ECM1 is an essential factor for the determination of M1 macrophage polarization in IBD in response to LPS stimulation Y Zhang, X Li, Z Luo, L Ma, S Zhu, Z Wang, J Wen, S Cheng, W Gu, ... Proceedings of the National Academy of Sciences 117 (6), 3083-3092, 2020 | 94 | 2020 |
ECM1 prevents activation of transforming growth factor β, hepatic stellate cells, and fibrogenesis in mice W Fan, T Liu, W Chen, S Hammad, T Longerich, I Hausser, Y Fu, N Li, ... Gastroenterology 157 (5), 1352-1367. e13, 2019 | 82 | 2019 |
Allergen protease-activated stress granule assembly and gasdermin D fragmentation control interleukin-33 secretion W Chen, S Chen, C Yan, Y Zhang, R Zhang, M Chen, S Zhong, W Fan, ... Nature immunology 23 (7), 1021-1030, 2022 | 62 | 2022 |
Extracellular matrix protein 1 promotes follicular helper T cell differentiation and antibody production L He, W Gu, M Wang, X Chang, X Sun, Y Zhang, X Lin, C Yan, W Fan, ... Proceedings of the National Academy of Sciences 115 (34), 8621-8626, 2018 | 48 | 2018 |
Transforming growth factor β latency: A mechanism of cytokine storage and signalling regulation in liver homeostasis and disease Y Li, W Fan, F Link, S Wang, S Dooley JHEP Reports 4 (2), 100397, 2022 | 44 | 2022 |
AGER1 downregulation associates with fibrosis in nonalcoholic steatohepatitis and type 2 diabetes A Dehnad, W Fan, JX Jiang, SR Fish, Y Li, S Das, G Mozes, KA Wong, ... The Journal of Clinical Investigation 130 (8), 4320-4330, 2020 | 37 | 2020 |
Non-alcoholic fatty liver disease and liver fibrosis during aging Y Li, NT Adeniji, W Fan, K Kunimoto, NJ Török Aging and disease 13 (4), 1239, 2022 | 27 | 2022 |
IFN-λ4 desensitizes the response to IFN-α treatment in chronic hepatitis C through long-term induction of USP18 W Fan, S Xie, X Zhao, N Li, C Chang, L Li, G Yu, X Chi, Y Pan, J Niu, ... Journal of General Virology 97 (9), 2210-2220, 2016 | 27 | 2016 |
Matrix viscoelasticity promotes liver cancer progression in the pre-cirrhotic liver W Fan, K Adebowale, L Váncza, Y Li, MF Rabbi, K Kunimoto, D Chen, ... Nature 626 (7999), 635-642, 2024 | 25 | 2024 |
TRIM34 attenuates colon inflammation and tumorigenesis by sustaining barrier integrity Q Lian, S Yan, Q Yin, C Yan, W Zheng, W Gu, X Zhao, W Fan, X Li, L Ma, ... Cellular & molecular immunology 18 (2), 350-362, 2021 | 19 | 2021 |
Nonphagocytic activation of NOX2 is implicated in progressive nonalcoholic steatohepatitis during aging JX Jiang, SR Fish, A Tomilov, Y Li, W Fan, A Dehnad, D Gae, S Das, ... Hepatology 72 (4), 1204-1218, 2020 | 15 | 2020 |
Junctional and somatic hypermutation-induced CX4C motif is critical for the recognition of a highly conserved epitope on HCV E2 by a human broadly neutralizing … C Yi, J Xia, L He, Z Ling, X Wang, Y Yan, J Wang, X Zhao, W Fan, X Sun, ... Cellular & molecular immunology 18 (3), 675-685, 2021 | 11 | 2021 |
HTR2A agonists play a therapeutic role by restricting ILC2 activation in papain-induced lung inflammation Z Wang, C Yan, Q Du, Y Huang, X Li, D Zeng, R Mao, RK Gurram, ... Cellular & Molecular Immunology 20 (4), 404-418, 2023 | 4 | 2023 |
Salvianolic acid B attenuates liver fibrosis by targeting Ecm1 and inhibiting hepatocyte ferroptosis Y Fu, X Zhou, L Wang, W Fan, S Gao, D Zhang, Z Ling, Y Zhang, L Ma, ... Redox Biology 69, 103029, 2024 | 3 | 2024 |
Shc is implicated in calreticulin-mediated sterile inflammation in alcoholic hepatitis Y Li, JX Jiang, W Fan, SR Fish, S Das, P Gupta, G Mozes, L Vancza, ... Cellular and molecular gastroenterology and hepatology 15 (1), 197-211, 2023 | 3 | 2023 |
3D Imaging of the Liver Extracellular Matrix in a Mouse Model of Non-Alcoholic Steatohepatitis W Fan, Y Li, K Kunimoto, NJ Török JoVE (Journal of Visualized Experiments), e63106, 2022 | 1 | 2022 |
Noninvasive Fibrosis Biomarkers in Patients With NASH With Diabetes W Fan, NJ Torok Hepatology Communications 5 (4), 553-555, 2021 | 1 | 2021 |
FRI-539 EGF/STAT1 signals to maintain ECM1 expression in hepatic homeostasis are disrupted by IFNγ/NRF2 in chronic liver disease Y Li, F Link, W Fan, R Feng, S Hammad, H Weng, M Ebert, S Dooley, ... Journal of Hepatology 80, S287-S288, 2024 | | 2024 |
THU-526 The hepatoprotective role of ECM1: inhibition of mediators of latent TGF-β1 activation and implications for anti-fibrotic treatment strategies in chronic liver disease F Link, Y Li, J Zhao, S Munker, W Fan, Z Nwosu, Y Yao, S Hammad, ... Journal of Hepatology 80, S263, 2024 | | 2024 |
Metabolic dysfunction− associated liver disease and diabetes: Matrix remodeling, fibrosis, and therapeutic implications W Fan, TM Bradford, NJ Török Annals of the New York Academy of Sciences, 2024 | | 2024 |