| Identification and functional analysis of endothelial tip cell–enriched genes R del Toro, C Prahst, T Mathivet, G Siegfried, JS Kaminker, B Larrivee, ... Blood, The Journal of the American Society of Hematology 116 (19), 4025-4033, 2010 | 514 | 2010 |
| The secretory proprotein convertases furin, PC5, and PC7 activate VEGF-C to induce tumorigenesis G Siegfried, A Basak, JA Cromlish, S Benjannet, J Marcinkiewicz, ... The Journal of clinical investigation 111 (11), 1723-1732, 2003 | 324 | 2003 |
| Hypoxia-induced apelin expression regulates endothelial cell proliferation and regenerative angiogenesis M Eyries, G Siegfried, M Ciumas, K Montagne, M Agrapart, F Lebrin, ... Circulation research 103 (4), 432-440, 2008 | 318 | 2008 |
| Proprotein convertases in tumor progression and malignancy: novel targets in cancer therapy AM Khatib, G Siegfried, M Chrétien, P Metrakos, NG Seidah The American journal of pathology 160 (6), 1921-1935, 2002 | 264 | 2002 |
| Inhibition of proprotein convertases is associated with loss of growth and tumorigenicity of HT-29 human colon carcinoma cells: importance of insulin-like growth factor-1 (IGF … AM Khatib, G Siegfried, A Prat, J Luis, M Chrétien, P Metrakos, NG Seidah Journal of Biological Chemistry 276 (33), 30686-30693, 2001 | 212 | 2001 |
| Selective inhibition of proprotein convertases represses the metastatic potential of human colorectal tumor cells N Scamuffa, G Siegfried, Y Bontemps, L Ma, A Basak, G Cherel, F Calvo, ... The Journal of clinical investigation 118 (1), 352-363, 2008 | 153 | 2008 |
| The Proteolytic Processing of Pro-Platelet-derived Growth Factor-A at RRKR86 by Members of the Proprotein Convertase Family Is Functionally Correlated to … G Siegfried, AM Khatib, S Benjannet, M Chrétien, NG Seidah Cancer research 63 (7), 1458-1463, 2003 | 115 | 2003 |
| Regulation of the stepwise proteolytic cleavage and secretion of PDGF-B by the proprotein convertases G Siegfried, A Basak, W Prichett-Pejic, N Scamuffa, L Ma, S Benjannet, ... Oncogene 24 (46), 6925-6935, 2005 | 103 | 2005 |
| TRP channels in angiogenesis and other endothelial functions T Smani, LJ Gómez, S Regodon, GE Woodard, G Siegfried, AM Khatib, ... Frontiers in physiology 9, 1731, 2018 | 87 | 2018 |
| Opposing function of the proprotein convertases furin and PACE4 on breast cancer cells' malignant phenotypes: role of tissue inhibitors of metalloproteinase-1 M Lapierre, G Siegfried, N Scamuffa, Y Bontemps, F Calvo, NG Seidah, ... Cancer Research 67 (19), 9030-9034, 2007 | 83 | 2007 |
| Apelin: an antithrombotic factor that inhibits platelet function F Adam, AM Khatib, JJ Lopez, C Vatier, S Turpin, A Muscat, F Soulet, ... Blood, The Journal of the American Society of Hematology 127 (7), 908-920, 2016 | 67 | 2016 |
| The proprotein convertase furin is a pro-oncogenic driver in KRAS and BRAF driven colorectal cancer Z He, L Thorrez, G Siegfried, S Meulemans, S Evrard, S Tejpar, AM Khatib, ... Oncogene 39 (17), 3571-3587, 2020 | 55 | 2020 |
| Inactivation of proprotein convertases in T cells inhibits PD-1 expression and creates a favorable immune microenvironment in colorectal cancer M Tomé, A Pappalardo, F Soulet, JJ López, J Olaizola, Y Leger, ... Cancer Research 79 (19), 5008-5021, 2019 | 52 | 2019 |
| Regulation of prohepcidin processing and activity by the subtilisin-like proprotein convertases Furin, PC5, PACE4 and PC7 N Scamuffa, A Basak, C Lalou, A Wargnier, J Marcinkiewicz, G Siegfried, ... Gut 57 (11), 1573-1582, 2008 | 48 | 2008 |
| Proprotein convertases: Key players in inflammation-related malignancies and metastasis G Siegfried, J Descarpentrie, S Evrard, AM Khatib Cancer letters 473, 50-61, 2020 | 47 | 2020 |
| Integration of zebrafish fin regeneration genes with expression data of human tumors in silico uncovers potential novel melanoma markers M Hagedorn, G Siegfried, KB Hooks, AM Khatib Oncotarget 7 (44), 71567, 2016 | 34 | 2016 |
| Zebrafish ProVEGF-C expression, proteolytic processing and inhibitory effect of unprocessed ProVEGF-C during fin regeneration AM Khatib, R Lahlil, N Scamuffa, MA Akimenko, S Ernest, A Lomri, ... PloS one 5 (7), e11438, 2010 | 33 | 2010 |
| ELA/APELA precursor cleaved by furin displays tumor suppressor function in renal cell carcinoma through mTORC1 activation F Soulet, C Bodineau, KB Hooks, J Descarpentrie, I Alves, M Dubreuil, ... JCI insight 5 (14), 2020 | 29 | 2020 |
| MECHANISM OF INHIBITION OF ENDOTHELIN-1–STIMULATED PROTEOGLYCAN AND COLLAGEN SYNTHESIS IN RAT ARTICULAR CHONDROCYTES AM Khatib, G Siegfried, H Messai, F Moldovan, DR Mitrovic Cytokine 17 (5), 254-261, 2002 | 24 | 2002 |
| Regulation of the proprotein convertases expression and activity during regenerative angiogenesis: Role of hypoxia-inducible factor (HIF) J Ma, S Evrard, I Badiola, G Siegfried, AM Khatib European Journal of Cell Biology 96 (5), 457-468, 2017 | 22 | 2017 |
