| A futile metabolic cycle activated in adipocytes by antidiabetic agents HP Guan, Y Li, MV Jensen, CB Newgard, CM Steppan, MA Lazar Nature medicine 8 (10), 1122-1128, 2002 | 494 | 2002 |
| Corepressors selectively control the transcriptional activity of PPARγ in adipocytes HP Guan, T Ishizuka, PC Chui, M Lehrke, MA Lazar Genes & development 19 (4), 453-461, 2005 | 368 | 2005 |
| Systemic pan-AMPK activator MK-8722 improves glucose homeostasis but induces cardiac hypertrophy RW Myers, HP Guan, J Ehrhart, A Petrov, S Prahalada, E Tozzo, X Yang, ... Science 357 (6350), 507-511, 2017 | 277 | 2017 |
| PPARγ regulates adipose triglyceride lipase in adipocytes in vitro and in vivo EE Kershaw, M Schupp, HP Guan, NP Gardner, MA Lazar, JS Flier American Journal of Physiology-Endocrinology and Metabolism 293 (6), E1736-E1745, 2007 | 253 | 2007 |
| PPARγ regulates adipocyte cholesterol metabolism via oxidized LDL receptor 1 PC Chui, HP Guan, M Lehrke, MA Lazar The Journal of clinical investigation 115 (8), 2244-2256, 2005 | 246 | 2005 |
| Glucagon receptor antagonism induces increased cholesterol absorption [S] HP Guan, X Yang, K Lu, SP Wang, JM Castro-Perez, S Previs, M Wright, ... Journal of lipid research 56 (11), 2183-2195, 2015 | 79 | 2015 |
| Accelerated fatty acid oxidation in muscle averts fasting-induced hepatic steatosis in SJL/J mice HP Guan, JL Goldstein, MS Brown, G Liang Journal of Biological Chemistry 284 (36), 24644-24652, 2009 | 74 | 2009 |
| Diet-dependent cardiovascular lipid metabolism controlled by hepatic LXRα M Lehrke, C Lebherz, SC Millington, HP Guan, J Millar, DJ Rader, ... Cell metabolism 1 (5), 297-308, 2005 | 61 | 2005 |
| Discovery of MK-8722: a systemic, direct pan-activator of AMP-activated protein kinase D Feng, T Biftu, FA Romero, A Kekec, J Dropinski, A Kassick, S Xu, ... ACS medicinal chemistry letters 9 (1), 39-44, 2018 | 47 | 2018 |
| Synphilin in normal human brains and in synucleinopathies: studies with new antibodies IV Murray, MA Medford, HP Guan, SM Rueter, JQ Trojanowski, VMY Lee Acta neuropathologica 105, 177-184, 2003 | 44 | 2003 |
| Pharmacological AMPK activation induces transcriptional responses congruent to exercise in skeletal and cardiac muscle, adipose tissues and liver ES Muise, HP Guan, J Liu, AR Nawrocki, X Yang, C Wang, CG Rodríguez, ... PLoS One 14 (2), e0211568, 2019 | 36 | 2019 |
| Effects of small interfering RNA-mediated hepatic glucagon receptor inhibition on lipid metabolism in db/db mice [S] S Han, TE Akiyama, SF Previs, K Herath, TP Roddy, KK Jensen, HP Guan, ... Journal of lipid research 54 (10), 2615-2622, 2013 | 33 | 2013 |
| Physiological expression of AMPKγ2RG mutation causes Wolff-Parkinson-White syndrome and induces kidney injury in mice X Yang, J Mudgett, MF Champy, H Jacobs, L Monassier, G Pavlovic, ... Journal of Biological Chemistry 291 (45), 23428-23439, 2016 | 26 | 2016 |
| The fatty acid synthase inhibitor platensimycin improves insulin resistance without inducing liver steatosis in mice and monkeys SB Singh, L Kang, AR Nawrocki, D Zhou, M Wu, S Previs, C Miller, H Liu, ... PLoS One 11 (10), e0164133, 2016 | 24 | 2016 |
| Factors affecting insulin-regulated hepatic gene expression HP Guan, G Chen Progress in Molecular Biology and Translational Science 121, 165-215, 2014 | 19 | 2014 |
| Neuroprotective effect of L-lysine monohydrochloride on acute iterative anoxia in rats with quantitative analysis of electrocorticogram G Hong-Ping, KU Bao-Shan Life Sciences 65 (2), PL19-PL25, 1999 | 10 | 1999 |
| Correction: The fatty acid synthase inhibitor platensimycin improves insulin resistance without inducing liver steatosis in mice and monkeys SB Singh, L Kang, AR Nawrocki, D Zhou, M Wu, S Previs, C Miller, H Liu, ... Plos one 12 (1), e0170721, 2017 | 3 | 2017 |
| Methods of treating diabetes by administering a glucagon receptor antagonist in combination with a cholesterol absorption inhibitor HP Guan, JM Castro-Perez, HR Davis, SE Engel, DG Johns, S Lin, ... US Patent App. 14/649,651, 2015 | 1 | 2015 |
| Methods of treating diabetes by administering a glucagon receptor antagonist in combination with a cholesterol absorption inhibitor HP Guan, JM Castro-Perez, HR Davis, SE Engel, DG Johns, S Lin, ... US Patent 11,077,092, 2021 | | 2021 |
| Evolution of long and short acting pan-AMPK activators as exercise mimetics J Apgar, R Wilkening, J Hicks, D Feng, L Wei, K Leavitt, J Dropinski, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 258, 2019 | | 2019 |
