A bright future for precision medicine: advances in fluorescent chemical probe design and their clinical application M Garland, JJ Yim, M Bogyo Cell chemical biology 23 (1), 122-136, 2016 | 258 | 2016 |
Chemical strategies to target bacterial virulence M Garland, S Loscher, M Bogyo Chemical reviews 117 (5), 4422-4461, 2017 | 142 | 2017 |
A small-molecule antivirulence agent for treating Clostridium difficile infection KO Bender, M Garland, JA Ferreyra, AJ Hryckowian, MA Child, AW Puri, ... Science translational medicine 7 (306), 306ra148-306ra148, 2015 | 136 | 2015 |
Identification of a S. aureus virulence factor by activity-based protein profiling (ABPP) CS Lentz, JR Sheldon, LA Crawford, R Cooper, M Garland, MR Amieva, ... Nature chemical biology 14 (6), 609-617, 2018 | 86 | 2018 |
Small-molecule inhibition of a depalmitoylase enhances Toxoplasma host-cell invasion MA Child, CI Hall, JR Beck, LO Ofori, VE Albrow, M Garland, PW Bowyer, ... Nature chemical biology 9 (10), 651-656, 2013 | 69 | 2013 |
Labeling of active proteases in fresh-frozen tissues by topical application of quenched activity-based probes NP Withana, M Garland, M Verdoes, LO Ofori, E Segal, M Bogyo Nature protocols 11 (1), 184-191, 2016 | 58 | 2016 |
A protease-activated, near-infrared fluorescent probe for early endoscopic detection of premalignant gastrointestinal lesions JJ Yim, S Harmsen, K Flisikowski, T Flisikowska, H Namkoong, M Garland, ... Proceedings of the National Academy of Sciences 118 (1), e2008072118, 2021 | 49 | 2021 |
Dual-modality activity-based probes as molecular imaging agents for vascular inflammation NP Withana, T Saito, X Ma, M Garland, C Liu, H Kosuge, M Amsallem, ... Journal of Nuclear Medicine 57 (10), 1583-1590, 2016 | 49 | 2016 |
Structure of the Trehalose-6-phosphate Phosphatase from Brugia malayi Reveals Key Design Principles for Anthelmintic Drugs JD Farelli, BD Galvin, Z Li, C Liu, M Aono, M Garland, OE Hallett, ... PLoS pathogens 10 (7), e1004245, 2014 | 44 | 2014 |
The clinical drug ebselen attenuates inflammation and promotes microbiome recovery in mice after antibiotic treatment for CDI M Garland, AJ Hryckowian, M Tholen, KO Bender, WW Van Treuren, ... Cell Reports Medicine 1 (1), 2020 | 38 | 2020 |
Homo sapiens Dullard Protein Phosphatase Shows a Preference for the Insulin-Dependent Phosphorylation Site of Lipin1 R Wu, M Garland, D Dunaway-Mariano, KN Allen Biochemistry 50 (15), 3045-3047, 2011 | 31 | 2011 |
Synthetic fluorogenic peptides reveal dynamic substrate specificity of depalmitoylases N Amara, IT Foe, O Onguka, M Garland, M Bogyo Cell chemical biology 26 (1), 35-47. e7, 2019 | 28 | 2019 |
Pre-trained deep convolutional neural network for clostridioides difficile bacteria cytotoxicity classification based on fluorescence images A Brodzicki, J Jaworek-Korjakowska, P Kleczek, M Garland, M Bogyo Sensors 20 (23), 6713, 2020 | 27 | 2020 |
The glucosyltransferase activity of C. difficile Toxin B is required for disease pathogenesis TW Bilverstone, M Garland, RJ Cave, ML Kelly, M Tholen, DM Bouley, ... PLoS Pathogens 16 (9), e1008852, 2020 | 27 | 2020 |
Development of an activity-based probe for acyl-protein thioesterases M Garland, CJ Schulze, IT Foe, WA van der Linden, MA Child, M Bogyo PloS one 13 (1), e0190255, 2018 | 20 | 2018 |
Covalent modifiers of botulinum neurotoxin counteract toxin persistence M Garland, BM Babin, SI Miyashita, S Loscher, Y Shen, M Dong, M Bogyo ACS chemical biology 14 (1), 76-87, 2018 | 16 | 2018 |
Toxoplasma DJ-1 regulates organelle secretion by a direct interaction with calcium-dependent protein kinase 1 MA Child, M Garland, I Foe, P Madzelan, M Treeck, WA Van Der Linden, ... MBio 8 (1), 10.1128/mbio. 02189-16, 2017 | 14 | 2017 |
An Automatic Analysis System for High-Throughput Clostridium Difficile Toxin Activity Screening M Garland, J Jaworek-Korjakowska, U Libal, M Bogyo, M Sieńczyk Applied Sciences 8 (9), 1512, 2018 | 4 | 2018 |
Targeted plasma metabolomics combined with machine learning for the diagnosis of severe acute respiratory syndrome virus type 2 AT Le, M Wu, A Khan, N Phillips, P Rajpurkar, M Garland, K Magid, ... Frontiers in Microbiology 13, 1059289, 2023 | 2 | 2023 |
Chemical Tools to Interrogate and Inhibit Bacterial Exotoxins MM Garland Stanford University, 2021 | 1 | 2021 |