Human TLR3 recognizes dengue virus and modulates viral replication in vitro YT Tsai, SY Chang, CN Lee, CL Kao Cellular microbiology 11 (4), 604-615, 2009 | 253 | 2009 |
Long-term safety and efficacy of human-induced pluripotent stem cell (iPS) grafts in a preclinical model of retinitis pigmentosa YT Tsai, Y Li, CW Hsu, D Erol, J Yang, WH Wu, RJ Davis, D Egli, ... Molecular Medicine 18 (1), 1312, 2012 | 210 | 2012 |
CRISPR repair reveals causative mutation in a preclinical model of retinitis pigmentosa WH Wu, YT Tsai, S Justus, TT Lee, L Zhang, CS Lin, AG Bassuk, ... Molecular Therapy 24 (8), 1388-1394, 2016 | 126 | 2016 |
Clustered Regularly Interspaced Short Palindromic Repeats-Based Genome Surgery for the Treatment of Autosomal Dominant Retinitis Pigmentosa TSH Tsai YT, Wu WH, Lee TT, Wu WP, Xu CL, Park KS, Cui X, Justus S, Lin CS ... Ophthalmology 125 (9), 1421-1430., 2018 | 122 | 2018 |
Validation of genome-wide association study (GWAS)-identified disease risk alleles with patient-specific stem cell lines J Yang, Y Li, L Chan, YT Tsai, WH Wu, HV Nguyen, CW Hsu, X Li, ... Human molecular genetics 23 (13), 3445-3455, 2014 | 107 | 2014 |
Gene therapy in patient-specific stem cell lines and a preclinical model of retinitis pigmentosa with membrane frizzled-related protein defects Y Li, WH Wu, CW Hsu, HV Nguyen, YT Tsai, L Chan, T Nagasaki, ... Molecular Therapy 22 (9), 1688-1697, 2014 | 97 | 2014 |
Reprogramming metabolism by targeting sirtuin 6 attenuates retinal degeneration L Zhang, J Du, S Justus, CW Hsu, L Bonet-Ponce, WH Wu, YT Tsai, ... The Journal of clinical investigation 126 (12), 4659-4673, 2016 | 93 | 2016 |
Halting progressive neurodegeneration in advanced retinitis pigmentosa SF Koch, YT Tsai, JK Duong, WH Wu, CW Hsu, WP Wu, L Bonet-Ponce, ... The Journal of clinical investigation 125 (9), 3704-3713, 2015 | 81 | 2015 |
Gene and cell‐based therapies for inherited retinal disorders: An update JD Sengillo, S Justus, YT Tsai, T Cabral, SH Tsang American Journal of Medical Genetics Part C: Seminars in Medical Genetics …, 2016 | 79 | 2016 |
Gene Therapy Restores Mfrp and Corrects Axial Eye Length G Velez, SH Tsang, YT Tsai, CW Hsu, A Gore, AH Abdelhakim, ... Scientific Reports 7 (1), 16151, 2017 | 41 | 2017 |
Therapeutic Margins in a Novel Preclinical Model of Retinitis Pigmentosa RJ Davis, YT Tsai, CW Hsu, KJ Wert, J Sancho-Pelluz, CS Lin, SH Tsang The Journal of Neuroscience 33 (33), 13475-13483, 2013 | 40 | 2013 |
Emerging Treatments for Retinitis Pigmentosa MK LIN, YIT TSAI, SH TSANG Retinal physician 12, 52, 2015 | 27 | 2015 |
Genetic rescue models refute nonautonomous rod cell death in retinitis pigmentosa SF Koch, JK Duong, CW Hsu, YT Tsai, CS Lin, CA Wahl-Schott, SH Tsang Proceedings of the National Academy of Sciences 114 (20), 5259-5264, 2017 | 26 | 2017 |
Vigabatrin-induced retinal toxicity is partially mediated by signaling in rod and cone photoreceptors J Yang, MC Naumann, YT Tsai, J Tosi, D Erol, CS Lin, RJ Davis, ... Public Library of Science 7 (8), e43889, 2012 | 25 | 2012 |
Prime editing for inherited retinal diseases BL Costa, SR Levi, E Eulau, YT Tsai, PMJ Quinn Frontiers in Genome Editing 3, 775330, 2021 | 24 | 2021 |
CRISPR genome surgery in a novel humanized model for autosomal dominant retinitis pigmentosa WH Wu, YT Tsai, IW Huang, CH Cheng, CW Hsu, X Cui, J Ryu, ... Molecular Therapy 30 (4), 1407-1420, 2022 | 22 | 2022 |
Genetic rescue reverses microglial activation in preclinical models of retinitis pigmentosa L Zhang, X Cui, R Jauregui, KS Park, S Justus, YT Tsai, JK Duong, ... Molecular Therapy 26 (8), 1953-1964, 2018 | 21 | 2018 |
Silencing of tuberin enhances photoreceptor survival and function in a preclinical model of retinitis pigmentosa (an american ophthalmological society thesis) SH Tsang, L Chan, YT Tsai, WH Wu, CW Hsu, J Yang, J Tosi, KJ Wert, ... Transactions of the American Ophthalmological Society 112, 103, 2014 | 18 | 2014 |
Rod metabolic demand drives progression in retinopathies MK Lin, SH Kim, L Zhang, YT Tsai, SH Tsang Taiwan Journal of Ophthalmology 5 (3), 105-108, 2015 | 17 | 2015 |
CRISPR base editing in induced pluripotent stem cells YJ Chang, CL Xu, X Cui, AG Bassuk, VB Mahajan, YT Tsai, SH Tsang Stem Cells and Aging: Methods and Protocols, 337-346, 2019 | 15 | 2019 |