Discovery of microbial natural products by activation of silent biosynthetic gene clusters PJ Rutledge, GL Challis Nature reviews microbiology 13 (8), 509-523, 2015 | 955 | 2015 |
Chemical sensors that incorporate click-derived triazoles YH Lau, PJ Rutledge, M Watkinson, MH Todd Chemical Society Reviews 40 (5), 2848-2866, 2011 | 440 | 2011 |
Metal complexes as a promising source for new antibiotics A Frei, J Zuegg, AG Elliott, M Baker, S Braese, C Brown, F Chen, ... Chemical science 11 (10), 2627-2639, 2020 | 375 | 2020 |
The reaction cycle of isopenicillin N synthase observed by X-ray diffraction NI Burzlaff, PJ Rutledge, IJ Clifton, CMH Hensgens, M Pickford, ... Nature 401 (6754), 721-724, 1999 | 226 | 1999 |
Combined “dual” absorption and fluorescence smartphone spectrometers MA Hossain, J Canning, S Ast, K Cook, PJ Rutledge, A Jamalipour Optics letters 40 (8), 1737-1740, 2015 | 124 | 2015 |
Lab-in-a-phone: smartphone-based portable fluorometer for pH measurements of environmental water A Hossain, J Canning, S Ast, PJ Rutledge, TL Yen, A Jamalipour IEEE Sensors Journal 15 (9), 5095-5102, 2014 | 114 | 2014 |
A Click Fluorophore Sensor that Can Distinguish CuII and HgII via Selective Anion‐Induced Demetallation YH Lau, JR Price, MH Todd, PJ Rutledge Chemistry–A European Journal 17 (10), 2850-2858, 2011 | 84 | 2011 |
Recently Discovered Secondary Metabolites from Streptomyces Species HJ Lacey, PJ Rutledge Molecules 27 (3), 887, 2022 | 66 | 2022 |
Recent advances in macrocyclic fluorescent probes for ion sensing JKH Wong, MH Todd, PJ Rutledge Molecules 22 (2), 200, 2017 | 66 | 2017 |
Inhibition studies of Mycobacterium tuberculosis salicylate synthase (MbtI) A Manos‐Turvey, EMM Bulloch, PJ Rutledge, EN Baker, JS Lott, ... ChemMedChem 5 (7), 1067-1079, 2010 | 65 | 2010 |
Nontoxic Metal–Cyclam Complexes, a New Class of Compounds with Potency against Drug-Resistant Mycobacterium tuberculosis M Yu, G Nagalingam, S Ellis, E Martinez, V Sintchenko, M Spain, ... Journal of Medicinal Chemistry 59 (12), 5917-5921, 2016 | 56 | 2016 |
Structural studies on the reaction of isopenicillin N synthase with the truncated substrate analogues δ-(l-α-aminoadipoyl)-l-cysteinyl-glycine and δ-(l-α-aminoadipoyl)-l … AJ Long, IJ Clifton, PL Roach, JE Baldwin, PJ Rutledge, CJ Schofield Biochemistry 44 (17), 6619-6628, 2005 | 56 | 2005 |
Alternative oxidation by isopenicillin N synthase observed by X-ray diffraction JM Ogle, IJ Clifton, PJ Rutledge, JM Elkins, NI Burzlaff, RM Adlington, ... Chemistry & biology 8 (12), 1231-1237, 2001 | 52 | 2001 |
Copper, nickel, and zinc cyclam–amino acid and cyclam–peptide complexes may be synthesized with “click” chemistry and are noncytotoxic M Yu, JR Price, P Jensen, CJ Lovitt, T Shelper, S Duffy, LC Windus, ... Inorganic Chemistry 50 (24), 12823-12835, 2011 | 50 | 2011 |
Efficient deprotection of F-BODIPY derivatives: removal of BF2 using Brønsted acids M Yu, JKH Wong, C Tang, P Turner, MH Todd, PJ Rutledge Beilstein journal of organic chemistry 11, 37, 2015 | 49 | 2015 |
Antitubercular bis-substituted cyclam derivatives: Structure–activity relationships and in vivo studies M Spain, JKH Wong, G Nagalingam, JM Batten, E Hortle, SH Oehlers, ... Journal of Medicinal Chemistry 61 (8), 3595-3608, 2018 | 45 | 2018 |
Isopenicillin N synthase mediates thiolate oxidation to sulfenate in a depsipeptide substrate analogue: implications for oxygen binding and a link to nitrile hydratase? W Ge, IJ Clifton, JE Stok, RM Adlington, JE Baldwin, PJ Rutledge Journal of the American Chemical Society 130 (31), 10096-10102, 2008 | 42 | 2008 |
Crystallographic studies on the reaction of isopenicillin N synthase with an unsaturated substrate analogue JM Elkins, PJ Rutledge, NI Burzlaff, IJ Clifton, RM Adlington, PL Roach, ... Organic & biomolecular chemistry 1 (9), 1455-1460, 2003 | 40 | 2003 |
Reversing the Triazole Topology in a Cyclam‐Triazole‐Dye Ligand Gives a 10‐Fold Brighter Signal Response to Zn2+ in Aqueous Solution S Ast, PJ Rutledge, MH Todd European Journal of Inorganic Chemistry 2012 (34), 5611-5615, 2012 | 38 | 2012 |
Early warning smartphone diagnostics for water security and analysis using real-time pH mapping MA Hossain, J Canning, S Ast, PJ Rutledge, A Jamalipour Photonic Sensors 5, 289-297, 2015 | 37 | 2015 |