | 260 | 2018 |
| Malonylation of GAPDH is an inflammatory signal in macrophages S Galván-Peña, RG Carroll, C Newman, EC Hinchy, ... Nature communications 10 (1), 338, 2019 | 161 | 2019 |
| Succinate accumulation drives ischaemia-reperfusion injury during organ transplantation JL Martin, ASH Costa, AV Gruszczyk, TE Beach, FM Allen, HA Prag, ... Nature metabolism 1 (10), 966-974, 2019 | 121 | 2019 |
| A helminth-derived suppressor of ST2 blocks allergic responses F Vacca, C Chauche, A Jamwal, EC Hinchy, G Heieis, H Webster, ... Elife 9, e54017, 2020 | 45 | 2020 |
| Selective disruption of mitochondrial thiol redox state in cells and in vivo LM Booty, JM Gawel, F Cvetko, ST Caldwell, AR Hall, JF Mulvey, ... Cell chemical biology 26 (3), 449-461. e8, 2019 | 43 | 2019 |
| Ventriculo‐arterial coupling detects occult RV dysfunction in chronic thromboembolic pulmonary vascular disease RG Axell, SJ Messer, PA White, C McCabe, A Priest, T Statopoulou, ... Physiological reports 5 (7), e13227, 2017 | 43 | 2017 |
| Selective mitochondrial superoxide generation in vivo is cardioprotective through hormesis S Antonucci, JF Mulvey, N Burger, M Di Sante, AR Hall, EC Hinchy, ... Free Radical Biology and Medicine 134, 678-687, 2019 | 41 | 2019 |
| Click-PEGylation–a mobility shift approach to assess the redox state of cysteines in candidate proteins LAG van Leeuwen, EC Hinchy, MP Murphy, EL Robb, HM Cochemé Free Radical Biology and Medicine 108, 374-382, 2017 | 39 | 2017 |
| Tozorakimab (MEDI3506): an anti-IL-33 antibody that inhibits IL-33 signalling via ST2 and RAGE/EGFR to reduce inflammation and epithelial dysfunction E England, DG Rees, IC Scott, S Carmen, DTY Chan, ... Scientific Reports 13 (1), 9825, 2023 | 28 | 2023 |
| APOPT 1/COA 8 assists COX assembly and is oppositely regulated by UPS and ROS A Signes, R Cerutti, AS Dickson, C Benincá, EC Hinchy, D Ghezzi, ... EMBO molecular medicine 11 (1), e9582, 2019 | 21 | 2019 |
| Tozorakimab: a dual-pharmacology anti-IL-33 antibody that inhibits IL-33 signalling via ST2 and RAGE/EGFR to reduce inflammation and epithelial dysfunction IC Scott, E England, DG Rees, T Erngren, CC Huntington, KF Houslay, ... European Respiratory Journal 60 (suppl 66), 2022 | 8 | 2022 |
| Tozorakimab (MEDI3506): a dual-pharmacology anti-IL-33 antibody that inhibits IL-33 signalling via ST2 and RAGE/EGFR to reduce inflammation and epithelial dysfunction E England, DG Rees, IC Scott, S Carmen, DTY Chan, ... bioRxiv, 2023.02. 28.527262, 2023 | 2 | 2023 |
| Distinct Pharmacological Profiles of IL-33 Antibodies S Cohen, S Strickson, IC Scott, A Collinson, G Rees, CC Huntington, ... B32. BIOMARKERS AND TRANSLATIONAL STUDIES IN COPD AND CHRONIC AIRWAYS …, 2024 | | 2024 |
| Succinate accumulation during organ storage drives ischemia-reperfusion injury upon transplantation JL Martin, ASH Costa, A Gruszczyk, T Beach, F Allen, H Prag, EC Hinchy, ... University of Glasgow, 2018 | | 2018 |
| SUCCINATE ACCUMULATION IS THE KEY METABOLOMIC SIGNATURE AND THERAPEUTIC TARGET FOR TRANSPLANT ISCHAEMIA-REPERFUSION INJURY IN MOUSE, PIG AND MAN J Martin, ASH Costa, A Gruszczyk, M Hamad, F Allen, EC Hinchy, ... BRITISH JOURNAL OF SURGERY 105, 7-7, 2018 | | 2018 |
| How cellular ATP/ADP ratios and reactive oxygen species affect AMPK signalling E Hinchy | | 2017 |
| Mitochondrial Hydrogen Peroxide as a Redox Signal EC Hinchy, MP Murphy, MCM Vissers, MB Hampton, AJ Kettle Hydrogen Peroxide Metabolism in Health and Disease, 149-160, 2017 | | 2017 |
