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Divya S Vinjamur
Divya S Vinjamur
Boston Children's Hospital, Harvard Medical School
在 childrens.harvard.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis
MC Canver, EC Smith, F Sher, L Pinello, NE Sanjana, O Shalem, ...
Nature 527 (7577), 192-197, 2015
9762015
Recent progress in understanding and manipulating haemoglobin switching for the haemoglobinopathies
DS Vinjamur, DE Bauer, SH Orkin
British journal of haematology 180 (5), 630-643, 2018
1212018
Synthetic lethality of Wnt pathway activation and asparaginase in drug-resistant acute leukemias
L Hinze, M Pfirrmann, S Karim, J Degar, C McGuckin, D Vinjamur, ...
Cancer cell 35 (4), 664-676. e7, 2019
1042019
Rational targeting of a NuRD subcomplex guided by comprehensive in situ mutagenesis
F Sher, M Hossain, D Seruggia, VAC Schoonenberg, Q Yao, P Cifani, ...
Nature genetics 51 (7), 1149-1159, 2019
1002019
Transcription factors KLF1 and KLF2 positively regulate embryonic and fetal β-globin genes through direct promoter binding
YN Alhashem, DS Vinjamur, M Basu, U Klingmüller, KML Gaensler, ...
Journal of Biological Chemistry 286 (28), 24819-24827, 2011
612011
ZNF410 represses fetal globin by singular control of CHD4
DS Vinjamur, Q Yao, MA Cole, C McGuckin, C Ren, J Zeng, M Hossain, ...
Nature genetics 53 (5), 719-728, 2021
542021
Growing and genetically manipulating human umbilical cord blood-derived erythroid progenitor (HUDEP) cell lines
DS Vinjamur, DE Bauer
Erythropoiesis: Methods and Protocols, 275-284, 2018
502018
Common variants in signaling transcription-factor-binding sites drive phenotypic variability in red blood cell traits
A Choudhuri, E Trompouki, BJ Abraham, LM Colli, KH Kock, W Mallard, ...
Nature genetics 52 (12), 1333-1345, 2020
312020
Krüppel-like transcription factors KLF1 and KLF2 have unique and coordinate roles in regulating embryonic erythroid precursor maturation
DS Vinjamur, KJ Wade, SF Mohamad, JL Haar, ST Sawyer, JA Lloyd
Haematologica 99 (10), 1565, 2014
272014
Development of a double shmiR lentivirus effectively targeting both BCL11A and ZNF410 for enhanced induction of fetal hemoglobin to treat β-hemoglobinopathies
B Liu, C Brendel, DS Vinjamur, Y Zhou, C Harris, M McGuinness, ...
Molecular Therapy 30 (8), 2693-2708, 2022
242022
Krüppel-like transcription factor KLF1 is required for optimal γ-and β-globin expression in human fetal erythroblasts
DS Vinjamur, YN Alhashem, SF Mohamad, P Amin, DC Williams Jr, ...
PLoS One 11 (2), e0146802, 2016
202016
Molecular analysis of the erythroid phenotype of a patient with BCL11A haploinsufficiency
MW Wessels, MH Cnossen, TB van Dijk, N Gillemans, KLJ Schmidt, ...
Blood advances 5 (9), 2339-2349, 2021
132021
Crispr-Cas9 saturating mutagenesis reveals an Achilles heel in the BCL11A erythroid enhancer for fetal hemoglobin induction (by genome editing)
DE Bauer, MC Canver, EC Smith, F Sher, L Pinello, NE Sanjana, ...
Blood 126 (23), 638, 2015
72015
Synthetic lethality of wnt pathway activation and asparaginase in drug-resistant acute leukemias
L Hinze, M Pfirrmann, S Karim, J Degar, C McGuckin, D Vinjamur, ...
Blood, The Journal of the American Society of Hematology 132 (Supplement 1 …, 2018
12018
IGF2BP1 Orchestrates Post-Transcriptional Control of Globin Switching through Direct Binding to Globins and Their Regulators
S Coyne, T Wu, D Vinjamur, M Hossain, DE Bauer
Blood 144 (Supplement 1), 414-414, 2024
2024
Targeting znf410 for fetal hemoglobin induction in betahemoglobinopathies
DE Bauer, D Vinjamur
US Patent App. 18/016,190, 2023
2023
Development of a double shmiR lentivirus effectively targeting both BCL11A and ZNF410 for enhanced induction of fetal hemoglobin to treat beta-hemoglobinopathies
B Liu, C Brendel, DS Vinjamur, C Harris, M McGuinness, H Xu, DE Bauer, ...
HUMAN GENE THERAPY 32 (19-20), A58-A58, 2021
2021
ZNF410 represses fetal globin by devoted control of CHD4/NuRD [preprint]
DS Vinjamur, Q Yao, MA Cole, C McGuckin, C Ren, J Zeng, M Hossain, ...
2020
S859 GENOME‐WIDE CRISPR‐CAS9 SCREEN REVEALS SYNTHETIC LETHALITY OF WNT PATHWAY ACTIVATION AND ASPARAGINASE IN DRUG‐RESISTANT ACUTE LEUKEMIAS
L Hinze, M Pfirrmann, S Karim, J Degar, C McGuckin, D Vinjamur, ...
HemaSphere 3, 384, 2019
2019
Comprehensive Integrated Genomic Perturbations Reveal Molecular Mechanisms of Red Blood Cell Trait Associations
Y Wu, MA Cole, A Mousas, J Zeng, Q Yao, D Vinjamur, R Kurita, ...
Blood 132, 532, 2018
2018
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