Gut microbial metabolites limit the frequency of autoimmune T cells and protect against type 1 diabetes E Mariño, JL Richards, KH McLeod, D Stanley, YA Yap, J Knight, ... Nature immunology 18 (5), 552-562, 2017 | 644 | 2017 |
IL-37 requires the receptors IL-18Rα and IL-1R8 (SIGIRR) to carry out its multifaceted anti-inflammatory program upon innate signal transduction CA Nold-Petry, CY Lo, I Rudloff, KD Elgass, S Li, MP Gantier, ... Nature immunology 16 (4), 354-365, 2015 | 432 | 2015 |
Transcriptional signature in microglia associated with Aβ plaque phagocytosis A Grubman, XY Choo, G Chew, JF Ouyang, G Sun, NP Croft, FJ Rossello, ... Nature Communications 12 (1), 1-22, 2021 | 178 | 2021 |
Reprogramming roadmap reveals route to human induced trophoblast stem cells X Liu, JF Ouyang, FJ Rossello, JP Tan, KC Davidson, DS Valdes, ... Nature 586 (7827), 101-107, 2020 | 164 | 2020 |
Comprehensive characterization of distinct states of human naive pluripotency generated by reprogramming X Liu, CM Nefzger, FJ Rossello, J Chen, AS Knaupp, J Firas, E Ford, ... Nature methods 14 (11), 1055-1062, 2017 | 160 | 2017 |
Macrophages provide a transient muscle stem cell niche via NAMPT secretion D Ratnayake, PD Nguyen, FJ Rossello, VC Wimmer, JL Tan, LA Galvis, ... Nature 591 (7849), 281-287, 2021 | 145 | 2021 |
Transient and permanent reconfiguration of chromatin and transcription factor occupancy drive reprogramming AS Knaupp, S Buckberry, J Pflueger, SM Lim, E Ford, MR Larcombe, ... Cell stem cell 21 (6), 834-845. e6, 2017 | 121 | 2017 |
Mesenchymal niche-derived neuregulin-1 drives intestinal stem cell proliferation and regeneration of damaged epithelium T Jardé, WH Chan, FJ Rossello, TK Kahlon, M Theocharous, TK Arackal, ... Cell stem cell 27 (4), 646-662. e7, 2020 | 109 | 2020 |
DDX5 plays essential transcriptional and post-transcriptional roles in the maintenance and function of spermatogonia JMD Legrand, AL Chan, HM La, FJ Rossello, ML Änkö, FV Fuller-Pace, ... Nature communications 10 (1), 2278, 2019 | 93 | 2019 |
Identification of dynamic undifferentiated cell states within the male germline HM La, JA Mäkelä, AL Chan, FJ Rossello, CM Nefzger, JMD Legrand, ... Nature Communications 9 (1), 2819, 2018 | 80 | 2018 |
Muscle stem cells undergo extensive clonal drift during tissue growth via Meox1-mediated induction of G2 cell-cycle arrest PD Nguyen, DB Gurevich, C Sonntag, L Hersey, S Alaei, HT Nim, ... Cell Stem Cell 21 (1), 107-119. e6, 2017 | 70 | 2017 |
BTB-ZF transcriptional regulator PLZF modifies chromatin to restrain inflammatory signaling programs AJ Sadler, FJ Rossello, L Yu, JA Deane, X Yuan, D Wang, AT Irving, ... Proceedings of the National Academy of Sciences 112 (5), 1535-1540, 2015 | 66 | 2015 |
A synthetic lethal interaction between glutathione synthesis and mitochondrial reactive oxygen species provides a tumor-specific vulnerability dependent on STAT3 DJ Garama, TJ Harris, CL White, FJ Rossello, M Abdul-Hay, DJ Gough, ... Molecular and cellular biology 35 (21), 3646-3656, 2015 | 65 | 2015 |
Cell type of origin dictates the route to pluripotency CM Nefzger, FJ Rossello, J Chen, X Liu, AS Knaupp, J Firas, JM Paynter, ... Cell reports 21 (10), 2649-2660, 2017 | 57 | 2017 |
FGFR2 mutation in 46,XY sex reversal with craniosynostosis S Bagheri-Fam, M Ono, L Li, L Zhao, J Ryan, R Lai, Y Katsura, ... Human molecular genetics 24 (23), 6699-6710, 2015 | 57 | 2015 |
Low-dose histone deacetylase inhibitor treatment leads to tumor growth arrest and multi-lineage differentiation of malignant rhabdoid tumors A Muscat, D Popovski, WSN Jayasekara, FJ Rossello, M Ferguson, ... Clinical Cancer Research 22 (14), 3560-3570, 2016 | 47 | 2016 |
Inhibition of activin signaling in lung adenocarcinoma increases the therapeutic index of platinum chemotherapy KD Marini, DR Croucher, RA McCloy, V Vaghjiani, A Gonzalez-Rajal, ... Science translational medicine 10 (451), eaat3504, 2018 | 43 | 2018 |
Genomic characterisation of small cell lung cancer patient-derived xenografts generated from endobronchial ultrasound-guided transbronchial needle aspiration specimens TL Leong, KD Marini, FJ Rossello, SN Jayasekara, PA Russell, ... PloS one 9 (9), e106862, 2014 | 43 | 2014 |
Overcoming monocarboxylate transporter 8 (MCT8)-deficiency to promote human oligodendrocyte differentiation and myelination JY Lee, MJ Kim, D Deliyanti, MF Azari, F Rossello, A Costin, G Ramm, ... EBioMedicine 25, 122-135, 2017 | 42 | 2017 |
Role of epigenetics in the etiology of germ cell cancer YG Van Der Zwan, H Stoop, F Rossello, SJ White, LH Looijenga Int J Dev Biol 57 (2-4), 299-308, 2013 | 40 | 2013 |